Search Results - "Khan, Michael Z."
-
1
A novel task of canine olfaction for use in adult and senior pet dogs
Published in Scientific reports (08-02-2023)“…While much work has been done in the field of canine olfaction, there has been little exploration of hyposmia or anosmia. This is partly due to difficulties in…”
Get full text
Journal Article -
2
Relationship between hearing, cognitive function, and quality of life in aging companion dogs
Published in Journal of veterinary internal medicine (01-09-2022)“…Background Elderly people with presbycusis are at higher risk for dementia and depression than the general population. There is no information regarding…”
Get full text
Journal Article -
3
P7C3 Neuroprotective Chemicals Block Axonal Degeneration and Preserve Function after Traumatic Brain Injury
Published in Cell reports (Cambridge) (25-09-2014)“…The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3…”
Get full text
Journal Article -
4
Behavioral disturbances in estrogen-related receptor alpha-null mice
Published in Cell reports (Cambridge) (21-04-2015)“…Eating disorders, such as anorexia nervosa and bulimia nervosa, are common and severe mental illnesses of unknown etiology. Recently, we identified a rare…”
Get full text
Journal Article -
5
Relationship between engagement with the impossible task, cognitive testing, and cognitive questionnaires in a population of aging dogs
Published in Frontiers in veterinary science (04-01-2023)“…The aim of this study was to evaluate the engagement of aging dogs with a cognitively challenging and potentially frustrating task (the impossible task). Based…”
Get full text
Journal Article -
6
(−)-P7C3-S243 Protects a Rat Model of Alzheimer’s Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia
Published in Biological psychiatry (1969) (01-10-2018)“…In addition to cognitive deficits, Alzheimer’s disease (AD) is associated with other neuropsychiatric symptoms, including severe depression. Indeed, depression…”
Get full text
Journal Article -
7
Use of Cognitive Testing, Questionnaires, and Plasma Biomarkers to Quantify Cognitive Impairment in an Aging Pet Dog Population
Published in Journal of Alzheimer's disease (2022)“…Aging dogs may suffer from canine cognitive dysfunction syndrome (CCDS), a condition in which cognitive decline is associated with amyloid pathology and…”
Get more information
Journal Article -
8
Collateralizing ventral subiculum melanocortin 4 receptor circuits regulate energy balance and food motivation
Published in Physiology & behavior (01-04-2023)“…•NAc-projecting vSUBMC4R+ neurons send collateral projections to hypothalamic nuclei.•Activation of NAc-projecting vSUBMC4R+neurons affect appetitive…”
Get full text
Journal Article -
9
The Eating-Disorder Associated HDAC4 A778T Mutation Alters Feeding Behaviors in Female Mice
Published in Biological psychiatry (1969) (01-05-2017)“…While eating disorders (EDs) are thought to result from a combination of environmental and psychological stressors superimposed on genetic vulnerability, the…”
Get full text
Journal Article -
10
The Eating-Disorder Associated HDAC4A778T Mutation Alters Feeding Behaviors in Female Mice
Published in Biological psychiatry (1969) (01-05-2017)“…Abstract Background While eating disorders (EDs) are thought to result from a combination of environmental and psychological stressors superimposed on genetic…”
Get full text
Journal Article -
11
Loss of estrogen-related receptor alpha disrupts ventral-striatal synaptic function in female mice
Published in Neuroscience (04-08-2016)“…Highlights • Loss of Esrra increases basal excitatory synaptic transmission in the ventral striatum specifically in female mice. • Loss of Esrra decreases…”
Get full text
Journal Article