Search Results - "Khare Satyam, Leena"

Expression and heterodimerization of Type A and B Cholecystokinin Receptors in Gallbladder cancer by Chandra, Abhijit, Nigam, Jaya, Goel, Madhumati, Parmar, Devendra, Satyam, Leena Khare

“…Abstract only e15655 Background: Gallbladder cancer is the most common malignancy of the biliary tract and endemic in Northern India. The prognosis of…”
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Abstract 1144: Orally bioavailable SMARCA2 degraders with exceptional selectivity and potency by Abbineni, Chandrasekhar, Satyam, Leena Khare, Kuila, Bilash, Ettam, Ashok, Rawoof, Khaji Abdul, MR, Sreevidya, Dukare, Sandeep Vitthal, Gore, Suraj T., Nankar, Rakesh P., Ahuja, Vijay Kamal, KB, Charamanna, Goyal, Megha, Aithal, Kiran, DS, Samiulla, Mukherjee, Subhendu, Antony, Thomas, Giri, Sanjeev, Chelur, Shekar, Nellore, Kavitha, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta

“…Abstract Background: SMARCA2 (BRM) and SMARCA4 (BRG1) are two mutually exclusive DNA-dependent ATPases of the SWI/SNF complex, which function in mobilizing…”
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Abstract 1266: Discovery and preclinical evaluation of a novel covalent inhibitor of FABP5 for cancer therapy by Chikkanna, Dinesh, Satyam, Leena Khare, Pnaigrahi, Sunil Kumar, Khairnar, Vinayak, Pothuganti, Manoj, Kaza, Lakshmi Narayan, Kalidindi, Narasimha Raju, Nataraj, Vijaya Shankar, Gatta, Aditya Kiran, Krishnamurthy, Narasimha Rao, Patil, Sandeep, Samiulla, DS, Aithal, Kiran, Ahuja, Vijay Kamal, Tiwari, Nirbhay Kumar, Charamannna, KB, Pise, Pravin, Anthony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Chelur, Shekar, Samajdar, Susanta, Ramachandra, Murali

“…Abstract Dysregulated fatty acid metabolism is thought to be a hallmark of cancer, wherein fatty acids function both as an energy source and as signals for…”
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Antibacterial spectrum of human omentum and differential expression of beta defensins by Srivastava, Meenu, Chandra, Abhijit, Agarwal, Jyotsna, Rahul, Rahul, Nigam, Jaya, Parmar, Devendra, Satyam, Leena Khare

“…Background Human β defensins (hBD1 and hBD2) are cationic, cysteine-rich peptides and form an integral part of the mammalian innate immune system. hBD1 is…”
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A let-7 microRNA binding site polymorphism in the KRAS 3'UTR is associated with increased risk and reduced survival for gallbladder cancer in North Indian population by Kazmi, Hasan Raza, Chandra, Abhijit, Kumar, Saket, Satyam, Leena Khare, Gupta, Annapurna, Nigam, Jaya, Srivastava, Meenu, Mittal, Balraj

“…Gallbladder cancer is a lethal malignancy of hepato-biliary system with high incidence in North India, especially along gangetic plain. The let-7 microRNAs…”
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A let-7 microRNA binding site polymorphism in the KRAS 3′UTR is associated with increased risk and reduced survival for gallbladder cancer in North Indian population by Kazmi, Hasan Raza, Chandra, Abhijit, Kumar, Saket, Satyam, Leena Khare, Gupta, Annapurna, Nigam, Jaya, Srivastava, Meenu, Mittal, Balraj

