Search Results - "Khandekar, Janardan"

Clinical characteristics and viral load dynamics of COVID-19 in a mildly or moderately symptomatic outpatient sample by Caplan, Amanda, Bates, Kelly W, Brioni, Carla, Santos, Aileen, Sabatini, Linda M, Kaul, Karen L, Carnethon, Mercedes R, Khandekar, Janardan D, Greenland, Philip

“…Background Studies of outpatients with mild or moderate COVID-19 are uncommon. We studied: 1) association of symptoms with reverse transcriptase polymerase…”
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The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors by Bommi, Prashant V., Dimri, Manjari, Sahasrabuddhe, Anagh A., Khandekar, Janardan, Dimri, Goberdhan P.

“…Polycomb group (PcG) proteins are overexpressed in several human malignancies including breast cancer.  In particular, aberrant expression of BMI1 and EZH2 has…”
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Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells by Dimri, Manjari, Bommi, Prashant V., Sahasrabuddhe, Anagh A., Khandekar, Janardan D., Dimri, Goberdhan P.

“…The polycomb group (PcG) protein, enhancer of zeste homologue 2 (EZH2), is overexpressed in several human malignancies including breast cancer. Aberrant…”
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Value of Personalized Medicine by Dunnenberger, Henry M, Khandekar, Janardan D

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Double‐blind, randomized phase 3 trial of low‐dose 13‐cis retinoic acid in the prevention of second primaries in head and neck cancer: Long‐term follow‐up of a trial of the Eastern Cooperative Oncology Group‐ACRIN Cancer Research Group (C0590) by Bhatia, Aarti K., Lee, Ju‐Whei, Pinto, Harlan A., Jacobs, Charlotte D., Limburg, Paul J., Rubin, Philip, Arusell, Robert M., Dunphy, Eamonn P., Khandekar, Janardan D., Reiner, Seth A., Baez‐Diaz, Luis, Celano, Paul, Li, Shuli, Li, Yi, Burtness, Barbara A., Adams, George L., Pandya, Kishan J.

“…BACKGROUND 13‐Cis retinoic acid (13‐CRA) is a synthetic vitamin A derivative. High‐dose 13‐CRA in patients with squamous cell cancers of the head and neck…”
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Personalized medicine in a community health system: the NorthShore experience by David, Sean P, Dunnenberger, Henry M, Choi, Sarah, DePersia, Allison, Ilbawi, Nadim, Ward, Christopher, Wake, Dyson T, Khandekar, Janardan D, Shannon, Yvette, Hughes, Kristen, Miller, Nicholas, Mangold, Kathy A, Sabatini, Linda M, Helseth, Donald L, Xu, Jianfeng, Sanders, Alan, Kaul, Karen L, Hulick, Peter J

“…Genomic and personalized medicine implementation efforts have largely centered on specialty care in tertiary health systems. There are few examples of fully…”
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Cancer-associated thrombosis by cancer sites and inherited factors in a prospective population-based cohort by Shi, Zhuqing, Wei, Jun, Rifkin, Andrew S., Wang, Chi-Hsiung, Billings, Liana K., Woo, Jonathan S.H., Talamonti, Mark S., Vogel, Tilley Jenkins, Moore, Elena, Brockstein, Bruce E., Khandekar, Janardan D., Dunnenberger, Henry M., Hulick, Peter J., Duggan, David, Zheng, S. Lilly, Lee, Cheong Jun, Helfand, Brian T., Tafur, Alfonso J., Xu, Jianfeng

“…Cancer-associated thrombosis (CAT) is common and associated with mortality. We estimated CAT rate by cancer sites and inherited factors among cancer patients…”
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Direct observation of genomic heterogeneity through local haplotyping analysis by Gulukota, Kamalakar, Helseth, Jr, Donald L, Khandekar, Janardan D

“…It has been an abiding belief among geneticists that multicellular organisms' genomes can be analyzed under the assumption that a single individual has a…”
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Prospective Analysis of Association Between Use of Statins or Other Lipid-Lowering Agents and Colorectal Cancer Risk by Simon, Michael S., MD, MPH, Rosenberg, Carol A., MD, Rodabough, Rebecca J., MS, Greenland, Phillip, MD, Ockene, Ira, MD, Roy, Hemant K., MD, Lane, Dorothy S., MD, MPH, Cauley, Jane A., DrPH, Khandekar, Janardan, MD

“…Purpose To determine whether 3-hydroxy-3-methylglutaryl coenzyme A inhibitors (statins) are associated with a decreased risk of colorectal cancer. Methods The…”
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APC Gene Testing for Familial Adenomatosis Polyposis by Roy, Hemant K, Khandekar, Janardan D

