Search Results - "Kharechkina, Ekaterina S."
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Regulation of Mitochondrial Permeability Transition Pore Opening by Monovalent Cations in Liver Mitochondria
Published in International journal of molecular sciences (25-05-2023)“…The opening of the permeability transition pore (PTP) in mitochondria is a key event in the initiation of cell death in various pathologic states, including…”
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Pioglitazone Is a Mild Carrier-Dependent Uncoupler of Oxidative Phosphorylation and a Modulator of Mitochondrial Permeability Transition
Published in Pharmaceuticals (Basel, Switzerland) (14-10-2021)“…Pioglitazone (PIO) is an insulin-sensitizing antidiabetic drug, which normalizes glucose and lipid metabolism but may provoke heart and liver failure and…”
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Mitochondrial F-ATP Synthase Co-Migrating Proteins and Ca2+-Dependent Formation of Large Channels
Published in Cells (Basel, Switzerland) (07-10-2023)“…Monomers, dimers, and individual FOF1-ATP synthase subunits are, presumably, involved in the formation of the mitochondrial permeability transition pore (PTP),…”
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Dynamics of the permeability transition pore size in isolated mitochondria and mitoplasts
Published in The FASEB journal (01-08-2021)“…The size of the permeability transition pore (PTP) is accepted to be ≤1.5 kDa. However, different authors reported values from 650 to 4000 Da. The present…”
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Pyridine nucleotides regulate the superoxide anion flash upon permeabilization of mitochondrial membranes: An MCLA-based study
Published in Free radical biology & medicine (20-08-2018)“…The permeabilization of mitochondrial membranes via permeability transition pore opening or by the pore-forming peptide alamethicin causes a flash of…”
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Regulation of permeability transition pore opening in mitochondria by external NAD(H)
Published in Biochimica et biophysica acta. General subjects (01-05-2019)“…The opening of the permeability transition pore (PTP) in mitochondria plays a critical role in the pathogenesis of numerous diseases. Mitochondrial matrix…”
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