Search Results - "Khan, Naheed W"

Inhibiting autophagy reduces retinal degeneration caused by protein misfolding by Yao, Jingyu, Qiu, Yaoyan, Frontera, Eric, Jia, Lin, Khan, Naheed W., Klionsky, Daniel J., Ferguson, Thomas A., Thompson, Debra A., Zacks, David N.

“…Mutations in the genes necessary for the structure and function of vertebrate photoreceptor cells are associated with multiple forms of inherited retinal…”
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Prolonged Inner Retinal Photoreception Depends on the Visual Retinoid Cycle by Zhao, Xiwu, Pack, Weston, Khan, Naheed W, Wong, Kwoon Y

“…In addition to rods and cones, mammals have inner retinal photoreceptors called intrinsically photosensitive retinal ganglion cells (ipRGCs), which use the…”
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Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration by Yao, Jingyu, Jia, Lin, Feathers, Kecia, Lin, Chengmao, Khan, Naheed W., Klionsky, Daniel J., Ferguson, Thomas A., Zacks, David N.

“…Autophagy is a lysosomal degradation pathway critical to preventing the accumulation of cytotoxic proteins. Deletion of the essential autophagy gene Atg5 from…”
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Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15 by Thompson, Debra A, Khan, Naheed W, Othman, Mohammad I, Chang, Bo, Jia, Lin, Grahek, Garrett, Wu, Zhijian, Hiriyanna, Suja, Nellissery, Jacob, Li, Tiansen, Khanna, Hemant, Colosi, Peter, Swaroop, Anand, Heckenlively, John R

“…Animal models of human disease are an invaluable component of studies aimed at understanding disease pathogenesis and therapeutic possibilities. Mutations in…”
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Autoimmune retinopathy associated with monoclonal gammopathy of undetermined significance: a case report by Eton, Emily A, Abrams, Gary, Khan, Naheed W, Fahim, Abigail T

“…Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia and precursor to multiple myeloma. It has known ocular manifestations, but…”
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Contrast sensitivity deficits in patients with mutation-proven inherited retinal degenerations by Alahmadi, Badr O, Omari, Amro A, Abalem, Maria Fernanda, Andrews, Chris, Schlegel, Dana, Branham, Kari H, Khan, Naheed W, Fahim, Abigail, Jayasundera, Thiran

“…Patients with retinal diseases frequently complain of poor visual function even when visual acuity is relatively unaffected. This clinical finding has been…”
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A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration by CHAVALI, Venkata R. M, KHAN, Naheed W, CUKRAS, Catherine A, BARTSCH, Dirk-Uwe, JABLONSKI, Monica M, AYYAGARI, Radha

“…Late-onset retinal macular degeneration (L-ORD) is an autosomal dominant inherited disorder caused by a single missense mutation (S163R) in the CTRP5/C1QTNF5…”
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Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases by Parapuram, Sunil K, Cojocaru, Radu I, Chang, Jessica R, Khanna, Ritu, Brooks, Matthew, Othman, Mohammad, Zareparsi, Sepideh, Khan, Naheed W, Gotoh, Norimoto, Cogliati, Tiziana, Swaroop, Anand

“…Advanced age contributes to clinical manifestations of many retinopathies and represents a major risk factor for age-related macular degeneration, a leading…”
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Inherited Retinal Degeneration: Genetics, Disease Characterization, and Outcome Measures by Khan, Naheed W., Falsini, Benedetto, Kondo, Mineo, Robson, Anthony G.

“…With advances in genetic testing methodology, there is an increased detection of variants in multiple genes in the same family or even in the same individual,…”
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Macular hyperpigmentary changes in ABCA4 -Stargardt disease by Abalem, Maria Fernanda, Omari, Amro A, Schlegel, Dana, Khan, Naheed W, Jayasundera, Thiran

“…Stargardt disease (STGD) and age-related macular degeneration (AMD) share clinical and pathophysiological features. In AMD, macular hyperpigmentary changes are…”
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Rapid visual field constriction in a patient with retinitis pigmentosa and pituitary adenoma by Al-Hasani, Hayder, Khan, Naheed W., Branham, Kari H., Heckenlively, John R., Sullivan, Stephen E., De Lott, Lindsey B., Fahim, Abigail T.

