Search Results - "Khaspekova, S. G"
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Activity of tissue factor in microparticles produced in vitro by endothelial cells, monocytes, granulocytes, and platelets
Published in Biochemistry (Moscow) (01-02-2016)“…Activity of tissue factor (TF) in membrane microparticles (MPs) produced in vitro by endothelial cells (ECs), monocytes, THP-1 monocytic cells, granulocytes,…”
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2
Diagnostics of thrombocytopenias
Published in Terapevtic̆eskii arhiv (17-08-2018)“…Laboratory methods used for the diagnostics of thrombocytopenias are reviewed. Differential diagnosis is usually carried out between immune and hypoproductive…”
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3
Maternal incompatibilities with fetal human platelet alloantigens -1a, -1b and -15 are the main causes of neonatal alloimmune thrombocytopenia in Russia
Published in Terapevtic̆eskii arhiv (17-08-2018)“…Mechanisms underlying the development of neonatal alloimmune thrombocytopenia (NAIT) in in Russia have been studied. Genetic polymorphisms of human platelet…”
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4
Characteristics of a New DNA Aptamer, Direct Inhibitor of Thrombin
Published in Bulletin of experimental biology and medicine (01-02-2011)“…Characteristics of a new antithrombin DNA-aptamer RE31 were studied. This aptamer inhibited thrombin formation in human plasma catalyzed by exogenous…”
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Factors influencing platelet aggregation in patients with acute coronary syndrome
Published in Terapevtic̆eskii arhiv (01-01-2014)“…To study factors influencing platelet aggregation in patients with acute coronary syndrome (ACS). The investigation enrolled 147 patients with ACS. Their blood…”
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6
Inhibition of Thrombin Activity with DNA-Aptamers
Published in Bulletin of experimental biology and medicine (01-07-2009)“…The effects of two DNA aptamers (oligonucleotides) 15TBA and 31TBA (15- and 31-mer thrombin-binding aptamers, respectively) on thrombin activity were studied…”
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7
Reticulated platelets – a new risk factor of atherothrombosis?
Published in Aterotromboz (Online) (13-07-2021)“…In this review we described the properties of reticulated platelets (RP) and showed how variations of their content might influence platelet activity, efficacy…”
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Glycoprotein IIb-IIIa content and platelet aggregation in healthy volunteers and patients with acute coronary syndrome
Published in Platelets (Edinburgh) (01-06-2011)“…Glycoprotein (GP) IIb-IIIa (αIIbβ3-integrin) is the central receptor of platelet aggregation. Activated GP IIb-IIIa binds fibrinogen or von Willebrand factor,…”
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9
Comparison of the size of membrane microparticles of different cellular origin by dynamic light scattering
Published in Doklady. Biochemistry and biophysics (01-09-2016)“…Size of membrane microparticles (MPs) from blood plasma and MPs produced in vitro by activated endothelial cells (ECs), monocytes, THP-1 monocytic cells,…”
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10
Platelet subpopulation bearing leukocyte specific antigen and tissue factor
Published in Doklady. Biochemistry and biophysics (01-11-2016)“…Platelets bearing leukocyte antigen CD45 were identified in the blood of patients with myocardial infarction (MI) and healthy donors by flow cytofluorimetry…”
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11
Mean platelet volume: Interrelation with platelet aggregation activity and glycoprotein IIb-IIIa and Ib expression levels
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-04-2014)“…Increased mean platelet volume (MPV) is an independent risk factor of thrombotic events in patients with cardiovascular diseases. Interactions of MPV with…”
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12
Spontaneous Platelet Aggregation in Patients with Acute Coronary Syndrome
Published in Bulletin of experimental biology and medicine (01-05-2013)“…Spontaneous platelet aggregation was evaluated in patients with acute coronary syndrome on days 1, 3-5, and 8-12 of the disease. On day 1, aggregation was…”
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Platelet aggregation upon acetylsalicylic acid and clopidogrel treatment and glycoprotein IIb/IIIa content in patients with acute coronary syndrome
Published in Kardiologiia (2011)“…Interaction between aggregating activity of platelets and glycoprotein (GP) IIb/IIIa (fibrinogen receptor) content on their surface was investigated in…”
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Interaction of wheat germ agglutinin and concanavalin A with platelets. Stimulation of platelet functional reactions and binding with membrane glycoproteins
Published in Biochemistry (Moscow) (01-06-1998)“…Effects of two lectins, wheat germ agglutinin (WGA) and concanavalin A (Con A), on platelet functional reactions and interaction of lectins with the platelet…”
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15
Variations of glycoprotein IIb–IIIa (αIIb/β3-integrin) content in healthy donors. The influence on platelet aggregation activity and efficacy of aspirin action
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-03-2009)“…The effects of content of a fibrinogen receptor, glycoprotein (GP) IIb–IIIa (αIIb/β3-integrin), GP IIIa genetic polymorphism (substitution Leu33Pro), and…”
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Assay of antigens of antiplatelet antibodies in patients with various thrombocytopenias
Published in Bulletin of experimental biology and medicine (01-05-1998)“…Sandwich enzyme-linked immunosorbent assay was developed for evaluation of target antigens reacting with antiplatelet auto- and alloantibodies. The method…”
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17
Immunoenzyme assay of glycocalicin, platelet glycoprotein Ib fragment. Evaluation of platelet turnover in circulation and differential diagnosis of thrombocytopenia
Published in Bulletin of experimental biology and medicine (01-10-1999)“…We propose a method for measurement of plasma glycocalicin, a fragment of platelet membrane glycoprotein Ib. The concentration of glycocalicin is elevated in…”
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18
Participation of IIb-IIIa glycoprotein in spontaneous platelet aggregation
Published in Bulletin of experimental biology and medicine (01-04-2007)“…In some patients with stable and unstable angina pectoris and in some donors without clinical manifestations of cardiovascular diseases and other pathologies,…”
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Von Willebrand factor and soluble P-selectin in patients with non ST-Elevation acute coronary syndrome during treatment with glycoprotein IIb/IIIa antagonist eptifibatide
Published in Kardiologiia (2007)“…Soluble P-selectin (marker of activation of platelets) and von Willebrand factor (marker of activation of endothelium) were measured in 44 patients with non…”
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Detection of an epitope specific for the dissociated form of glycoprotein IIIa of platelet membrane glycoprotein IIb-IIIa complex and its expression on the surface of adherent platelets
Published in British journal of haematology (01-10-1993)“…Glycoproteins (GPs) IIb and IIIa form a Ca(2+)-dependent complex in platelet membrane and change their conformation upon platelet activation and dissociation…”
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