Search Results - "Kharsany, Ayesha B.M."
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HIV Infection and AIDS in Sub-Saharan Africa: Current Status, Challenges and Opportunities
Published in The open AIDS journal (08-04-2016)“…Global trends in HIV infection demonstrate an overall increase in HIV prevalence and substantial declines in AIDS related deaths largely attributable to the…”
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Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Published in Science (American Association for the Advancement of Science) (03-09-2010)“…The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of…”
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Recently formed age-disparate partnerships are associated with elevated HIV-incidence among young women in South Africa
Published in AIDS (London) (01-01-2020)“…OBJECTIVE:Cross-sectional and cohort studies draw different conclusions on whether age-disparate partnerships increase HIV-acquisition risk for young women. We…”
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Population prevalence of sexually transmitted infections in a high HIV burden district in KwaZulu-Natal, South Africa: Implications for HIV epidemic control
Published in International journal of infectious diseases (01-09-2020)“…•The high prevalence of STIs provides compelling evidence for enhanced surveillance for STI control.•Prevalence of curable STIs was higher in the younger age…”
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Seroprevalence of hepatitis B virus: Findings from a population-based household survey in KwaZulu-Natal, South Africa
Published in International journal of infectious diseases (01-08-2019)“…•Hepatitis B virus (HBV) infection remains an important cause of morbidity and mortality.•Surveillance for HBV virus surface antigen (HBsAg) is an important…”
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Drug-Resistant TB, HIV and COVID-19 Co-Infection: Case Reviews from Kwa-Zulu Natal, South Africa
Published in Infection and drug resistance (31-12-2023)“…Coronavirus disease (COVID-19) potentially exacerbates drug-resistant tuberculosis (DR-TB). We describe the clinical presentation and outcomes of three…”
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Medical male circumcision and HIV prevention among men in Kwazulu-Natal, South Africa: A propensity score analysis
Published in Scientific African (01-03-2021)“…Epidemiological theory and many empirical studies support the hypothesis that there is a protective effect of medical male circumcision (MMC) against HIV…”
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Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection
Published in The New England journal of medicine (06-08-2015)Get full text
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Co-enrollment in multiple HIV prevention trials — Experiences from the CAPRISA 004 Tenofovir gel trial
Published in Contemporary clinical trials (01-05-2011)“…Abstract Background In settings where multiple HIV prevention trials are conducted in close proximity, trial participants may attempt to enroll in more than…”
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High prevalence of abnormal Pap smears among young women co-infected with HIV in rural South Africa - : implications for cervical cancer screening policies in high HIV prevalence populations
Published in South African medical journal (01-02-2007)“…To establish the relationship between HIV infection and cervical dysplasia in young women in rural South Africa. This cross-sectional study was conducted at a…”
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Exposure to comprehensive sexuality education in schools in South Africa: the implications on the uptake of HIV testing services among HIV positive adolescent girls
Published in AIDS care (09-07-2024)“…Comprehensive sexuality education (CSE) is seen as a key instrument through which to affect behaviour and improve sexual and reproductive health (SRH) outcomes…”
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Omicron infection enhances Delta antibody immunity in vaccinated persons
Published in Nature (London) (14-07-2022)“…The extent to which Omicron infection 1 – 9 , with or without previous vaccination, elicits protection against the previously dominant Delta (B.1.617.2)…”
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Clinical Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Rapid Antigen Tests During the Omicron Wave in South Africa
Published in The Journal of infectious diseases (17-10-2022)“…We evaluated the performance of nasal and nasopharyngeal Standard Q COVID-19 [coronavirus disease 2019] Ag tests (SD Biosensor) and the Panbio COVID-19 Ag…”
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Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries
Published in PloS one (24-04-2018)“…In light of the limited impact the syndromic management approach has had on the global sexually transmitted infection (STI) epidemic, we assessed a care model…”
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HIV incidence and associated risk factors in adolescent girls and young women in South Africa: A population-based cohort study
Published in PloS one (21-12-2022)“…In sub-Saharan Africa, high HIV incidence rates in adolescent girls and young women (AGYW) persist despite extensive HIV prevention efforts. A prospective…”
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Role of Schooling and Comprehensive Sexuality Education in Reducing HIV and Pregnancy Among Adolescents in South Africa
Published in Journal of acquired immune deficiency syndromes (1999) (01-07-2022)“…Comprehensive sexuality education (CSE) seeks to reduce risky sexual behaviour and subsequent incidence of unintended pregnancy and HIV among schoolgoing…”
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Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection
Published in The New England journal of medicine (06-08-2015)“…Herpes simplex virus type 2 infection is a common sexually transmitted infection worldwide. Strategies to decrease transmission are needed. In this report from…”
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Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study
Published in The lancet HIV (01-01-2017)“…Summary Background The incidence of HIV infection in young women in Africa is very high. We did a large-scale community-wide phylogenetic study to examine the…”
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HIV Risk Among Adolescent Girls and Young Women in Age-Disparate Partnerships: Evidence From KwaZulu-Natal, South Africa
Published in Journal of acquired immune deficiency syndromes (1999) (01-06-2018)“…BACKGROUND:Evidence on the role of age-disparate partnerships in high HIV-infection rates among young women in sub-Saharan Africa remains inconclusive. This…”
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Host genetic variation at a locus near CHD1L impacts HIV sequence diversity in a South African population
Published in Journal of virology (31-10-2023)“…It has been previously shown that genetic variants near on chromosome 1 are associated with reduced HIV VL in African populations. However, the impact of these…”
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