Search Results - "Khan, Zafar K"

Potential Role of Flavonoids in Treating Chronic Inflammatory Diseases with a Special Focus on the Anti-Inflammatory Activity of Apigenin by Ginwala, Rashida, Bhavsar, Raina, Chigbu, DeGaulle I, Jain, Pooja, Khan, Zafar K

“…Inflammation has been reported to be intimately linked to the development or worsening of several non-infectious diseases. A number of chronic conditions such…”
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Targeting the C-type lectins-mediated host-pathogen interactions with dextran by Pustylnikov, Sergey, Sagar, Divya, Jain, Pooja, Khan, Zafar K

“…Dextran, the α-1,6-linked glucose polymer widely used in biology and medicine, promises new applications. Linear dextran applied as a blood plasma substitute…”
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Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood-brain barrier through paracellular transmigration and ERK activation by Sagar, Divya, Lamontagne, Anne, Foss, Catherine A, Khan, Zafar K, Pomper, Martin G, Jain, Pooja

“…Transmigration of circulating dendritic cells (DCs) into the central nervous system (CNS) across the blood-brain barrier (BBB) has not thus far been…”
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Regulation of human T-cell leukemia virus type 1 antisense promoter by myocyte enhancer factor-2C in the context of adult T-cell leukemia and lymphoma by Madugula, Kiran K, Joseph, Julie, DeMarino, Catherine, Ginwala, Rashida, Teixeira, Vanessa, Khan, Zafar K, Sales, Dominic, Wilson, Sydney, Kashanchi, Fatah, Rushing, Amanda W, Lemasson, Isabelle, Harhaj, Edward W, Janakiram, Murali, Ye, B Hilda, Jain, Pooja

“…Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1)…”
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Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity by Sagar, Divya, Singh, Narendra P., Ginwala, Rashida, Huang, Xiaofang, Philip, Ramila, Nagarkatti, Mitzi, Nagarkatti, Prakash, Neumann, Konstantin, Ruland, Jürgen, Andrews, Allison M., Ramirez, Servio H., Khan, Zafar K., Jain, Pooja

“…The mechanism of dendritic cells (DCs) recruitment across the blood brain barrier (BBB) during neuroinflammation has been the least explored amongst all…”
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DC-SIGN Mediates Cell-Free Infection and Transmission of Human T-Cell Lymphotropic Virus Type 1 by Dendritic Cells by JAIN, Pooja, MANUEL, Sharrón L, KHAN, Zafar K, AHUJA, Jaya, QUANN, Kevin, WIGDAHL, Brian

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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HTLV-1 Tax mediated downregulation of miRNAs associated with chromatin remodeling factors in T cells with stably integrated viral promoter by Rahman, Saifur, Quann, Kevin, Pandya, Devanshi, Singh, Shruti, Khan, Zafar K, Jain, Pooja

“…RNA interference (RNAi) is a natural cellular mechanism to silence gene expression and is predominantly mediated by microRNAs (miRNAs) that target messenger…”
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Mechanisms of Dendritic Cell Trafficking Across the Blood–brain Barrier by Sagar, Divya, Foss, Catherine, El Baz, Rasha, Pomper, Martin G., Khan, Zafar K., Jain, Pooja

“…Although the central nervous system (CNS) is considered to be an immunoprivileged site, it is susceptible to a host of autoimmune as well as neuroinflammatory…”
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FDC:TFH Interactions within Cervical Lymph Nodes of SIV-Infected Rhesus Macaques by Dave, Rajnish S., Sharma, Ravi K., Muir, Roshell R., Haddad, Elias, Gumber, Sanjeev, Villinger, Francois, Nehra, Artinder P., Khan, Zafar K., Wigdahl, Brian, Ansari, Aftab A., Byrareddy, Siddappa N., Jain, Pooja

“…Cerebrospinal fluid (CSF) drains via the lymphatic drainage pathway. This lymphatic pathway connects the central nervous system (CNS) to the cervical lymph…”
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Presentation of human T cell leukemia virus type 1 (HTLV-1) Tax protein by dendritic cells: the underlying mechanism of HTLV-1-associated neuroinflammatory disease by Manuel, Sharrón L., Schell, Todd D., Acheampong, Edward, Rahman, Saifur, Khan, Zafar K., Jain, Pooja

