Search Results - "Khandaker, G M"

Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions by Kappelmann, N, Lewis, G, Dantzer, R, Jones, P B, Khandaker, G M

“…Inflammatory cytokines are commonly elevated in acute depression and are associated with resistance to monoaminergic treatment. To examine the potential role…”
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Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies by Khandaker, G M, Zimbron, J, Lewis, G, Jones, P B

“…Disruption of foetal development by prenatal maternal infection is consistent with a neurodevelopmental model of schizophrenia. Whether specific prenatal…”
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Applying Mendelian randomization to appraise causality in relationships between smoking, depression and inflammation by Galan, D., Perry, B. I., Warrier, V., Davidson, C. C., Stupart, O., Easton, D., Khandaker, G. M., Murray, G. K.

“…Smoking, inflammation and depression commonly co-occur and may be mechanistically linked. However, key questions remain around the direction of association and…”
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A population-based longitudinal study of childhood neurodevelopmental disorders, IQ and subsequent risk of psychotic experiences in adolescence by Khandaker, G M, Stochl, J, Zammit, S, Lewis, G, Jones, P B

“…Schizophrenia has a neurodevelopmental component to its origin, and may share overlapping pathogenic mechanisms with childhood neurodevelopmental disorders…”
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Early motor developmental milestones and schizophrenia: A systematic review and meta-analysis by Filatova, S, Koivumaa-Honkanen, H, Hirvonen, N, Freeman, A, Ivandic, I, Hurtig, T, Khandaker, GM, Jones, PB, Moilanen, K, Miettunen, J

“…Abstract The neurodevelopmental hypothesis of schizophrenia proposes that impaired brain development is a cause of the illness. Early motor developmental…”
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Clinical and sociodemographic comparison of people at high-risk for psychosis and with first-episode psychosis by Zimbrón, J., Ruiz de Azúa, S., Khandaker, G. M., Gandamaneni, P. K., Crane, C. M., González-Pinto, A., Stochl, J., Jones, P. B., Pérez, J.

“…Zimbrón J, Ruiz de Azúa S, Khandaker GM, Gandamaneni PK, Crane CM, González‐Pinto A, Stochl J, Jones PB, Pérez J. Clinical and sociodemographic comparison of…”
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Childhood inflammatory markers and intelligence as predictors of subsequent persistent depressive symptoms: a longitudinal cohort study by Khandaker, G M, Stochl, J, Zammit, S, Goodyer, I, Lewis, G, Jones, P B

“…To identify developmental sub-groups of depressive symptoms during the second decade of life, a critical period of brain development, using data from a…”
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Mood, anxiety and psychotic phenomena measure a common psychopathological factor by Stochl, J, Khandaker, G M, Lewis, G, Perez, J, Goodyer, I M, Zammit, S, Sullivan, S, Croudace, T J, Jones, P B

“…Psychotic phenomena are common in the general population but are excluded from diagnostic criteria for mild to moderate depression and anxiety despite their…”
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Insulin resistance and obesity, and their association with depression in relatively young people: findings from a large UK birth cohort by Perry, B I, Khandaker, G M, Marwaha, S, Thompson, A, Zammit, S, Singh, S P, Upthegrove, R

“…Depression frequently co-occurs with disorders of glucose and insulin homeostasis (DGIH) and obesity. Low-grade systemic inflammation and lifestyle factors in…”
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Childhood immuno-metabolic markers and risk of depression and psychosis in adulthood: A prospective birth cohort study by Donnelly, N.A., Perry, B.I., Jones, H.J., Khandaker, G.M.

“…Metabolic and inflammatory disorders commonly co-occur with depression and psychosis, with emerging evidence implicating immuno-metabolic dysfunction in their…”
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Cardiometabolic risk prediction algorithms for young people with psychosis: a systematic review and exploratory analysis by Perry, B. I., Upthegrove, R., Crawford, O., Jang, S., Lau, E., McGill, I., Carver, E., Jones, P. B., Khandaker, G. M.

