Search Results - "Khanal, Santosh"
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1
Cross-reactive antibody immunity against SARS-CoV-2 in children and adults
Published in Cellular & molecular immunology (01-07-2021)Get full text
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Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination
Published in Scientific reports (20-04-2022)“…SARS-CoV-2 is a novel betacoronavirus that caused coronavirus disease 2019 and has resulted in millions of deaths worldwide. Novel coronavirus infections in…”
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Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals
Published in BMC medicine (26-07-2021)“…Abstract Background The global pandemic of coronavirus disease 2019 (COVID-19) is caused by infection with the SARS-CoV-2 virus. Currently, there are three…”
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A comparative assessment of conventional and molecular methods, including MinION nanopore sequencing, for surveying water quality
Published in Scientific reports (31-10-2019)“…Nucleic acid based techniques, such as quantitative PCR (qPCR) and next generation sequencing (NGS), provide new insights into microbial water quality, but…”
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Effect of Modified Cardanol as Secondary Plasticizer on Thermal and Mechanical Properties of Soft Polyvinyl Chloride
Published in ACS omega (21-07-2020)“…This study represents the first attempt to prepare a novel cardanol-based plasticizer. Modified cardanol (MC, i.e., phosphorylated cardanol) containing…”
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Dose response relationship between program attendance and children's outcomes in a community based weight management program for children and their families
Published in BMC public health (10-06-2019)“…The Go4Fun program in New South Wales, Australia is a community based weight management program for overweight and obese children aged 7-13 years and their…”
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Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome
Published in Cell reports (Cambridge) (12-11-2019)“…People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to the general population, including lower rates of solid malignancies…”
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Production, Characterization, and Industrial Application of Pectinase Enzyme Isolated from Fungal Strains
Published in Fermentation (Basel) (09-06-2020)“…Pectinases are the group of enzymes that catalyze the degradation of pectic substances. It has wide applications in food industries for the production and…”
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Using the knowns to discover the unknowns: MS‐based dereplication uncovers structural diversity in 17‐hydroxygeranyllinalool diterpene glycoside production in the Solanaceae
Published in The Plant journal : for cell and molecular biology (01-02-2016)“…Exploring the diversity of plant secondary metabolism requires efficient methods to obtain sufficient structural insights to discriminate previously known from…”
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Faecal pollution source tracking in the holy Bagmati River by portable 16S rRNA gene sequencing
Published in npj clean water (18-02-2021)“…A suitcase laboratory was used for 16S rRNA amplicon sequencing to assess microbial water quality in the holy Bagmati River, Kathmandu, Nepal. SourceTracker…”
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Preparing for success in final summative medical specialist examinations: The case for RACE
Published in BMC medical education (05-12-2023)“…Failure rates on medical specialist final summative examinations in Australia are high, regardless of speciality. Examination failure can have detrimental…”
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Evaluation of Get Healthy at Work, a state-wide workplace health promotion program in Australia
Published in BMC public health (13-02-2019)“…Workplace health programs (WHPs) may improve adult health but very little evidence exists on multi-level WHPs implemented at-scale and so the relationship…”
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Extended spectrum β-lactamase producing uropathogenic Escherichia coli and the correlation of biofilm with antibiotics resistance in Nepal
Published in Annals of clinical microbiology and antimicrobials (17-12-2019)“…Urinary tract infection (UTI) is one of the frequently diagnosed infectious diseases which is caused mainly by Escherichia coli. E. coli confers resistance…”
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Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy
Published in BMC immunology (29-09-2022)“…Cellular immune responses are phenotypically and functionally perturbed during HIV-1 infection, with the majority of function restored upon antiretroviral…”
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Sero-epidemiology study of leptospirosis in febrile patients from Terai region of Nepal
Published in BMC infectious diseases (18-09-2017)“…Leptospirosis is a re-emerging zoonotic disease caused by pathogenic strains of bacteria belonging to genus Leptospira whose symptoms can range from mild…”
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FAM193A is a positive regulator of p53 activity
Published in Cell reports (Cambridge) (28-03-2023)“…Inactivation of the p53 tumor suppressor, either by mutations or through hyperactivation of repressors such as MDM2 and MDM4, is a hallmark of cancer. Although…”
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Phytochemical analysis of medicinal plants of Nepal and their antibacterial and antibiofilm activities against uropathogenic Escherichia coli
Published in BMC complementary and alternative medicine (09-04-2021)“…A biofilm is an extracellular polymeric substance (EPS) composed of polysaccharides, proteins, nucleic acids, and lipids that impede antibiotics and immune…”
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Molecular Identification and Antimicrobial Potential of Streptomyces Species from Nepalese Soil
Published in International journal of microbiology (2020)“…Streptomyces are widely used for the production of secondary metabolites with diverse biological activities, including antibiotics. The necessity of…”
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“Well I Failed, but I Have No Idea Why”…: Experiences of Feedback After High-Stakes Summative Specialist Medical Examination in Ophthalmology
Published in Journal of medical education and curricular development (01-01-2024)“…OBJECTIVE Medical specialist trainees report dissatisfaction with both the usefulness and timing of feedback provided following summative examinations. This…”
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Nanoscale phase dynamics of the normal tear film
Published in Nanomedicine (01-12-2010)“…Abstract The tear film is a dynamic multilayered structure. The interactions and the interfacial dynamics between the layers that occur during a blink cycle…”
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