Search Results - "Khanam, Tasneem"
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Reconstructing clonal evolution in relapsed and non-relapsed Burkitt lymphoma
Published in Leukemia (01-02-2021)Get full text
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MOF-associated complexes ensure stem cell identity and Xist repression
Published in eLife (19-05-2014)“…Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently misregulated in cancers. Here, we study the regulatory…”
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Publisher Correction: Reconstructing clonal evolution in relapsed and non-relapsed Burkitt lymphoma
Published in Leukemia (01-12-2021)Get full text
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Poly(A)-Binding Protein Binds to A-Rich Sequences via RNA-Binding Domains 1+2 and 3+4
Published in RNA biology (01-10-2006)“…Poly(A) binding protein (PABP) binds non-protein-coding BC1 RNA and BC200 RNA, which contain adenosine-rich domains. Two combinations of the four PABP RNA…”
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Can ID repetitive elements serve as cis-acting dendritic targeting elements? An in vivo study
Published in PloS one (26-09-2007)“…Dendritic localization of mRNA/RNA involves interaction of cis-elements and trans-factors. Small, non-protein coding dendritic BC1 RNA is thought to regulate…”
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Structural insight into the binding mode of cefotaxime and meropenem to TEM-1, SHV-1, KPC-2, and Amp-C type beta-lactamases
Published in Cell biochemistry and biophysics (01-06-2024)“…Antimicrobial resistance is an emerging threat to public health around the world. The study employs computational and biophysical methods to investigate the…”
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Current status and future directions of T‐lymphoblastic lymphoma in children and adolescents
Published in British journal of haematology (01-05-2016)“…Summary The main challenges in the treatment of T‐cell lymphoblastic lymphoma (T‐LBL) in children and adolescents are twofold: to increase survival rates in…”
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Design of a targeted next‐generation DNA sequencing panel for pediatric T‐cell lymphoblastic lymphoma to unravel biology and optimize treatment
Published in Genes chromosomes & cancer (01-08-2022)“…Low incidence and molecular heterogeneity of pediatric T‐cell lymphoblastic lymphoma (T‐LBL) require an international, large‐scale effort to identify novel…”
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Integrative genomic analysis of pediatric T-cell lymphoblastic lymphoma reveals candidates of clinical significance
Published in Blood (29-04-2021)“…T-cell lymphoblastic lymphoma (T-LBL) is a heterogeneous malignancy of lymphoblasts committed to T-cell lineage. The dismal outcomes (15%-30%) after T-LBL…”
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Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma
Published in The Lancet. Haematology (01-03-2023)“…The European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) was established 25 years ago with the goal to facilitate clinical trials and research…”
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Inhibitory Effect of Naked Neural BC1 RNA or BC200 RNA on Eukaryotic in vitro Translation Systems is Reversed by Poly(A)-binding Protein (PABP)
Published in Journal of molecular biology (14-10-2005)“…Regulated protein biosynthesis in dendrites of neurons might be a key mechanism underlying learning and memory. Neuronal dendritic BC1 RNA and BC200 RNA and…”
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Poly(A)-binding Protein is Associated with Neuronal BC1 and BC200 Ribonucleoprotein Particles
Published in Journal of molecular biology (16-08-2002)“…BC1 RNA and BC200 RNA are two non-homologous, small non-messenger RNAs (snmRNAs) that were generated, evolutionarily, quite recently by retroposition. This…”
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The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice
Published in Molecular metabolism (Germany) (01-09-2014)“…Abstract Overfeeding causes rapid synaptic remodeling in hypothalamus feeding circuits. Polysialylation of cell surface molecules is a key step in this…”
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Two primate-specific small non-protein-coding RNAs in transgenic mice: neuronal expression, subcellular localization and binding partners
Published in Nucleic acids research (01-01-2007)“…In a rare occasion a single chromosomal locus was targeted twice by independent Alu-related retroposon insertions, and in both cases supported neuronal…”
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Serine 27, a Human Retinoid X Receptor α Residue, Phosphorylated by Protein Kinase A Is Essential for CyclicAMP-Mediated Downregulation of RXRα Function
Published in Biochemical and biophysical research communications (29-12-2000)“…Retinoid X Receptor α (RXRα), a member of the steroid-thyroid hormone receptor super family, is phosphorylated in vitro by protein kinase A (PKA) and this…”
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Transcriptional activation by hepatocyte nuclear factor-4 in a cell-free system derived from rat liver nuclei
Published in Nucleic acids research (01-03-2001)“…Hepatocyte nuclear factor-4 (HNF4) regulates gene expression by binding to direct repeat motifs of the RG(G/T)TCA sequence separated by one nucleotide (DR1)…”
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