Search Results - "Khatib, Jude"

Role of Translesion DNA Synthesis in the Metabolism of Replication-associated Nascent Strand Gaps by Khatib, Jude B, Nicolae, Claudia M, Moldovan, George-Lucian

“…Translesion DNA synthesis (TLS) is a DNA damage tolerance pathway utilized by cells to overcome lesions encountered throughout DNA replication. During…”
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PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis by Khatib, Jude B., Dhoonmoon, Ashna, Moldovan, George-Lucian, Nicolae, Claudia M.

“…Replication stress compromises genomic integrity. Fork blocking lesions such as those induced by cisplatin and other chemotherapeutic agents arrest replication…”
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CAF-1 promotes efficient PrimPol recruitment to nascent DNA for single-stranded DNA gap formation by Straka, Joshua, Khatib, Jude B, Pale, Lindsey, Nicolae, Claudia M, Moldovan, George-Lucian

“…Suppression of single-stranded DNA (ssDNA) gap accumulation at replication forks has emerged as a potential determinant of chemosensitivity in homologous…”
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CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplatin-induced single-stranded DNA gaps by Pale, Lindsey M, Khatib, Jude B, Nusawardhana, Alexandra, Straka, Joshua, Nicolae, Claudia M, Moldovan, George-Lucian

“…Treatment with genotoxic agents, such as platinum compounds, is still the mainstay therapeutical approach for the majority of cancers. Our understanding of the…”
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Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival by Khatib, Jude B., Schleicher, Emily M., Jackson, Lindsey M., Dhoonmoon, Ashna, Moldovan, George-Lucian, Nicolae, Claudia M.

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The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells by Schleicher, Emily M., Dhoonmoon, Ashna, Jackson, Lindsey M., Khatib, Jude B., Nicolae, Claudia M., Moldovan, George-Lucian

“…Maintenance of replication fork stability is essential for genome preservation. Stalled replication forks can be reversed by translocases such as SMARCAL1, and…”
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Mystery burns and nocturnal seizure safety by Wu, Benita Y, Khatib, Jude Z, Krishnamurthy, Smita, Travers, Jeffrey B

“…Thermal burn injuries are common and are associated with physical and psychologic repercussions. For epileptic patients, the risk for environmental injuries is…”
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Plasmacytoid urothelial carcinoma: a multidisciplinary approach to the diagnosis and management by Zorovich, Marcus, Khatib, Jude, Mubeen, Aysha, Gardner, Katie, Patel, Nayana

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Optimal Use of FOLFOXIRI Plus Bevacizumab as First-Line Systemic Treatment in Metastatic Colorectal Cancer by Khatib, Jude, Kainthla, Radhika

“…Purpose of Review Colorectal cancer is the second leading cause of cancer-related deaths in the USA with more than half of diagnosed patients developing…”
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Review of treatments for pseudofolliculitis barbae by Dalia, Yoseph, Khatib, Jude, Odens, Herman, Patel, Tejesh

“…Pseudofolliculitis barbae (PFB) is a chronic inflammatory condition characterized by follicular and perifollicular papules and pustules primarily affecting the…”
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Sarcoidosis Presenting as Intramedullary Spinal Cord Lesions (P2.362) by Thatikunta, Prateek, Khatib, Jude, Baar, Joseph

“…Abstract only…”
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Dietary quality in early-onset gastrointestinal malignancies: NHANES 2005-2018 by Lim, Mir, Goksu, Suleyman Yasin, Khatib, Jude, Reddy, Sarah, Beg, Shaalan Shaalan, Kazmi, Syed Mohammad Ali

“…3549 Background: The incidence of early-onset colorectal, stomach, esophageal, and pancreatic cancer, which occur in individuals <50 years of age, is rising…”
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A Sweet Case of Crohnʼs: 1733 by Chan, Megan Q., Khatib, Jude, Katz, Jeffry

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Impact of HIV Status on Treatment Choice and Outcomes of Primary Central Nervous System Lymphoma in a Minority Enriched Population: Experience from a Safety Net Hospital by Khatib, Jude, Li, Hsiao Ching, Kainthla, Radhika, Ahn, Chul, Sadeghi, Navid

“…Background Primary central nervous system lymphoma (PCNSL) is a rare and aggressive form of non-Hodgkin lymphoma. High-dose methotrexate is the cornerstone of…”
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Wounds resulting from non-malignant haematological disease: a case series by Simman, Richard, Oostra, Drew, Sullivan, Patrick, Wilson, Michael, Khatib, Jude, Jackson, Sarah E

“…A proactive and systemic approach is imperative to preventing wounds due to disorders of non-malignant haematologic disease. Here, the authors provide several…”
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Diffuse Large B-Cell Lymphoma Presenting With Gastric Variceal Bleeding: 1943 by Alsamman, Yasser, Khatib, Jude, Patel, Sheena, Cooper, Gregory

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Association between metastatic pancreatic cancer and environmental quality index by Ozer, Muhammet, Goksu, Suleyman Yasin, Khatib, Jude, Al Mutar, Salwan, Aguilera, Todd Anthony, Zeh, Herbert, Beg, Shaalan Shaalan, Kazmi, Syed Mohammad Ali

“…e16232 Background: Pancreatic cancer ranks as the 3 rd leading cause of cancer mortality. Overall more than 50% of patients have metastatic disease at…”
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Association between Environmental Quality Index and metastatic pancreatic cancer by Ozer, Muhammet, Goksu, Suleyman Yasin, Khatib, Jude, Al Mutar, Salwan, Aguilera, Todd Anthony, Zeh, Herbert, Beg, Muhammad Shaalan, Kazmi, Syed Mohammad Ali

“…Abstract only 521 Background: Pancreatic cancer ranks as the 3 rd leading cause of cancer mortality. Overall more than 50% of patients have metastatic disease…”
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Metastasectomy in colorectal cancer patients with concurrent lung and liver metastasis: Trends in utilization and impact on survival by Khatib, Jude, Goksu, Suleyman Yasin, Reddy, Sarah, Chowattukunnel, Nivan, Sanford, Nina Niu, Sanjeevaiah, Aravind, Beg, Muhammad Shaalan, Kazmi, Syed Mohammad Ali

“…Abstract only 53 Background: Colorectal cancer (CRC) frequently presents with concurrent metastasis to the lung and liver. Metastasectomy may offer extended…”
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Post-Transplant Cyclophosphamide Associated with Increased Early Mixed Donor Chimerism in Myeloid Malignancies; A Single-Center Experience by Hoff, Fieke W., Patel, Prapti A., Chung, Stephen S., Premnath, Naveen, Khatib, Jude, Tadic-Ovcina, Mirjana, AhmedRabie, Abeer, Helton, Debra, Shahan, Jaime, Dryden, Courtney, Patel, Hetalkumari, Aimaz, Afrough, Ramakrishnan Geethakumari, Praveen, Collins, Robert H., Vusirikala, Madhuri, Madanat, Yazan F.

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