Search Results - "Khattab, Reham R."
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Advances on Therapeutic Strategies for Alzheimer's Disease: From Medicinal Plant to Nanotechnology
Published in Molecules (Basel, Switzerland) (28-07-2022)“…Alzheimer's disease (AD) is a chronic dysfunction of neurons in the brain leading to dementia. It is characterized by gradual mental failure, abnormal…”
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Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazole-thienopyrimidine hybrid glycosides targeting EGFR
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2021)“…In the current study, new thienopyrimidine conjugates bearing 1,2,3-triazole core and different sugar moieties have been designed and synthesized by…”
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Synthesis and Molecular Docking Study of Novel Pyrimidine Derivatives against COVID-19
Published in Molecules (Basel, Switzerland) (11-01-2023)“…A novel series of pyrido[2,3- ]pyrimidines; pyrido[3,2- ][1,3,4]triazolo; and tetrazolo[1,5- ]pyrimidines were synthesized via different chemical…”
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Synthesis, anticancer activity and molecular docking of new triazolo[4,5-d]pyrimidines based thienopyrimidine system and their derived N-glycosides and thioglycosides
Published in Nucleosides, nucleotides & nucleic acids (02-11-2021)“…A series of new substituted triazolo[4,5-d]pyrimidine derivatives linked to thienopyrimidine ring system were prepared as a hybrid heterocyclic systems, as…”
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A Convenient One‐Pot Synthesis of Thieno[2′,3′:4,5]Pyrimido[1,2‐b]‐[1,2,4,5]Tetrazines
Published in Journal of heterocyclic chemistry (01-04-2018)“…A novel series of thieno[2′,3′:4,5]pyrimido[1,2‐b][1,2,4,5]tetrazin‐6‐one derivatives 14 were prepared from the reaction of…”
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Towards breast cancer targeting: Synthesis of tetrahydroindolocarbazoles, antibreast cancer evaluation, uPA inhibition, molecular genetic and molecular modelling studies
Published in Bioorganic chemistry (01-12-2019)“…[Display omitted] •New series of tetrahydroindolocarbazole derivatives has been synthesized.•Compound 11 expressed GI% values of 99.9% against MCF7 breast…”
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Synthesis, In-Vitro, In-Vivo screening, and molecular docking of disubstituted aminothiazole derivatives and their selenium nanoparticles as potential antiparkinson agents
Published in Journal of molecular structure (05-11-2024)“…•Synthesis of (E)−2-(2-aminothiazol-4-yl)-N'-(substituted benzylidene)acetohydrazide (3a-e).•Synthesis of heterocyclic selenium nanoparticles (3a-e)-SeNPs in…”
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Synthesis, spectrophotometric, voltammetric, and density functional theory studies of tetrahydro[3,2‐b]indolocarbazoles for sensing small molecules
Published in Journal of heterocyclic chemistry (01-01-2021)“…Absorption spectra of tetrahydro[3,2‐b]indolocarbazoles (THICZs) with respective molecular property and alkyl substituents have been prerecorded in diverse…”
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Synthesis, spectrophotometric, voltammetric, and density functional theory studies of tetrahydroindolocarbazoles for sensing small molecules
Published in Journal of heterocyclic chemistry (01-01-2021)“…Absorption spectra of tetrahydro[3,2‐b]indolocarbazoles (THICZs) with respective molecular property and alkyl substituents have been prerecorded in diverse…”
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Novel Pyruvate Kinase (PK) Inhibitors: New Target to Overcome Bacterial Resistance
Published in ChemistrySelect (Weinheim) (20-03-2020)“…In the present investigation, some novel nitro Mannich bases derived from Michael type addition of activated nitro olefin, β‐nitrostyrene with various amines…”
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