Search Results - "Khanna, Vinay K."

Serum vascular endothelial growth factor is a biomolecular biomarker of severity of diabetic retinopathy by Ahuja, Sukriti, Saxena, Sandeep, Akduman, Levent, Meyer, Carsten H, Kruzliak, Peter, Khanna, Vinay K

“…Elevated serum vascular endothelial growth factor (VEGF) levels are associated with diabetic retinopathy (DR). Serum VEGF levels correlate with vitreous…”
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Unraveling the mechanism of neuroprotection of curcumin in arsenic induced cholinergic dysfunctions in rats by Srivastava, Pranay, Yadav, Rajesh S., Chandravanshi, Lalit P., Shukla, Rajendra K., Dhuriya, Yogesh K., Chauhan, Lalit K.S., Dwivedi, Hari N., Pant, Aditiya B., Khanna, Vinay K.

“…Earlier, we found that arsenic induced cholinergic deficits in rat brain could be protected by curcumin. In continuation to this, the present study is focused…”
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Neuroprotective efficacy of curcumin in arsenic induced cholinergic dysfunctions in rats by Yadav, Rajesh S., Chandravanshi, Lalit P., Shukla, Rajendra K., Sankhwar, Madhu L., Ansari, Reyaz W., Shukla, Pradeep K., Pant, Aditya B., Khanna, Vinay K.

“…► Neuroprotective potential of curcumin in arsenic induced cholinergic deficits demonstrated in rats. ► Arsenic decreased learning activity associated with…”
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Early life arsenic exposure and brain dopaminergic alterations in rats by Chandravanshi, Lalit P., Shukla, Rajendra K., Sultana, Sarwat, Pant, Aditya B., Khanna, Vinay K.

“…•Impact of early life arsenic exposure investigated on brain dopaminergic alterations.•Arsenic increased DA-D2 receptors in corpus striatum associated with…”
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Ischemic insult induced apoptotic changes in PC12 cells: Protection by trans resveratrol by Agrawal, Megha, Kumar, Vivek, Kashyap, Mahendra P., Khanna, Vinay K., Randhawa, Gursharn S., Pant, Aditya B.

“…In this study, we determined the protective potential of trans resveratrol against oxygen–glucose deprivation (OGD) induced reactive oxygen species mediated…”
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trans-Resveratrol Protects Ischemic PC12 Cells by Inhibiting the Hypoxia Associated Transcription Factors and Increasing the Levels of Antioxidant Defense Enzymes by Agrawal, Megha, Kumar, Vivek, Singh, Abhishek K, Kashyap, Mahendra P, Khanna, Vinay K, Siddiqui, Maqsood A, Pant, Aditya B

“…An in vitro model of ischemic cerebral stroke [oxygen-glucose deprivation (OGD) for 6 h followed by 24 h reoxygenation (R)] with PC12 cells increases Ca2+…”
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Monocrotophos induces the expression and activity of xenobiotic metabolizing enzymes in pre-sensitized cultured human brain cells by Tripathi, Vinay K, Kumar, Vivek, Singh, Abhishek K, Kashyap, Mahendra P, Jahan, Sadaf, Pandey, Ankita, Alam, Sarfaraz, Khan, Feroz, Khanna, Vinay K, Yadav, Sanjay, Lohani, Mohtshim, Pant, Aditya B

“…The expression and metabolic profile of cytochrome P450s (CYPs) is largely missing in human brain due to non-availability of brain tissue. We attempted to…”
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M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera by Konar, Arpita, Gupta, Richa, Shukla, Rajendra K., Maloney, Bryan, Khanna, Vinay K., Wadhwa, Renu, Lahiri, Debomoy K., Thakur, Mahendra K.

“…Memory loss is one of the most tragic symptoms of Alzheimer’s disease. Our laboratory has recently demonstrated that ‘i-Extract’ of Ashwagandha ( Withania…”
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PI3K/Akt/GSK3β induced CREB activation ameliorates arsenic mediated alterations in NMDA receptors and associated signaling in rat hippocampus: Neuroprotective role of curcumin by Srivastava, Pranay, Dhuriya, Yogesh K., Kumar, Vivek, Srivastava, Akriti, Gupta, Richa, Shukla, Rajendra K., Yadav, Rajesh S., Dwivedi, Hari N., Pant, Aditya B., Khanna, Vinay K.

