Search Results - "Khan, Mansoor"

A new chapter in pharmaceutical manufacturing: 3D-printed drug products by Norman, James, Madurawe, Rapti D., Moore, Christine M.V., Khan, Mansoor A., Khairuzzaman, Akm

“…FDA recently approved a 3D-printed drug product in August 2015, which is indicative of a new chapter for pharmaceutical manufacturing. This review article…”
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3D-printing of lopinavir printlets by selective laser sintering and quantification of crystalline fraction by XRPD-chemometric models by Hamed, Rania, Mohamed, Eman M., Rahman, Ziyaur, Khan, Mansoor A.

“…[Display omitted] The objectives of this study were to develop and characterize amorphous lopinavir (LPV) printlets and to the quantify crystalline fraction of…”
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Comprehensive Total Cost of Ownership Framework for Alternative Fuel Public Transportation Buses by Khan, Mansoor J. A., Onat, Nuri Cihat

“…Sustainable fleet management seeks to deliver the best service with a standard of service defined by state regulatory bodies by utilizing and managing large…”
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A meta-analysis of the efficacy of whole-body computed tomography imaging in the management of trauma and injury by Chidambaram, Swathikan, Goh, En Lin, Khan, Mansoor A

“…Abstract Background Traumatic injury is the third leading cause of death overall. To optimize the outcomes in these patients, hospitals employ whole-body…”
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Understanding Pharmaceutical Quality by Design by Yu, Lawrence X., Amidon, Gregory, Khan, Mansoor A., Hoag, Stephen W., Polli, James, Raju, G. K., Woodcock, Janet

“…This review further clarifies the concept of pharmaceutical quality by design (QbD) and describes its objectives. QbD elements include the following: (1) a…”
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Data integrity issues in pharmaceutical industry: Common observations, challenges and mitigations strategies by Charoo, Naseem A., Khan, Mansoor A., Rahman, Ziyaur

“…[Display omitted] Data integrity (DI) reaffirms the pharmaceutical industry's commitment to manufacture drugs that are safe, effective and fulfil quality…”
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Selective laser sintering 3D printing - an overview of the technology and pharmaceutical applications by Charoo, Naseem A., Barakh Ali, Sogra F., Mohamed, Eman M., Kuttolamadom, Mathew A., Ozkan, Tanil, Khan, Mansoor A., Rahman, Ziyaur

“…Food and Drug Administration (FDA) has approved a drug product (Spritam®) and many medical devices manufactured by three-dimensional printing (3DP) processes…”
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Understanding the effects of formulation and process variables on the printlets quality manufactured by selective laser sintering 3D printing by Barakh Ali, Sogra F., Mohamed, Eman M., Ozkan, Tanil, Kuttolamadom, Mathew A., Khan, Mansoor A., Asadi, Amir, Rahman, Ziyaur

“…[Display omitted] The focus of the study was to understand the effects of formulation and process variables on the printlets quality manufactured by selective…”
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Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma by Cannon, Jeremy W, Khan, Mansoor A, Raja, Ali S, Cohen, Mitchell J, Como, John J, Cotton, Bryan A, Dubose, Joseph J, Fox, Erin E, Inaba, Kenji, Rodriguez, Carlos J, Holcomb, John B, Duchesne, Juan C

“…The resuscitation of severely injured bleeding patients has evolved into a multi-modal strategy termed damage control resuscitation (DCR). This guideline…”
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HIV-1 Tat and cocaine impact astrocytic energy reservoir influence on miRNA epigenetic regulation by Doke, Mayur, Kashanchi, Fatah, Khan, Mansoor A., Samikkannu, Thangavel

“…Astrocytes are the primary regulator of energy metabolism in the central nervous system (CNS), and impairment of astrocyte's energy resource may trigger…”
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Influence of psychostimulants and opioids on epigenetic modification of class III histone deacetylase (HDAC)-sirtuins in glial cells by Sivalingam, Kalaiselvi, Doke, Mayur, Khan, Mansoor A., Samikkannu, Thangavel

“…Substance abuse affects the central nervous system (CNS) and remains a global health problem. Psychostimulants, such as cocaine and methamphetamine (METH), and…”
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Nitroso Impurities in Drug Products: An Overview of Risk Assessment, Regulatory Milieu, and Control Strategy by Charoo, Naseem A., Dharani, Sathish, Khan, Mansoor A., Rahman, Ziyaur

“…Many nitrosamines have been recognized to be carcinogenic for many decades. Despite the fact that several nitrosamine precursors are frequently used in the…”
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Non-destructive methods of characterization of risperidone solid lipid nanoparticles by Rahman, Ziyaur, Zidan, Ahmed S., Khan, Mansoor A.

“…We developed and optimized solid lipid nanoparticle (SLN) formulation of risperidone using compritol 888 ATO as a matrix by design of experiment strategy. The…”
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A New Hybrid Approach to Forecast Wind Power for Large Scale Wind Turbine Data Using Deep Learning with TensorFlow Framework and Principal Component Analysis by Khan, Mansoor, Liu, Tianqi, Ullah, Farhan

“…Wind power forecasting plays a vital role in renewable energy production. Accurately forecasting wind energy is a significant challenge due to the uncertain…”
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Patient In-Use Stability Testing of FDA-Approved Metformin Combination Products for N-Nitrosamine Impurity by Dharani, Sathish, Mohamed, Eman M., Rahman, Ziyaur, Khan, Mansoor A.

“…Between February 2020 and January 2022, the Food and Drug Administration (FDA) recalled 281 metformin extended-release products due to the presence of N…”
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Development of stable amorphous solid dispersion and quantification of crystalline fraction of lopinavir by spectroscopic-chemometric methods by Hamed, Rania, Mohamed, Eman M., Sediri, Khaldia, Khan, Mansoor A., Rahman, Ziyaur

“…[Display omitted] This study aimed to improve the dissolution of the poorly soluble drug lopinavir (LPV) by preparing amorphous solid dispersions (ASDs) using…”
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Effect of patients in-use and accelerated stability conditions on quality attributes and pharmacokinetic profile of four FDA approved extended-release anti-epileptic-drug products by Mohamed, Eman M., Hassan, Mariame A., Sibhat, Gereziher, Khuroo, Tahir, Rahman, Ziyaur, Khan, Mansoor A.

“…[Display omitted] Divalproex (DVS) is a popular drug widely used in various neurological and psychiatric disorders. Commercially, it is a multisource-drug…”
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A quality by design (QbD) case study on liposomes containing hydrophilic API: II. Screening of critical variables, and establishment of design space at laboratory scale by Xu, Xiaoming, Khan, Mansoor A., Burgess, Diane J.

“…Contour plot for EE% with respect to lipid concentration and drug concentration. Red star points are central composite design points. Within the circle (red…”
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Predicting hydrophilic drug encapsulation inside unilamellar liposomes by Xu, Xiaoming, Khan, Mansoor A., Burgess, Diane J.

“…Mathematical model (bottom) and schematic drawing of a unilamellar vesicle (right) and vesicles of various sizes distributed in sample medium (left). d,…”
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Comparative Evaluation of Flow for Pharmaceutical Powders and Granules by Shah, Rakhi B., Tawakkul, Mobin A., Khan, Mansoor A.

“…The objective of the present work was to carry out a systematic evaluation of flow of pharmaceutical powders and granules using compendial and non-compendial…”
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