“…Although genomics is intended to revolutionize clinical medicine, to date its beneficial effects have been somewhat muted. The promise and perils of genomics…”
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Clinical characteristics and viral load dynamics of COVID-19 in a mildly or moderately symptomatic outpatient sample by Amanda Caplan, Kelly W Bates, Carla Brioni, Aileen Santos, Linda M Sabatini, Karen L Kaul, Mercedes R Carnethon, Janardan D Khandekar, Philip Greenland

“…BackgroundStudies of outpatients with mild or moderate COVID-19 are uncommon. We studied: 1) association of symptoms with reverse transcriptase polymerase…”
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Promotion of self-management for post treatment cancer survivors: evaluation of a risk-adapted visit by Rosenberg, Carol A., Flanagan, Carol, Brockstein, Bruce, Obel, Jennifer C., Dragon, Leon H., Merkel, Douglas E., Wade, Elaine L., Law, Teresa M., Khandekar, Janardan D., Hensing, Thomas A.

“…Purpose The LIFE Cancer Survivorship Program at NorthShore University HealthSystem provides risk-adapted visits (RAV) facilitated by an oncology nurse during…”
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The spectrum of vascular lesions in the mammary skin, including angiosarcoma, after breast conservation treatment for breast cancer by Sener, Stephen F, Milos, Steven, Feldman, Joseph L, Martz, Carole H, Winchester, David J, Dieterich, Mark, Locker, Gershon Y, Khandekar, Janardan D, Brockstein, Bruce, Haid, Max, Michel, Arthur

“…BACKGROUND: With the general acceptance of lumpectomy, axillary staging, and radiotherapy as local treatment for infiltrating breast cancer, an appreciation is…”
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Phase I Trial of Fixed Dose Rate Infusion Gemcitabine with Gefitinib in Patients with Pancreatic Carcinoma by Carneiro, Benedito A., Brand, Randall E., Fine, Elita, Knop, Richard H., Khandekar, Janardan D., Uhlig, William, Locker, Gershon Y.

“…Purpose: To determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of gemcitabine using a fixed dose rate infusion (FDRI) in…”
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Germline Mutations in ATM and BRCA1/2 Distinguish Risk for Lethal and Indolent Prostate Cancer and are Associated with Early Age at Death by Na, Rong, Zheng, S. Lilly, Han, Misop, Yu, Hongjie, Jiang, Deke, Shah, Sameep, Ewing, Charles M, Zhang, Liti, Novakovic, Kristian, Petkewicz, Jacqueline, Gulukota, Kamalakar, Helseth Jr, Donald L, Quinn, Margo, Humphries, Elizabeth, Wiley, Kathleen E, Isaacs, Sarah D, Wu, Yishuo, Liu, Xu, Zhang, Ning, Wang, Chi-Hsiung, Khandekar, Janardan, Hulick, Peter J, Shevrin, Daniel H, Cooney, Kathleen A, Shen, Zhoujun, Partin, Alan W, Carter, H. Ballentine, Carducci, Michael A, Eisenberger, Mario A, Denmeade, Sam R, McGuire, Michael, Walsh, Patrick C, Helfand, Brian T, Brendler, Charles B, Ding, Qiang, Xu, Jianfeng, Isaacs, William B

“…Abstract Background Germline mutations in BRCA1/2 and ATM have been associated with prostate cancer (PCa) risk. Objective To directly assess whether germline…”
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In Memoriam, Henry T. Lynch, MD by Sener, Stephen F., Khandekar, Janardan

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Implementation of a multidisciplinary pharmacogenomics clinic in a community health system by Dunnenberger, Henry M, Biszewski, Matthew, Bell, Gillian C, Sereika, Annette, May, Holley, Johnson, Samuel G, Hulick, Peter J, Khandekar, Janardan

“…The development and implementation of a multidisciplinary pharmacogenomics clinic within the framework of an established community-based medical genetics…”
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Outcomes after targeted treatment based on somatic tumor genetic testing for women with gynecologic cancers by Somasegar, Sahana, Hoppenot, Claire, Kuchta, Kristine, Sereika, Annette, Khandekar, Janardan, Rodriguez, Gustavo, Moore, Elena, Hurteau, Jean, Vogel, Tilley Jenkins

“…Molecular tumor profiling and next-generation sequencing are being increasingly utilized, but there are limited data on the therapeutic implications and…”
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Three program enhancements to advance population genetic screening in a community health system during 2020 by Hulick, Peter, Hammernik, Jared, Ilbawi, Nadim, Khandekar, Janardan, Lemke, Amy, Yu, Kristen, Dunnenberger, Henry

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eP556 - Three program enhancements to advance population genetic screening in a community health system during 2020 by Hulick, Peter, Hammernik, Jared, Ilbawi, Nadim, Khandekar, Janardan, Lemke, Amy, Yu, Kristen, Dunnenberger, Henry

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