“…DC function to prime anti‐Tax CTL response in presence of HTLV‐infected T cells, acute exposure to HTLV virions, or cell‐free Tax. HTLV‐1 is the etiologic…”
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Can Soluble Immune Checkpoint Molecules on Exosomes Mediate Inflammation? by Joseph, Julie, Rahmani, Benjamin, Cole, Yonesha, Puttagunta, Neha, Lin, Edward, Khan, Zafar K., Jain, Pooja

“…Immune checkpoints (ICPs) are major co-signaling pathways that trigger effector functions in immune cells, with isoforms that are either membrane bound,…”
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Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1 by Jain, Pooja, Ahuja, Jaya, Khan, Zafar K., Shimizu, Saori, Meucci, Olimpia, Jennings, Stephen R., Wigdahl, Brian

“…Human T cell leukemia virus type 1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is characterized by the generation of an intense CTL cell…”
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Identification of Human T Cell Leukemia Virus Type 1 Tax Amino Acid Signals and Cellular Factors Involved in Secretion of the Viral Oncoprotein by Jain, Pooja, Mostoller, Kate, Flaig, Katherine E., Ahuja, Jaya, Lepoutre, Veronique, Alefantis, Timothy, Khan, Zafar K., Wigdahl, Brian

“…Human T cell leukemia virus type 1 (HTLV-1) is the etiologic agent of a number of pathologic abnormalities, including adult T cell leukemia (ATL) and…”
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Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions by Ginwala, Rashida, McTish, Emily, Raman, Chander, Singh, Narendra, Nagarkatti, Mitzi, Nagarkatti, Prakash, Sagar, Divya, Jain, Pooja, Khan, Zafar K.

“…Apigenin, a natural flavonoid, found in several plants, fruits, vegetables, herbs, and spices, is known to have anti-oxidant and anti-inflammatory properties…”
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A novel high throughput quantum dot-based fluorescence assay for quantitation of virus binding and attachment by Kampani, Karan, Quann, Kevin, Ahuja, Jaya, Wigdahl, Brian, Khan, Zafar K., Jain, Pooja

“…Quantum dots (QDots) are fluorescent semiconductor nanocrystals with a narrow emission spectrum, high quantum yield, and excellent photostability. These unique…”
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Apigenin Modulates Dendritic Cell Activities and Curbs Inflammation Via RelB Inhibition in the Context of Neuroinflammatory Diseases by Ginwala, Rashida, Bhavsar, Raina, Moore, Patrick, Bernui, Mariana, Singh, Narendra, Bearoff, Frank, Nagarkatti, Mitzi, Khan, Zafar K., Jain, Pooja

“…Neuroinflammation leads to tissue injury causing many of the clinical symptoms of Multiple Sclerosis, an autoimmune disorder of the central nervous system…”
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Dendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle? by Sehgal, Mohit, Khan, Zafar K., Talal, Andrew H., Jain, Pooja

“…Persistent infections with human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) are a major cause of morbidity and mortality worldwide. As…”
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In vivo and in vitro immunogenicity of novel MHC class I presented epitopes to confer protective immunity against chronic HTLV-1 infection by Mulherkar, Ria, Karabudak, Aykan, Ginwala, Rashida, Huang, Xiaofang, Rowan, Aileen, Philip, Ramila, Murphy, Edward L., Clements, Danielle, Ndhlovu, Lishomwa C., Khan, Zafar K., Jain, Pooja

“…•HTLV-1 is a potentially seriously disabling virus for which there is currently no cure or vaccine.•Immunoproteomics can identify naturally presented epitopes…”
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Diminished TLR2-TLR9 mediated CD4+ T cell responses are associated with increased inflammation in intraocular tuberculosis by Sharma, Ravi Kumar, Sharma, Jyoti, Khan, Zafar K., Pattekar, Ajinkya, Gupta, Vishali, Bansal, Reema, Sharma, Kusum, Aggarwal, Ashutosh Nath, Gupta, Amod, Sachdeva, Naresh

“…Intraocular tuberculosis (IOTB) is amongst the leading causes of uveitis in tropical countries. Despite reports on involvement of proinflammatory cytokines,…”
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MEF-2 isoforms' (A-D) roles in development and tumorigenesis by Madugula, Kiran, Mulherkar, Ria, Khan, Zafar K, Chigbu, DeGaulle I, Patel, Dip, Harhaj, Edward W, Jain, Pooja

“…Myocyte enhancer factor (MEF)-2 plays a critical role in proliferation, differentiation, and development of various cell types in a tissue specific manner…”
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