“…•Protective role of curcumin in arsenic induced NMDA receptor alterations investigated.•Sodium arsenite decreased expression of BDNF, pAkt, pErk ½, pGSK3β and…”
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Status of serum VEGF and ICAM-1 and its association with external limiting membrane and inner segment-outer segment junction disruption in type 2 diabetes mellitus by Jain, Astha, Saxena, Sandeep, Khanna, Vinay K, Shukla, Rajendra K, Meyer, Carsten H

“…To correlate the serum levels of vascular endothelial growth factor (VEGF) and intercellular adhesion molecule-1 (ICAM-1) with the severity of retinopathy and…”
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Nitric oxide and oxidative stress is associated with severity of diabetic retinopathy and retinal structural alterations by Sharma, Shashi, Saxena, Sandeep, Srivastav, Khushboo, Shukla, Rajendra K, Mishra, Nibha, Meyer, Carsten H, Kruzliak, Peter, Khanna, Vinay K

“…Background The aim of the study was to determine plasma nitric oxide (NO) and lipid peroxide (LPO) levels in diabetic retinopathy and its association with…”
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Beta-cyfluthrin induced neurobehavioral impairments in adult rats by Syed, Farah, Chandravanshi, Lalit P., Khanna, Vinay K., Soni, Inderpal

“…Beta-cyfluthrin (CYF) is a commonly used synthetic pyrethroid having both agricultural and domestic applications. The present study aimed to evaluate the…”
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Protective effect of Acorus calamus against acrylamide induced neurotoxicity by Shukla, Pradeep K., Khanna, Vinay K., Ali, M. M., Maurya, R. R., Handa, S. S., Srimal, R. C.

“…Exposure of rats to acrylamide (ACR) caused hind limb paralysis in 58% of the animals on day 10 and decreased behavioural parameters, namely distance…”
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Protective Effect of Curcumin by Modulating BDNF/DARPP32/CREB in Arsenic-Induced Alterations in Dopaminergic Signaling in Rat Corpus Striatum by Srivastava, Pranay, Dhuriya, Yogesh K., Gupta, Richa, Shukla, Rajendra K., Yadav, Rajesh S., Dwivedi, Hari N., Pant, Aditya B., Khanna, Vinay K

“…Earlier, protective role of curcumin in arsenic-induced dopamine (DA)–D2 receptor dysfunctions in corpus striatum has been demonstrated by us. In continuation…”
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Involvement of PKA/DARPP-32/PP1α and β- arrestin/Akt/GSK-3β Signaling in Cadmium-Induced DA-D2 Receptor-Mediated Motor Dysfunctions: Protective Role of Quercetin by Gupta, Richa, Shukla, Rajendra K., Pandey, Ankita, Sharma, Tanuj, Dhuriya, Yogesh K., Srivastava, Pranay, Singh, Manjul P., Siddiqi, Mohammad Imran, Pant, Aditya B., Khanna, Vinay K.

“…Given increasing risk of cadmium-induced neurotoxicity, the study was conducted to delineate the molecular mechanisms associated with cadmium-induced motor…”
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Protective Role of Quercetin in Cadmium-Induced Cholinergic Dysfunctions in Rat Brain by Modulating Mitochondrial Integrity and MAP Kinase Signaling by Gupta, Richa, Shukla, Rajendra K., Chandravanshi, Lalit P., Srivastava, Pranay, Dhuriya, Yogesh K., Shanker, Jai, Singh, Manjul P., Pant, Aditya B., Khanna, Vinay K.

“…With the increasing evidences of cadmium-induced cognitive deficits associated with brain cholinergic dysfunctions, the present study aimed to decipher…”
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Increased serum level of homocysteine correlates with retinal nerve fiber layer thinning in diabetic retinopathy by Srivastav, Khushboo, Saxena, Sandeep, Mahdi, Abbas A, Shukla, Rajendra K, Meyer, Carsten H, Akduman, Levent, Khanna, Vinay K

“…To study the correlation between serum levels of vitamin B , folic acid, and homocysteine and the severity of diabetic retinopathy and the correlation with…”
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Attenuation of arsenic neurotoxicity by curcumin in rats by Yadav, Rajesh S., Sankhwar, Madhu Lata, Shukla, Rajendra K., Chandra, Ramesh, Pant, Aditya B., Islam, Fakhrul, Khanna, Vinay K.

“…In view of continued exposure to arsenic and associated human health risk including neurotoxicity, neuroprotective efficacy of curcumin, a polyphenolic…”
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Association of serum N(ε)-Carboxy methyl lysine with severity of diabetic retinopathy by Mishra, Nibha, Saxena, Sandeep, Shukla, Rajendra K, Singh, Vinita, Meyer, Carsten H, Kruzliak, Peter, Khanna, Vinay K

“…To correlate serum levels of N-epsilon-carboxy methyl lysine (N(ε)-CML) with severity of retinopathy, in vivo macular edema and disruption of external limiting…”
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Increased serum urea and creatinine levels correlate with decreased retinal nerve fibre layer thickness in diabetic retinopathy by Srivastav, Khushboo, Saxena, Sandeep, Mahdi, Abbas A., Kruzliak, Peter, Khanna, Vinay K.

“…Correlation of increased levels of serum urea and creatinine with retinal nerve fibre layer (RNFL) thinning on spectral domain optical coherence tomography…”
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