Search Results - "Khani, Sajjad"
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LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat
Published in Nature communications (06-09-2018)“…Increasing brown adipose tissue (BAT) thermogenesis in mice and humans improves metabolic health and understanding BAT function is of interest for novel…”
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Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard
Published in Cell death & disease (10-08-2024)“…Sulfur mustard (SM) is a highly toxic chemical warfare agent. Exposure to SM results in various pathologies including skin lesions with subsequent impaired…”
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3
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling
Published in Diabetologia (01-08-2021)“…Aims/hypothesis Adipocytes are critical cornerstones of energy metabolism. While obesity-induced adipocyte dysfunction is associated with insulin resistance…”
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Nanopore sequencing unveils the complexity of the cold-activated murine brown adipose tissue transcriptome
Published in iScience (18-08-2023)“…Alternative transcription increases transcriptome complexity by expression of multiple transcripts per gene. Annotation and quantification of transcripts using…”
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Comprehensive Transcriptional Profiling and Mouse Phenotyping Reveals Dispensable Role for Adipose Tissue Selective Long Noncoding RNA Gm15551
Published in Non-coding RNA (06-05-2022)“…Cold and nutrient-activated brown adipose tissue (BAT) is capable of increasing systemic energy expenditure via the uncoupled respiration and secretion of…”
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Rapid Generation of Long Noncoding RNA Knockout Mice Using CRISPR/Cas9 Technology
Published in Non-coding RNA (23-01-2019)“…In recent years, long noncoding RNAs (lncRNAs) have emerged as multifaceted regulators of gene expression, controlling key developmental and disease…”
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Isolation and Molecular Identification of Streptomyces spp. with Antibacterial Activity from Northwest of Iran
Published in Bioimpacts (01-01-2013)“…[...]in this study different soil samples considering their pH value and altitude of locations were obtained from all around northwest of Iran and subjected to…”
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Expression Levels of PPARγ and CYP-19 in Polycystic Ovarian Syndrome Primary Granulosa Cells: Influence of ω-3 Fatty Acid
Published in International journal of fertility & sterility (01-07-2015)“…The omega-3 fatty acid (ω-3 fatty acid) such as eicosapentaenoic acid (EPA) is currently used in the clinic as a nutritional supplement in the treatment of…”
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Microsurgeon Hirudo medicinalis as a Natural Bioshuttle for Spontaneous Mass Vaccination against Influenza A Virus
Published in Bioimpacts (01-01-2011)“…Introduction: Recent report on existence of a stem region of hemagglutinin has arisen new hopes for vaccination of influenza A as it consist of a conserve…”
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Prevalence of virulent Yersinia enterocolitica in bulk raw milk and retail cheese in northern-west of Iran
Published in International journal of food microbiology (02-04-2012)“…To determine the prevalence of virulent Yersinia enterocolitica, 554 samples consisting of 354 bulk raw milks and 200 traditional cheeses were collected from…”
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Gap Junctions: The Claymore for Cancerous Cells
Published in Bioimpacts (01-01-2011)“…Introduction: Gap junctions play an important role in the cell proliferation in mammalian cells as well as carcinogenesis. However, there are controversial…”
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12
Cloning of taxadiene synthase gene into Arabidopsis thaliana (ecotype Columbia-0)
Published in African journal of biotechnology (22-03-2010)“…Paclitaxel (Taxol), a complex diterpenoid, produced by yew tree (Taxus sp.) is the most important chemotherapeutic agent that is widely used against a variety…”
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Fate of Yersinia enterocolitica during manufacture, ripening and storage of Lighvan cheese
Published in International journal of food microbiology (15-05-2012)“…This study aimed to evaluate the behavior of virulent Yersinia enterocolitica (YE) during the manufacture, ripening and storage of Lighvan cheese with…”
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Tracking of Mycobacterium Avium Paratuberculosis Load in Milk Production Chain: A Real-Time qPCR And Culture Assay
Published in Journal of food safety (01-02-2016)“…ABSTRACT Mycobacterium avium subsp. paratuberculosis (Map) is the causative agent of Johne's disease in ruminants and may contribute to Crohn's disease in…”
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Methylglyoxal Drives a Distinct, Nonclassical Macrophage Activation Status
Published in Thrombosis and haemostasis (01-11-2021)“…Metabolic complications in diabetic patients are driven by a combination of increased levels of nutrients and the presence of a proinflammatory environment…”
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The effect of the educational intervention on empowerment of male high school students in prevention of smoking
Published in Journal of substance use (04-03-2022)“…The present study aimed to investigate the effect of the educational intervention on empowerment of male high school students in the prevention of smoking…”
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Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques
Published in Cardiovascular research (17-03-2023)“…Abstract Aims Atherosclerosis is a chronic inflammatory disease of the arteries leading to the formation of atheromatous plaques. Human mesenchymal stem cells…”
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Multifunctional mitoxantrone-conjugated magnetic nanosystem for targeted therapy of folate receptor-overexpressing malignant cells
Published in Journal of nanobiotechnology (26-03-2015)“…Targeted delivery of anticancer chemotherapeutics such as mitoxantrone (MTX) can significantly intensify their cytotoxic effects selectively in solid tumors…”
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Dicer1–miR-328–Bace1 signalling controls brown adipose tissue differentiation and function
Published in Nature cell biology (01-03-2016)“…Kornfeld and colleagues identify miRNAs that are dysregulated in brown adipose tissue in mouse models of obesity and ageing, and show that miR-328 targets…”
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Quantitative real-time PCR and culture examination of Mycobacterium avium subsp. paratuberculosis at farm level
Published in Veterinary microbiology (22-02-2013)“…Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease in ruminants and may contribute to Crohn's disease in humans. The aim of this study…”
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