Search Results - "Khan, Wasiuddin A."

Uranyl acetate-induced sensorimotor deficit and increased nitric oxide generation in the central nervous system in rats by Abou-Donia, Mohamed B, Dechkovskaia, Anjelika M, Goldstein, Larry B, Shah, Deepti U, Bullman, Sarah L, Khan, Wasiuddin A

“…We investigated the effects of uranyl acetate on sensorimotor behavior, generation of nitric oxide and the central cholinergic system of rats. Male…”
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In utero exposure to nicotine and chlorpyrifos alone, and in combination produces persistent sensorimotor deficits and Purkinje neuron loss in the cerebellum of adult offspring rats by ABOU-DONIA, Mohamed B, KHAN, Wasiuddin A, DECHKOVSKAIA, Anjelika M, GOLDSTEIN, Larry B, BULLMAN, Sarah L, ABDEL-RAHMAN, Ali

“…This study was carried out to investigate the effect of in utero exposure to the cholinotoxicants, nicotine and chlorpyrifos, alone or in combination on…”
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Valproic acid reduces the tolerability of temsirolimus in children and adolescents with solid tumors by Coulter, Don W, Walko, Christine, Patel, Jai, Moats-Staats, Billie M, McFadden, Andrew, Smith, Scott V, Khan, Wasiuddin A, Bridges, Arlene S, Deal, Allison M, Oesterheld, Javier, Davis, Ian J, Blatt, Julie

“…A pediatric study has established a maximum tolerated dose (MTD) for temsirolimus (Tem) of more than 150 mg/m intravenously/week. A phase I trial was conducted…”
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Co-exposure to pyridostigmine bromide, DEET, and/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity by Abou-Donia, Mohamed B, Dechkovskaia, Anjelika M, Goldstein, Larry B, Abdel-Rahman, Ali, Bullman, Sarah L, Khan, Wasiuddin A

“…Military personnel deployed in the Persian Gulf War (PGW) were exposed to a combination of chemicals, including pyridostigmine bromide (PB), DEET, and…”
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Maternal exposure of rats to nicotine via infusion during gestation produces neurobehavioral deficits and elevated expression of glial fibrillary acidic protein in the cerebellum and CA1 subfield in the offspring at puberty by Abdel-Rahman, Ali, Dechkovskaia, Anjelika M., Sutton, Jazmine M., Chen, Wei-Chung, Guan, Xiangrong, Khan, Wasiuddin A., Abou-Donia, Mohamed B.

“…Maternal smoking during pregnancy is known to be a significant contributor to developmental neurological health problems in the offspring. In animal studies,…”
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Locomotor and Sensorimotor Performance Deficit in Rats following Exposure to Pyridostigmine Bromide, DEET, and Permethrin, Alone and in Combination by Abou-Donia, Mohammed B., Goldstein, Larry B., Jones, Katherine H., Abdel-Rahman, Ali A., Damodaran, Tirupapuliyur V., Dechkovskaia, Anjelika M., Bullman, Sarah L., Amir, Belal E., Khan, Wasiuddin A.

“…Since their return from Persian Gulf War (PGW), many veterans have complained of symptoms including muscle and joint pain, ataxia, chronic fatigue, headache,…”
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Sensorimotor Deficit and Cholinergic Changes following Coexposure with Pyridostigmine Bromide and Sarin in Rats by Abou-Donia, Mohamed B., Dechkovskaia, Anjelika M., Goldstein, Larry B., Bullman, Sarah L., Khan, Wasiuddin A.

“…A myriad of neurological symptoms including muscle and joint pain, ataxia, chronic fatigue, headache, and difficulty in concentration have been reported by…”
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Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: Differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine by ABDEL-RAHMAN, Ali, DECHKOVSKAIA, Anjelika M, MEHTA-SIMMONS, Heena, XIANGRONG GUAN, KHAN, Wasiuddin A, ABOU-DONIA, Mohamed B

“…Cigarette smoking and environmental exposure to chlorpyrifos during pregnancy could lead to developmental toxicity in the offspring. In the present study,…”
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12(S)-Hydroxyeicosatetraenoic Acid and 13(S)-Hydroxyoctadecadienoic Acid Regulation of Protein Kinase C-α in Melanoma Cells: Role of Receptor-Mediated Hydrolysis of Inositol Phospholipids by Liu, Bin, Khan, Wasiuddin A., Hannun, Yusuf A., Timar, Jozsef, Taylor, John D., Lundy, Steven, Butovich, Igor, Honn, Kenneth V.

