Search Results - "Kharitonov, SA"

Effects of aerosolized adenosine 5'-triphosphate vs adenosine 5'-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma by Basoglu, Ozen K, Pelleg, Amir, Essilfie-Quaye, Sarah, Brindicci, Caterina, Barnes, Peter J, Kharitonov, Sergei A

“…Extracellular adenosine 5'-triphosphate (ATP) causes neurogenic bronchoconstriction, inflammation, and coughs, and may play a mechanistic role in obstructive…”
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Clinical aspects of exhaled nitric oxide by Kharitonov, SA, Barnes, PJ

“…There has been intense research into the role nitric oxide (NO) plays in physiological and pathological mechanisms and its clinical significance in respiratory…”
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Changes in the dose of inhaled steroid affect exhaled nitric oxide levels in asthmatic patients by Kharitonov, SA, Yates, DH, Chung, KF, Barnes, PJ

“…An increased concentration of nitric oxide (NO) in the exhaled air of asthmatic patients may reflect inflammation of the airways, and exhaled NO may,…”
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Exhaled markers of pulmonary disease by KHARITONOV, Sergei A, BARNES, Peter J

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Exhaled nitric oxide from lung periphery is increased in COPD by Brindicci, C, Ito, K, Resta, O, Pride, N. B, Barnes, P. J, Kharitonov, S. A

“…Single constant flow exhaled nitric oxide (eNO) cannot distinguish between the sources of NO. The present study measured eNO at multiple expired flows (MEFeNO)…”
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Exhaled markers of inflammatory lung diseases: ready for routine monitoring? by Kharitonov, SA

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Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children by Kharitonov, S.A, Gonio, F, Kelly, C, Meah, S, Barnes, P.J

“…Airway inflammation in asthma is not measured routinely in clinical practice. Fractional exhaled nitric oxide (FE(NO)), a marker of airway inflammation, is…”
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Contrasting effects of ATP and adenosine on capsaicin challenge in asthmatic patients by Basoglu, Ozen K., MD, Pelleg, Amir, PhD, Kharitonov, Sergei A., MD, Barnes, Peter J., Master FRS

“…Abstract Background Adenosine 5’-triphosphate (ATP) stimulates pulmonary vagal slow conducting C-fibres and fast conducting Aδ-fibres with rapidly adapting…”
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8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy by Carpagnano, Giovanna E, Kharitonov, Sergei A, Resta, Onofrio, Foschino-Barbaro, Maria P, Gramiccioni, Enzo, Barnes, Peter J

“…Obstructive sleep apnea (OSA) is characterized by recurrent apnea during sleep that may compromise oxidative balance. Oxidative stress is increased in the…”
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Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD by Biernacki, W A, Kharitonov, S A, Barnes, P J

“…Background: Exacerbations are an important feature of chronic obstructive pulmonary disease (COPD), accounting for a large proportion of health care costs…”
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High levels of interleukin-6 in the exhaled breath condensate of patients with COPD by Bucchioni, Enrica, Kharitonov, Sergei A., Allegra, Luigi, Barnes, Peter J.

“…Background: Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation of the respiratory tract. Methods: We investigated the…”
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Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers by MONTUSCHI, Paolo, COLLINS, John V, CIABATTONI, Giovanni, LAZZERI, Nicola, CORRADI, Massimo, KHARITONOV, Sergei A, BARNES, Peter J

“…Most of the studies linking chronic obstructive pulmonary disease (COPD) with oxidative stress are in vitro, using invasive techniques, or measuring systemic…”
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Increased Leukotrienes in Exhaled Breath Condensate in Childhood Asthma by Csoma, Zsuzsanna, Kharitonov, Sergei A, Balint, Beatrix, Bush, Andrew, Wilson, Nicola M, Barnes, Peter J

“…Cysteinyl leukotrienes (cys-LTs; LTC4, LTD4, and LTE4) are generated predominantly by mast cells and eosinophils and induce airway smooth muscle contraction,…”
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Increased nitrotyrosine in exhaled breath condensate of patients with asthma by HANAZAWA, Toyoyuki, KHARITONOV, Sergei A, BARNES, Peter J

“…The reaction of nitric oxide (NO) and superoxide anions (O(2)(-)) in the airway results in the formation of peroxynitrite, a highly reactive oxidant species…”
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Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients by Carpagnano, Giovanna E, Kharitonov, Sergei A, Resta, Onofrio, Foschino-Barbaro, Maria P, Gramiccioni, Enzo, Barnes, Peter J

“…Obstructive sleep apnea (OSA) is characterized by repeated episodes of upper airways obstruction during sleep that result in episodes of hypoxia. An increase…”
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Increased 8-Isoprostane, a Marker of Oxidative Stress, in Exhaled Condensate of Asthma Patients by MONTUSCHI, PAOLO, CORRADI, MASSIMO, CIABATTONI, GIOVANNI, NIGHTINGALE, JULIA, KHARITONOV, SERGEI A, BARNES, PETER J

“…Oxidative stress has an important role in the pathogenesis of asthma. 8-Isoprostane is a prostaglandin (PG)-F2-like compound belonging to the F2 isoprostane…”
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Analysis of expired air for oxidation products by PAREDI, Paolo, KHARITONOV, Sergei A, BARNES, Peter J

“…Chronic inflammation is a critical feature of chronic obstructive pulmonary disease, cystic fibrosis, and asthma. This inflammation is associated with the…”
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Exhaled markers of inflammatory lung diseases: ready for routine monitoring? by Kharitonov, Sergei A

“…Assessing airway inflammation is important for investigating the underlying mechanisms of many lung diseases, including asthma and chronic obstructive…”
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Dose-dependent onset and cessation of action of inhaled budesonide on exhaled nitric oxide and symptoms in mild asthma by Kharitonov, S A, Donnelly, L E, Montuschi, P, Corradi, M, Collins, J V, Barnes, P J

“…Background: Dose dependent anti-inflammatory effects of inhaled corticosteroids in asthma are difficult to demonstrate in clinical practice. The…”
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Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma by Jatakanon, A, Lim, S, Kharitonov, S A, Chung, K F, Barnes, P J

“…BACKGROUND: Eosinophils in induced sputum and exhaled nitric oxide (NO) are currently used as non-invasive markers in the assessment of airway inflammation in…”
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