Thrombotic Microangiopathic Syndrome as Presenting Manifestation of HIV

Thrombotic Microangiopathic Syndrome as Presenting Manifestation of HIV

Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) is a rare but well-described complication of advanced human immunodeficiency virus (HIV) infection. However, TTP-HUS had been rarely described as the presenting manifestation of HIV infection. We describe a case of a 45-year-old...

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Bibliographic Details
Published in:Infectious diseases in clinical practice (Baltimore, Md.) Vol. 13; no. 4; pp. 208 - 210
Main Authors: Aslam, Ahmed Faraz, Aslam, Ahmad Kamal, Khan, Mutahir Ubaid, DiPillo, Frank
Format: Journal Article
Language:English
Published: Lippincott Williams & Wilkins, Inc 01-07-2005
Online Access:Get full text
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Summary:Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) is a rare but well-described complication of advanced human immunodeficiency virus (HIV) infection. However, TTP-HUS had been rarely described as the presenting manifestation of HIV infection. We describe a case of a 45-year-old female who presented with classic manifestations of TTP-HUS and was subsequently found to have HIV. Patient responded to conventional treatment with plasma exchange. We conclude that clinicians need to have a high index of suspicion for retroviral infection when evaluating patients with TTP-HUS even when risk behaviors are not readily apparent.
ISSN:1056-9103
1536-9943
DOI:10.1097/01.idc.0000168468.56438.a0