“…To report a case of pituitary adenoma in a patient with retinitis pigmentosa (RP) and consequent rapid constriction of the visual field in each eye, which is…”
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Acute panretinal structural and functional abnormalities after intravitreous ocriplasmin injection by Fahim, Abigail T, Khan, Naheed W, Johnson, Mark W

“…IMPORTANCE Ocriplasmin cleaves fibronectin and laminin, components of the vitreous gel, and is used as a pharmacologic treatment for vitreomacular traction…”
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Establishing baseline rod electroretinogram values in achromatopsia and cone dystrophy by Wang, Isaac, Khan, Naheed W., Branham, Kari, Wissinger, B., Kohl, Susanne, Heckenlively, J. R.

“…Purpose To establish the normal range of values for rod-isolated b-wave amplitudes in achromatopsia and cone dystrophies. Methods We reviewed charts of 112…”
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Adherence and satisfaction in Argus II prosthesis users: a self determination theory model by Khan, Mariam, Branham, Kari, Jayasundera, Kanishka T, Khan, Naheed W

“…Self-determination theory (SDT) of human motivation was used to examine associations between different forms of motivation in Argus II retinal prosthesis users…”
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Gene Supplementation in Mice Heterozygous for the D477G RPE65 Variant Implicated in Autosomal Dominant Retinitis Pigmentosa by Feathers, Kecia L, Jia, Lin, Khan, Naheed W, Smith, Alexander J, Ma, Jian-Xing, Ali, Robin R, Thompson, Debra A

“…The use of vectors for gene supplementation has achieved spectacular success as a treatment for individuals with autosomal recessive retinal disease caused by…”
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Multifocal visual evoked potentials for early glaucoma detection by Weizer, Jennifer S, Musch, David C, Niziol, Leslie M, Khan, Naheed W

“…To compare multifocal visual evoked potentials (mfVEP) with other detection methods in early open-angle glaucoma. Ten patients with suspected glaucoma and 5…”
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Detailed clinical characterisation, unique features and natural history of autosomal recessive RDH12 -associated retinal degeneration by Fahim, Abigail T, Bouzia, Zaina, Branham, Kari H, Kumaran, Neruban, Vargas, Mauricio E, Feathers, Kecia L, Perera, N Dayanthi, Young, Kelly, Khan, Naheed W, Heckenlively, John R, Webster, Andrew R, Pennesi, Mark E, Ali, Robin R, Thompson, Debra A, Michaelides, Michel

“…Defects in retinol dehydrogenase 12 ( ) account for 3.4%-10.5 % of Leber congenital amaurosis and early-onset severe retinal dystrophy (EOSRD) and are a…”
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ISCEV extended protocol for the photopic On–Off ERG by Sustar, Maja, Holder, Graham E., Kremers, Jan, Barnes, Claire S., Lei, Bo, Khan, Naheed W., Robson, Anthony G.

“…The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum procedure, but…”
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Analysis of photoreceptor function and inner retinal activity in juvenile X-linked retinoschisis by Khan, Naheed W, Jamison, Jeffrey A, Kemp, Jennifer A, Sieving, Paul A

“…Thirteen retinoschisis males with genotyped XLRS1 gene mutations were examined by electroretinogram (ERG) techniques to determine photoreceptor involvement and…”
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Development of a Gene Therapy Vector for RDH12 -Associated Retinal Dystrophy by Feathers, Kecia L, Jia, Lin, Perera, Nirosha Dayanthi, Chen, Adrienne, Presswalla, Feriel K, Khan, Naheed W, Fahim, Abigail T, Smith, Alexander J, Ali, Robin R, Thompson, Debra A

“…Early-onset severe retinal dystrophy (EOSRD) is a genetically heterogeneous group of diseases resulting in serious visual disability in children. A significant…”
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