Search Results - "Khan, Mohd. Wajid Ali"
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Cytochrome P450-Mediated Estrogen Metabolites and Autoimmunity: Relationship and Link to Free Radicals
Published in Current drug metabolism (01-01-2016)“…Cytochrome P450 enzymes are responsible for the hydroxylation of various endogenous estrogens of the Phase I metabolic pathway. Cytochrome P450s produce…”
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CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer
Published in Molecular cancer (24-03-2022)“…Cancer is caused by a combination of genetic and epigenetic abnormalities. Current cancer therapies are limited due to the complexity of their mechanism,…”
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Estrogenization of insulin by catecholestrogen produced high affinity autoantibodies and altered the normal function of insulin in type 1 diabetes
Published in Life sciences (1973) (01-09-2020)“…Insulin (Ins) covalently modified by catecholestrogens (CEs) was commonly found in diabetic patients who have developed insulin resistance. Estrogenization of…”
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Biochemical, biophysical, and thermodynamic analysis of in vitro glycated human serum albumin
Published in Biochemistry (Moscow) (01-02-2007)“…Glycated human serum albumin (HSA) is known to be involved in the pathogenesis of several diseases, and we have therefore investigated possible alterations in…”
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Antibodies against gluco-oxidatively modified human serum albumin detected in diabetes-associated complications
Published in International archives of allergy and immunology (01-01-2010)“…Glycated proteins present new immunological epitopes on their surface against which autoantibodies are generated that have a possible role in…”
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Endometrial cancer patients have high affinity antibodies for estrogen metabolite–receptor aggregate: A potential biomarker for EC
Published in The journal of obstetrics and gynaecology research (01-10-2020)“…Aim Elevated levels of 16α‐hydroxyestrone (16α‐OHE1) have been described in endometrial cancer (EC) and estrogen receptors (ER) expressed in endometrial…”
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Emerging Nanomaterials Biosensors in Breathalyzers for Detection of COVID-19: Future Prospects
Published in Inorganics (01-12-2023)“…In recent times, the global landscape of disease detection and monitoring has been profoundly influenced by the convergence of nanotechnology and biosensing…”
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Gas Sensing Performance of Zinc Oxide Nanoparticles Fabricated via Ochradenus baccatus Leaf
Published in Chemosensors (01-02-2024)“…ZnO nanoparticles (NPs) were prepared by green synthesis using plant leaf extraction of Ochradenus baccatus and characterized by XRD, FESEM, HRTEM, and Raman…”
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Effect of Storage on the Level of Aflatoxin M1 in Milk and Other Dairy Products Sold at Tripoli Province, Libya
Published in Journal of pure & applied microbiology : an international research journal of microbiology (01-12-2018)“…Milk and dairy products are one of the chief sources of nutrition for human beings particularly for infant and children. Aflatoxin M1 (AFM1 ) a hydroxylated…”
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Catecholoestrogens: possible role in systemic lupus erythematosus
Published in Rheumatology (Oxford, England) (01-11-2009)“…It is well established that risk of developing SLE is higher among women compared with men but only very little is understood about the underlying mechanisms…”
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Depression linked to higher antibodies production against estrogenized insulin in type 1 diabetes
Published in International immunopharmacology (01-09-2020)“…•Depression linked to higher antibodies production against estogenized insulin in T1D.•Depression enhance the release of IL-1β and IL-17 in T1D.•Depression…”
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Editorial: Immunotherapy and small molecule inhibitors as combinational cancer therapeutics
Published in Frontiers in immunology (22-08-2023)Get full text
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Depression and its related parameters increased the production of autoantibodies against 16α-hydroxyestrone-albumin complex in systemic lupus erythematosus
Published in International immunopharmacology (01-06-2019)“…Depression is the common and early symptoms associated with early onset of SLE, 16α-hydroxyestrone (16α-OHE1) levels were found to be significantly higher in…”
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Depression enhanced the production of autoantibodies against 16α‑hydroxyestrone-estrogen receptor adduct in breast cancer
Published in International immunopharmacology (01-01-2019)“…Mentally depressed breast cancer (MDBC) patients expressed estrogen receptor (ER) and 16α‑hydroxyestrone (16α‑OHE1) is directly responsible for causing breast…”
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Cytokine Response in SARS-CoV-2 Infection in the Elderly
Published in Journal of inflammation research (01-01-2020)“…The last few months of 2019 witnessed the emergence, rise and rapid spread of a novel coronavirus known as severe acute respiratory syndrome coronavirus-2…”
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Glycation end-products specific auto-antibodies in Systemic Lupus Erythematosus
Published in Bioinformation (31-03-2022)“…Systemic lupus erythematosus (SLE) is an autoimmune disease, which is highly inflammatory. Compared to a healthy control group, SLE patients exhibit a higher…”
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Directional preference for glioblastoma cancer cell membrane encapsulated nanoparticle population: A probabilistic approach for cancer therapeutics
Published in Frontiers in immunology (29-03-2023)“…Selective cancer cell recognition is the most challenging objective in the targeted delivery of anti-cancer agents. Extruded specific cancer cell membrane…”
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Increased Levels of Autoantibodies against ROS-Modified Proteins in Depressed Individuals with Decrease in Antibodies against SARS-CoV-2 Antigen (S1-RBD)
Published in Current issues in molecular biology (28-10-2022)“…Coronavirus 2019 (COVID-19) disease management is highly dependent on the immune status of the infected individual. An increase in the incidence of depression…”
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Presence of Circulatory Autoantibodies Against ROS-Modified Histone H1 Protein in Lymphoma Patients
Published in Frontiers in genetics (25-05-2022)“…Lymphoma is a chronic inflammatory disease in which the immune system is highly affected. Increased oxidative stress is one of the common conditions of cancer…”
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