“…Protein kinase C (PKC) isoenzymes are essential components of cell signaling. In this study, we investigated the regulation of PKC-α in murine B16 amelanotic…”
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Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats by ABOU-DONIA, Mohamed B, ABDEL-RAHMAN, Ali, GOLDSTEIN, Larry B, DECHKOVSKAIA, Anjelika M, SHAH, Deepti U, BULLMAN, Sarah L, KHAN, Wasiuddin A

“…Despite well-known adverse effects associated with cigarette smoking, approximately 20% of the US population continues to smoke and many more are exposed to…”
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Maternal exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring in late puberty by ABDEL-RAHMAN, Ali, DECHKOVSKAIA, Anjelika M, MEHTA-SIMMONS, Heena, SUTTON, Jazmine M, XIANGRONG GUAN, KHAN, Wasiuddin A, ABOU-DONIA, Mohamed B

“…We previously showed that maternal exposure to nicotine, alone or in combination with chlorpyrifos, caused an increase in glial fibrillary acidic protein…”
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Testicular Germ-Cell Apoptosis in Stressed Rats Following Combined Exposure to Pyridostigmine Bromide, N , N -Diethyl m -Toluamide (Deet), and Permethrin by Abou-Donia, Mohamed, Suliman, Hagir, Khan, Wasiuddin, Abdel-Rahman, Ali

“…This study reports and characterizes the testicular apoptosis following daily exposure of male Sprague-Dawley rats to subchronic combined doses of…”
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Effect of dietary tannic acid on epidermal, lung, and forestomach polycyclic aromatic hydrocarbon metabolism and tumorigenicity in Sencar mice by Athar, M, Khan, W A, Mukhtar, H

“…Tannic acid inhibits the mutagenicity of several polycyclic aromatic hydrocarbons (PAHs) and their bay-region diol-epoxides. Our prior studies have shown that…”
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Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice by HASAN MUKHTAR, MUKUL DAS, KHAN, W. A, WANG, Z. Y, BIK, D. P, BICKERS, D. R

“…Our recent studies have shown that naturally occurring dietary plant phenols such as tannic acid, quercetin, myricetin, and anthraflavic acid are capable of…”
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SUBCHRONIC EFFECTS FOLLOWING A SINGLE SARIN EXPOSURE ON BLOOD-BRAIN AND BLOOD-TESTES BARRIER PERMEABILITY, ACETYLCHOLINESTERASE, AND ACETYLCHOLINE RECEPTORS IN THE CENTRAL NERVOUS SYSTEM OF RAT: A DOSE-RESPONSE STUDY by Jones, Katherine H., Dechkovskaia, Anjelika M., Herrick, Elizabeth A., Abdel-Rahman, Ali A., Khan, Wasiuddin A., Abou-Donia, Mohamed B.

“…Subchronic neurotoxic effects of sarin (O-isopropyl methylphosphonofluoridate) treatment at various doses in male Sprague Dawley rats were studied. The animals…”
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Inhibition of polycyclic aromatic hydrocarbon-DNA adduct formation in epidermis and lungs of SENCAR mice by naturally occurring plant phenols by MUKUL DAS, KHAN, W. A, PARTHASARATHY ASOKAN, BICKERS, D. R, HASAN MUKHTAR

“…Naturally occurring plant phenols such as tannic acid, quercetin, myricetin, and anthraflavic acid are known to inhibit the mutagenicity of several bay-region…”
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Valproic Acid Reduces the Tolerability of Temsirolimus in Children with Solid Tumors by Coulter, Don W., Walko, Christine, Patel, Jai, Moats-Staats, Billie M., McFadden, Andrew, Smith, Scott V., Khan, Wasiuddin A., Bridges, Arlene S., Deal, Allison M., Oesterheld, Javier, Davis, Ian J., Blatt, Julie

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Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C by Khan, Wasiuddin A., Blobe, Gerard C., Hannun, Yusuf A.

“…In addition to serving as the precursor to a plethora of eicosanoids and other bioactive molecules, arachidonate may function as a bona fide second messenger…”
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Tissue and Cellular Distribution of the Extended Family of Protein Kinase C Isoenzymes by Wetsel, William C., Khan, Wasiuddin A., Merchenthaler, Istvan, Rivera, Hector, Halpern, Andrew E., Phung, Hahn M., Negro-Vilar, Andrés, Hannun, Yusuf A.

“…Polyclonal isoenzyme-specific antisera were developed against four calcium-independent protein kinase C (PKC) isoenzymes (δ, ε, ε′, and ζ) as well as the…”
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Antimutagenic activity of green tea polyphenols by Wang, Z Y, Cheng, S J, Zhou, Z C, Athar, M, Khan, W A, Bickers, D R, Mukhtar, H

“…For centuries green tea has been a widely consumed beverage throughout the world. It is known to contain a number of pharmacologically active compounds. In…”
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