Search Results - "Khan, Mohammad A. H."

Immunisation with a plasmid DNA vaccine encoding gonadotrophin releasing hormone (GnRH-I) and T-helper epitopes in saline suppresses rodent fertility by Khan, Mohammad A.H, Ogita, Kazuhide, Ferro, Valerie A, Kumasawa, Keiichi, Tsutsui, Tateki, Kimura, Tadashi

“…Summary Research into active immunisation against gonadotrophin releasing hormone (GnRH-I) has gained widespread acceptance as a means of controlling…”
Get full text

Effect of immunisation against gonadotrophin releasing hormone isoforms (mammalian GnRH-I, chicken GnRH-II and lamprey GnRH-III) on murine spermatogenesis by Khan, Mohammad A.H, Prevost, Martine, Waterston, Mary M, Harvey, Michael J.A, Ferro, Valerie A

“…Abstract In mammals, the hypothalamic decapeptide, gonadotrophin releasing hormone (GnRH-I), is regarded as the major fertility regulating peptide. However, a…”
Get full text

Immunisation of male mice with a plasmid DNA vaccine encoding gonadotrophin releasing hormone (GnRH-I) and T-helper epitopes suppresses fertility in vivo by Khan, Mohammad A.H, Ferro, Valerie A, Koyama, Shinsuke, Kinugasa, Yukiko, Song, Mihyon, Ogita, Kazuhide, Tsutsui, Tateki, Murata, Yuji, Kimura, Tadashi

“…Abstract Immunisation against mammalian gonadotrophin releasing hormone (GnRH-I) linked to large carrier proteins has been shown to disrupt fertility. However,…”
Get full text

Rationalising drug delivery using nanoparticles: a combined simulation and immunology study of GnRH adsorbed to silica nanoparticles by Connell, David J., Gebril, Ayman, Khan, Mohammad A. H., Patwardhan, Siddharth V., Kubiak-Ossowska, Karina, Ferro, Valerie A., Mulheran, Paul A.

“…Silica nanoparticles (SiNPs) have been shown to have significant potential for drug delivery and as adjuvants for vaccines. We have simulated the adsorption of…”
Get full text

Use of a Highly Specific Monoclonal Antibody Against the Central Variable Amino Acid Sequence of Mammalian Gonadotropin Releasing Hormone to Evaluate GnRH-I Tissue Distribution Compared With GnRH-I Binding Sites in Adult Male Rats by Khan, Mohammad A. H., Ferro, Valerie A., Stimson, William H.

“…PROBLEM:  Recent evidence shows the existence of numerous isoforms of gonadotropin releasing hormone (GnRH), with high sequence homology and a core variable…”
Get full text

Influence of Carrier Protein Conjugation Site and Terminal Modification of a GnRH-I Peptide Sequence in the Development of a Highly Specific Anti-fertility Vaccine. Part I by Ferro, Valerie A., Khan, Mohammad A. H., Earl, Elizabeth R., Harvey, Michael J. A., Colston, Angela, Stimson, William H.

“…PROBLEM: We previously immunoneutralized gonadotrophin releasing hormone (GnRH), using an analogue of GnRH (des‐1 GnRH‐I), conjugated to tetanus toxoid via a…”
Get full text

Plasmid DNA vaccine coding eight repeats of gonadotrophin-releasing hormone induced atrophy of prostate in male mice by Rima, Umme K., Bari, Abu S.M., Hossain, Mohammad Z., Khan, Mohammad A.H.

“…Prostate hyperplasia and neoplasia are major illness of men and elderly dogs. Treatment of prostate cancer requires androgen deprivation surgery or therapy to…”
Get full text

Immunisation of male mice with a plasmid DNA vaccine encoding gonadotrophin releasing hormone (GnRH-I) and T-helper epitopes suppresses fertilityin vivo by Khan, Mohammad AH, Ferro, Valerie A, Koyama, Shinsuke, Kinugasa, Yukiko, Song, Mihyon, Ogita, Kazuhide, Tsutsui, Tateki, Murata, Yuji, Kimura, Tadashi

“…Immunisation against mammalian gonadotrophin releasing hormone (GnRH-I) linked to large carrier proteins has been shown to disrupt fertility. However, various…”
Get full text

Immunoneutralisation of GnRH-I, without cross-reactivity to GnRH-II, in the development of a highly specific anti-fertility vaccine for clinical and veterinary uses by FERRO, Valerie A, KHAN, Mohammad A. H, LATIMER, Valerie S, BROWN, Donald, URBANSKI, Henryk F, STIMSON, William H

Get full text