Search Results - "Khan, Themasap A."

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells by Sloan, Steven A., Darmanis, Spyros, Huber, Nina, Khan, Themasap A., Birey, Fikri, Caneda, Christine, Reimer, Richard, Quake, Stephen R., Barres, Ben A., Paşca, Sergiu P.

“…There is significant need to develop physiologically relevant models for investigating human astrocytes in health and disease. Here, we present an approach for…”
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Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model by Song, Ren, Pekrun, Katja, Khan, Themasap A., Zhang, Feijie, Paşca, Sergiu P., Kay, Mark A.

“…A limitation for recombinant adeno-associated virus (rAAV)-mediated gene transfer into the central nervous system (CNS) is the low penetration of vectors…”
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Neuronal defects in a human cellular model of 22q11.2 deletion syndrome by Khan, Themasap A., Revah, Omer, Gordon, Aaron, Yoon, Se-Jin, Krawisz, Anna K., Goold, Carleton, Sun, Yishan, Kim, Chul Hoon, Tian, Yuan, Li, Min-Yin, Schaepe, Julia M., Ikeda, Kazuya, Amin, Neal D., Sakai, Noriaki, Yazawa, Masayuki, Kushan, Leila, Nishino, Seiji, Porteus, Matthew H., Rapoport, Judith L., Bernstein, Jonathan A., O’Hara, Ruth, Bearden, Carrie E., Hallmayer, Joachim F., Huguenard, John R., Geschwind, Daniel H., Dolmetsch, Ricardo E., Paşca, Sergiu P.

“…22q11.2 deletion syndrome (22q11DS) is a highly penetrant and common genetic cause of neuropsychiatric disease. Here we generated induced pluripotent stem…”
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The Zika threat to the periphery by Khan, Themasap A., Paşca, Sergiu P.

“…Zika virus infection is associated with birth defects, including microcephaly, but also with disorders of peripheral nerves. Oh et al . use rodent and human…”
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