Search Results - "Khan, Naeem D"
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Difference in Medication Adherence Between Patients Prescribed a 30-Day Versus 90-Day Supply After Acute Myocardial Infarction
Published in Journal of the American Heart Association (05-01-2021)“…Background Evidence-based medication adherence rates after a myocardial infarction are low. We hypothesized that 90-day prescriptions are underused and may…”
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Impact of Diabetes Mellitus on the Pharmacodynamic Effects of Ticagrelor Versus Clopidogrel in Troponin-Negative Acute Coronary Syndrome Patients Undergoing Ad Hoc Percutaneous Coronary Intervention
Published in Journal of the American Heart Association (01-04-2017)“…Diabetes mellitus (DM) is associated with enhanced platelet reactivity and impaired response to oral antiplatelet therapy, including clopidogrel. This post hoc…”
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Effect of Medication Co-payment Vouchers on P2Y12 Inhibitor Use and Major Adverse Cardiovascular Events Among Patients With Myocardial Infarction: The ARTEMIS Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (01-01-2019)“…IMPORTANCE: Despite guideline recommendations, many patients discontinue P2Y12 inhibitor therapy earlier than the recommended 1 year after myocardial…”
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New Heart Failure After Myocardial Infarction (From the National Cardiovascular Data Registries [NCDR] Linked With All-Payer Claims)
Published in The American journal of cardiology (15-07-2021)“…•After MI, 18.8% of patients develop new HF within 5 years after discharge.•CKD and recurrent MI are the strongest risk factors for new HF after MI.•A simple…”
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Pharmacokinetics and pharmacodynamics of ticagrelor in subjects on hemodialysis and subjects with normal renal function
Published in European journal of clinical pharmacology (01-09-2018)“…Purpose This single-dose, randomized, open-label, parallel-group, and crossover study assessed pharmacokinetics (PK), pharmacodynamics (PD), and safety of…”
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Translating clinical evidence into value-based payment models: pooled analyses of innovative real-world outcomes agreements for ticagrelor in the United States
Published in The American journal of managed care (01-10-2020)“…Innovative value strategies for reimbursement of medications include value-based agreements (VBAs) between payers and pharmaceutical manufacturers, which have…”
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Hospitalization for Myocardial Infarction with Ticagrelor or Clopidogrel in Patients with Acute Coronary Syndrome: An On-Treatment Comparative Effectiveness Analysis
Published in Cardiology and therapy (01-12-2021)“…Introduction Prescribing patterns and suboptimal adherence present methodological challenges for real-world head-to-head comparisons of ticagrelor and…”
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Contemporary Predictors of Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention: A Nationally Representative US Sample
Published in Journal of clinical medicine (11-05-2024)“…: Patient outcomes after percutaneous coronary intervention (PCI) have improved over the last 30 years due to better techniques, therapies, and care processes…”
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Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD 2 score
Published in Stroke and vascular neurology (01-06-2021)“…Long-term outcomes for Medicare beneficiaries hospitalised with transient ischaemic attack (TIA) and role of ABCD score in identifying high-risk individuals…”
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Ticagrelor in Peripheral Artery Disease Endovascular Revascularization (TI-PAD): Challenges in clinical trial execution
Published in Vascular medicine (London, England) (01-12-2018)“…There is limited evidence to guide clinical decision-making for antiplatelet therapy in peripheral artery disease (PAD) in the setting of lower extremity…”
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Addressing Therapeutic Inertia in 2020 and Beyond: A 3-Year Initiative of the American Diabetes Association
Published in Clinical diabetes (01-10-2020)“…Research has shown that getting to glycemic targets early on leads to better outcomes in people with type 2 diabetes; yet, there has been no improvement in the…”
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Agreement and Accuracy of Medication Persistence Identified by Patient Self-report vs Pharmacy Fill: A Secondary Analysis of the Cluster Randomized ARTEMIS Trial
Published in JAMA cardiology (01-05-2020)“…Pharmacy fill data are increasingly accessible to clinicians and researchers to evaluate longitudinal medication persistence beyond patient self-report. To…”
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Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD2 score
Published in Stroke and vascular neurology (01-06-2021)“…BackgroundLong-term outcomes for Medicare beneficiaries hospitalised with transient ischaemic attack (TIA) and role of ABCD2 score in identifying high-risk…”
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Association of a P2Y12 Inhibitor Copayment Reduction Intervention With Persistence and Adherence With Other Secondary Prevention Medications: A Post Hoc Analysis of the ARTEMIS Cluster-Randomized Clinical Trial
Published in JAMA cardiology (01-01-2020)“…The Affordability and Real-World Antiplatelet Treatment Effectiveness After Myocardial Infarction Study (ARTEMIS) cluster-randomized trial found that copayment…”
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Clinically feasible stratification of 1-year to 3-year post-myocardial infarction risk
Published in Open heart (2018)“…ObjectivePost-myocardial infarction (MI) care is crucial to preventing recurrent major adverse cardiovascular events (MACE), but can be complicated to…”
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Effect of Medication Co-payment Vouchers on P2Y^sub 12^ Inhibitor Use and Major Adverse Cardiovascular Events Among Patients With Myocardial Infarction: The ARTEMIS Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (01-01-2019)“…Importance Despite guideline recommendations, many patients discontinue P2Y12 inhibitor therapy earlier than the recommended 1 year after myocardial infarction…”
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Abstract 14907: Clinically Feasible Electronic Health Record Tool for Stratification of 1- to 3-Year Post-Myocardial Infarction Risk of Cardiovascular Events: The Intermountain Acute Coronary Syndromes Risk Scores
Published in Circulation (New York, N.Y.) (10-11-2015)“…BackgroundRandomized trials report that prolonged (>1 year) use of P2Y12 inhibitors with aspirin after myocardial infarction (MI) reduces stent thrombosis and…”
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Abstract 12443: Incident Heart Failure Risk After Acute Myocardial Infarction is Stratified by the Intermountain Major Adverse Cardiovascular Events (IMACE) Risk Scores
Published in Circulation (New York, N.Y.) (11-11-2016)“…IntroductionPreviously, the Intermountain Mortality Risk Scores (IMRS) were created to predict all-cause mortality, but also predicted incident heart failure…”
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Abstract 12079: Initial Report From an Emergency-Department-Based Registry of NSTEMI Patients Given Upstream Advanced Oral Antiplatelet Therapy
Published in Circulation (New York, N.Y.) (11-11-2016)“…IntroductionThere are scant data on use of P2Y12 antagonist therapy upstream of diagnostic angiography (DA), especially when administered in the emergency…”
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