“…Purpose Gallbladder cancer is a lethal malignancy of hepato-biliary system with high incidence in North India, especially along gangetic plain. The let - 7…”
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Abstract 3844: Anti-tumor efficacy of SMARCA degraders in pre-clinical models of cancer by Satyam, Leena Khare, Sasmal, Sanjita, Pothuganti, Manoj K., M.R., Sreevidya, Ettam, Ashokk, Nunna, Sireesha, Roshaiah, Marla, Chithaluru, Shankaraiah, Pallepati, Rangarao, Pawar, Amitkumar A., Narukulla, Leela P., Sripathi, Raghunadh A., Tgore, Suraj, Nankar, Rakesh P., KB, Charamanna, S, Nagesh Gowda, Aithal, Kiran, DS, Samiulla, Mukherjee, Subhendu, Chelur, Shekar, Nellore, Kavitha, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta

“…Abstract SMARCA2/BRM and SMARCA4/BRG1 are the mutually exclusive DNA-dependent ATPases within the SWI/SNF complexes, which function in mobilizing nucleosomes…”
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Abstract 5108: Potent small molecule compounds that selectively inhibit proliferation of ABC-DLBCL cell lines by Satyam, Leena Khare, Chikkanna, Dinesh, Khairnar, Vinayak, Pothuganti, Manoj, Panigrahi, Sunil, Lakshminarasimhan, Anirudha, Rao, Narasimha, Balasubramanian, Wesley, Patil, Sandeep, Gopinath, Sreevalsam, Upendra, Gunta, Nagaraj, Jwala, Aithal, Kiran, Ahuja, Vijay, Giri, Sanjeev, Pandit, Chetan, Ramachandra, Murali

“…Abstract Diffuse large B cell lymphoma (DLBCL), which accounts for 25% of all lymphomas cases, has been classified into molecular subtypes including germinal…”
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Abstract B164: Identification of a novel highly selective and orally bioavailable preclinical candidate for CDK7 covalent inhibition by Poddutoori, Ramulu, Khare Satyam, Leena, Mukherjee, Subhendu, Marappan, Sivapriya, Gopinath, Sreevalsam, KB, Charamanna, Kaza, Lakshmi Narayana, Pothuganti, Manoj Kumar, Rajagopalan, Sujatha, Sivakumar, Sasirekha, E N, Bharath, A B, Aravind, A, Amith, M V, Ravindra, Tgore, Suraj, Antony, Thomas, Pandit, Chetan, Chelur, Shekar, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta

“…Abstract Background: Cyclin-dependent kinase 7 (CDK7) is an important constituent of the cellular transcriptional machinery, where it phosphorylates the…”
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Abstract 3070: Potent and selective inhibition of CDK7 by novel covalent inhibitors by Satyam, Leena Khare, Poddutoori, Ramulu, Mukherjee, Subhendu, Marappan, Sivapriya, Gopinath, Sreevalsam, Ramachandra, Raghuveer, Pothuganti, Manoj Kumar, Nayak, Shilpa S., C, Nandish, Naik, Chandranath, MV, Ravindra, Dabbeeru, Madhu B., A, Nagaraju, B, Mahankali, Antony, Thomas, Pandit, Chetan, Chelur, Shekar, Daginakatte, Girish, Samajdar, Susanta, Ramachandra, Murali

“…Abstract Background: Phosphorylation of the RNA polymerase II (RNAPII) in C-terminal domain (CTD) by Cyclin-dependent kinase 7 (CDK7) is an important step in…”
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Abstract 339: Identification of novel covalent inhibitors of K-Ras G12C that are efficacious in a xenograft model of NSCLC by Satyam, Leena Khare, Chikkanna, Dinesh, G, Aswani K., Khairnar, Vinayak V., Reddy, Sreekanth, Durgaprasad, Vakkapatla, Radhakrishna, Kowju, Panigrahi, Sunil K., Ramanathan, Anuradha, Mahasweta, Kumari, Lakshminarasimhan, Anirudha, K, Narasimha R., R, Vinutha, Gopinath, Sreevalsam, Kumar, Suryakant, Shah, Mubarak H., Ramachandra, Raghuveer, B, Kiran A., Pandit, Chetan, Ramachandra, Murali

“…Abstract KRAS is the frequently mutated isoform in RAS driven cancers. The G12C mutation is more predominantly associated with various tumor types over other…”
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