Search Results - "Khan, Wahid Ali"
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Recombinant interferon alpha 2b in rheumatoid arthritis: good antigen for rheumatoid arthritis antibodies
Published in Central-European journal of immunology (2018)“…Interferon alpha-induced arthritis and activation of the type 1 interferon pathway during rheumatoid arthritis (RA) has been well documented but the underlying…”
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2
Endometrial cancer patients have high affinity antibodies for estrogen metabolite–receptor aggregate: A potential biomarker for EC
Published in The journal of obstetrics and gynaecology research (01-10-2020)“…Aim Elevated levels of 16α‐hydroxyestrone (16α‐OHE1) have been described in endometrial cancer (EC) and estrogen receptors (ER) expressed in endometrial…”
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3
Cytochrome P450-Mediated Estrogen Metabolites and Autoimmunity: Relationship and Link to Free Radicals
Published in Current drug metabolism (01-01-2016)“…Cytochrome P450 enzymes are responsible for the hydroxylation of various endogenous estrogens of the Phase I metabolic pathway. Cytochrome P450s produce…”
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4
Recombinant Interferon Alpha-2b is a High-Affinity Antigen for Type 1 Diabetes Autoantibodies
Published in Canadian journal of diabetes (01-04-2017)“…Abstract Objectives Type 1 diabetes results from T-cell-mediated destruction of the beta cells of the pancreas and is associated with several autoimmune…”
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5
Detection of 16α-Hydroxyestrone-histone 1 Adduct as High-Affinity Antigen for Rheumatoid Arthritis Autoantibodies
Published in Archivum Immunologiae et Therapiae Experimentalis (01-10-2018)“…Increased concentrations of 16α-hydroxyestrone (16α-OHE 1 ) have been observed in rheumatoid arthritis (RA), but the underlying mechanism of this remains…”
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6
The vicious cycle of chronic endometriosis and depression-an immunological and physiological perspective
Published in Frontiers in medicine (06-09-2024)“…Endometriosis is a chronic, estrogen-dependent, proinflammatory disease that can cause various dysfunctions. The main clinical manifestations of endometriosis…”
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Biologically Active α-Amino Amide Analogs and γδ T Cells-A Unique Anticancer Approach for Leukemia
Published in Frontiers in oncology (12-07-2021)“…Advanced stage cancers are aggressive and difficult to treat with mono-therapeutics, substantially decreasing patient survival rates. Hence, there is an urgent…”
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Cold Stress-induced Seed Germination and Biosynthesis of Polyphenolics Content in Medicinally Important Brassica rapa
Published in Phytomedicine Plus : International journal of phytotherapy and phytopharmacology (01-02-2022)“…:Brassica rapa is an annual to biennial herb, cultivated worldwide, and mostly adapted to temperate climates. It is commonly cultivated in many countries as…”
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Biochemical, biophysical, and thermodynamic analysis of in vitro glycated human serum albumin
Published in Biochemistry (Moscow) (01-02-2007)“…Glycated human serum albumin (HSA) is known to be involved in the pathogenesis of several diseases, and we have therefore investigated possible alterations in…”
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Antibodies against gluco-oxidatively modified human serum albumin detected in diabetes-associated complications
Published in International archives of allergy and immunology (01-01-2010)“…Glycated proteins present new immunological epitopes on their surface against which autoantibodies are generated that have a possible role in…”
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Effect of Storage on the Level of Aflatoxin M1 in Milk and Other Dairy Products Sold at Tripoli Province, Libya
Published in Journal of pure & applied microbiology : an international research journal of microbiology (01-12-2018)“…Milk and dairy products are one of the chief sources of nutrition for human beings particularly for infant and children. Aflatoxin M1 (AFM1 ) a hydroxylated…”
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16 α-Hydroxyestrone induced adduct generate high affinity autoantibodies in SLE
Published in Advances in medical sciences (01-03-2019)“…Increased 16 α-hydroxyestrone (16 α-OHE1) and autoantibodies against histone H1 (H1) have been well described in systemic lupus erythematosus (SLE), but the…”
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Increased binding of circulating systemic lupus erythematosus autoantibodies to recombinant interferon alpha 2b
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-12-2015)“…Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by various types of immunological abnormalities including circulating and…”
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Depression linked to higher antibodies production against estrogenized insulin in type 1 diabetes
Published in International immunopharmacology (01-09-2020)“…•Depression linked to higher antibodies production against estogenized insulin in T1D.•Depression enhance the release of IL-1β and IL-17 in T1D.•Depression…”
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15
Estrogenization of insulin by catecholestrogen produced high affinity autoantibodies and altered the normal function of insulin in type 1 diabetes
Published in Life sciences (1973) (01-09-2020)“…Insulin (Ins) covalently modified by catecholestrogens (CEs) was commonly found in diabetic patients who have developed insulin resistance. Estrogenization of…”
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Depression and its related parameters increased the production of autoantibodies against 16α-hydroxyestrone-albumin complex in systemic lupus erythematosus
Published in International immunopharmacology (01-06-2019)“…Depression is the common and early symptoms associated with early onset of SLE, 16α-hydroxyestrone (16α-OHE1) levels were found to be significantly higher in…”
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Depression enhanced the production of autoantibodies against 16α‑hydroxyestrone-estrogen receptor adduct in breast cancer
Published in International immunopharmacology (01-01-2019)“…Mentally depressed breast cancer (MDBC) patients expressed estrogen receptor (ER) and 16α‑hydroxyestrone (16α‑OHE1) is directly responsible for causing breast…”
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Pharmacological Activities of Zingiber officinale Roscoe: Inhibition of HSA Protein Glycation, Structure Stability and Function Restoration
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2024)“…Background: Controlled non-enzymatic glycation reactions are common under normal physiological conditions. However, during elevated blood glucose conditions,…”
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Preferential recognition of catechol-estrogen modified DNA by circulating autoantibodies in cancer patients
Published in Biochimie (01-02-2013)“…Catecholestrogens [4-hydroxyestradiol (4-OHE2)] have been implicated in human carcinogenesis, although the mechanism remains unestablished. In this study pUC…”
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Cancer Morbidity in Rheumatoid Arthritis: Role of Estrogen Metabolites
Published in BioMed research international (01-01-2013)“…Estrogen metabolites have been implicated in rheumatoid arthritis (RA) and cancer, although the mechanism remains unestablished. Some estrogen metabolites,…”
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