“…Objective Cardiometabolic risk prediction algorithms are common in clinical practice. Young people with psychosis are at high risk for developing…”
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Childhood interleukin-6, C-reactive protein and atopic disorders as risk factors for hypomanic symptoms in young adulthood: a longitudinal birth cohort study by Hayes, J F, Khandaker, G M, Anderson, J, Mackay, D, Zammit, S, Lewis, G, Smith, D J, Osborn, D P J

“…There are no existing longitudinal studies of inflammatory markers and atopic disorders in childhood and risk of hypomanic symptoms in adulthood. This study…”
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Association between childhood infection, serum inflammatory markers and intelligence: findings from a population-based prospective birth cohort study by Mackinnon, N, Zammit, S, Lewis, G, Jones, P B, Khandaker, G M

“…A link between infection, inflammation, neurodevelopment and adult illnesses has been proposed. The objective of this study was to examine the association…”
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Does maternal body mass index during pregnancy influence risk of schizophrenia in the adult offspring? by Khandaker, G. M., Dibben, C. R. M., Jones, P. B.

“…Summary Maternal obesity in pregnancy has been linked with several adverse outcomes in offspring including schizophrenia. The rising prevalence of obesity may…”
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A comparison of the cumulative incidence and early risk factors for psychotic disorder in young adults in the Northern Finland Birth Cohorts 1966 and 1986 by Filatova, S., Marttila, R., Koivumaa-Honkanen, H., Nordström, T., Veijola, J., Mäki, P., Khandaker, G. M., Isohanni, M., Jääskeläinen, E., Moilanen, K., Miettunen, J.

“…Few studies have compared time trends for the incidence of psychosis. To date, the results have been inconsistent, showing a decline, an increase or no…”
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Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment by Khandaker, Golam M, Dr, Cousins, Lesley, DPhil, Deakin, Julia, PhD, Lennox, Belinda R, DM, Yolken, Robert, Prof, Jones, Peter B, Prof

“…Summary Complex interactions between the immune system and the brain might have important aetiological and therapeutic implications for neuropsychiatric brain…”
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Childhood infection and adult schizophrenia: A meta-analysis of population-based studies by Khandaker, Golam M, Zimbron, Jorge, Dalman, Christina, Lewis, Glyn, Jones, Peter B

“…Abstract Objective To determine whether exposures to infectious illness during childhood involving the CNS or elsewhere is associated with adult schizophrenia…”
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Parental inflammatory bowel disease and autism in children by Sadik, Aws, Dardani, Christina, Pagoni, Panagiota, Havdahl, Alexandra, Stergiakouli, Evie, Khandaker, Golam M., Sullivan, Sarah A., Zammit, Stan, Jones, Hannah J., Davey Smith, George, Dalman, Christina, Karlsson, Håkan, Gardner, Renee M., Rai, Dheeraj

“…Evidence linking parental inflammatory bowel disease (IBD) with autism in children is inconclusive. We conducted four complementary studies to investigate…”
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Assessment of the Role of IQ in Associations Between Population Density and Deprivation and Nonaffective Psychosis by Lewis, Gemma, Dykxhoorn, Jennifer, Karlsson, Håkan, Khandaker, Golam M, Lewis, Glyn, Dalman, Christina, Kirkbride, James B

“…Being born or raised in more densely populated or deprived areas is associated with increased risk of nonaffective psychosis in adulthood, but few studies to…”
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A novel biomarker of interleukin 6 activity and clinical and cognitive outcomes in depression by Foley, Éimear M., Slaney, Chloe, Donnelly, Nicholas A., Kaser, Muzaffer, Ziegler, Louise, Khandaker, Golam M.

“…Inflammatory cytokines like interleukin-6 (IL-6) are implicated in depression, but most studies have hitherto focused on circulating levels of IL-6 rather than…”
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