Lipoprotein (a) and lipid profile in neonates from mothers with three different types of diabetes mellitus

Lipoprotein (a) and lipid profile in neonates from mothers with three different types of diabetes mellitus

The metabolic components in neonates may be affected by maternal diabetes mellitus. To investigate the alterations in lipid metabolism and the possible atherogenic risk, the lipoprotein a (Lp a), apoproteins, lipid profile, glucose concentrations were measured (ELISA, immunodiffusion and enzymatic)...

Full description

Saved in:
Bibliographic Details
Published in:Clinical biochemistry Vol. 36; no. 7; pp. 563 - 569
Main Authors: AbouGhalia, Azza H, Khater, Lamia M, Abd El-Wahed, Mohamed A, El-Badrawy, Mohamed F
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-10-2003
Subjects:
Apoproteins
Cord blood
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 2 - complications
Female
Gender
Humans
Infant, Newborn - blood
Infant, Newborn, Diseases - blood
Lipid profile
Lipids - blood
Lipoprotein(a) - blood
Lp (a)
Male
Maternal DM
Mothers
Neonates
Pregnancy
Pregnancy in Diabetics - complications
Sex Characteristics
Neonates
Cord blood
Apoproteins
Maternal DM
Lipid profile
Gender
Lp (a)
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The metabolic components in neonates may be affected by maternal diabetes mellitus. To investigate the alterations in lipid metabolism and the possible atherogenic risk, the lipoprotein a (Lp a), apoproteins, lipid profile, glucose concentrations were measured (ELISA, immunodiffusion and enzymatic) in 77 cord blood samples from diabetic and healthy pregnant mothers. The body weight, cord glucose and both apoproteins were increased in neonates of gestational and noninsulin dependent diabetic (GDM, NIDDM) than in neonates of nondiabetic mothers (NNDM). The Lp (a) was not correlated with the blood glucose and didn’t significantly increase in the three neonates groups of diabetic mothers. The apo B/apo A1 and the LDL/HDL ratios were insignificantly increased in relation to the body weight. In neonates of diabetic mothers (NDM), only the blood glucose and Lp (a) differ between both sexes. NDM may have disturbed lipid metabolism, which require special care to them and to their mothers during the prenatal period.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-9120
1873-2933
DOI:10.1016/S0009-9120(03)00077-8