Search Results - "Khan, Lillian"
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Miniaturization and optimization of 384-well compatible RNA sequencing library preparation
Published in PloS one (10-01-2019)“…Preparation of high-quality sequencing libraries is a costly and time-consuming component of metagenomic next generation sequencing (mNGS). While the overall…”
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A novel cause of chronic viral meningoencephalitis: Cache Valley virus
Published in Annals of neurology (01-07-2017)“…Objective Immunodeficient patients are particularly vulnerable to neuroinvasive infections that can be challenging to diagnose. Metagenomic next generation…”
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Kelch-like Protein 11 Antibodies in Seminoma-Associated Paraneoplastic Encephalitis
Published in The New England journal of medicine (04-07-2019)“…Brain-stem and cerebellar encephalitis without the conventional anti-Ma2 autoantibody developed in a man with a history of seminoma. Phage display was used to…”
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Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing
Published in JAMA neurology (01-08-2018)“…Identifying infectious causes of subacute or chronic meningitis can be challenging. Enhanced, unbiased diagnostic approaches are needed. To present a case…”
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Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens
Published in Genome medicine (25-08-2016)“…Ocular infections remain a major cause of blindness and morbidity worldwide. While prognosis is dependent on the timing and accuracy of diagnosis, the etiology…”
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Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens
Published in mBio (17-12-2019)“…The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of…”
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ZSCAN1 Autoantibodies Are Associated with Pediatric Paraneoplastic ROHHAD
Published in Annals of neurology (01-08-2022)“…Objective Rapid‐onset Obesity with Hypothalamic Dysfunction, Hypoventilation and Autonomic Dysregulation (ROHHAD), is a severe pediatric disorder of uncertain…”
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Clinicopathology conference: 41‐year‐old woman with chronic relapsing meningitis
Published in Annals of neurology (01-02-2019)Get full text
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Central Nervous System Virus Infection in African Children with Cerebral Malaria
Published in The American journal of tropical medicine and hygiene (01-07-2020)“…We aimed to identify the contribution of central nervous system (CNS) viral coinfection to illness in African children with retinopathy-negative or…”
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Author Correction: Pan-viral serology implicates enteroviruses in acute flaccid myelitis
Published in Nature medicine (01-10-2021)Get full text
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Genomic and serologic characterization of enterovirus A71 brainstem encephalitis
Published in Neurology : neuroimmunology & neuroinflammation (01-05-2020)“…In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the…”
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Erratum to: Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens
Published in Genome medicine (22-11-2016)“…It has come to our attention that there is an error in Fig. 3a for this article [1]. The correct version of Fig. 3a can be found below. The red markers now…”
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Real world comparison of PENFAST and UK Penicillin allergy clinical decision rules in an Adult Allergy service in the UK
Published in Journal of allergy and clinical immunology (01-02-2024)Get full text
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Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2018)“…Lower respiratory tract infections (LRTIs) lead to more deaths each year than any other infectious disease category. Despite this, etiologic LRTI pathogens are…”
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Pan-viral serology implicates enteroviruses in acute flaccid myelitis
Published in Nature medicine (01-11-2019)“…Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM) 1 – 6 . Epidemiologic evidence suggests…”
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Pediatric Brainstem Encephalitis Outbreak Investigation with Metagenomic Next-Generation Sequencing (CCI.002)
Published in Neurology (10-04-2018)“…Abstract only…”
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Illuminating Tuberculosis Meningitis with Metagenomics and FLASH Enrichment (S45.005)
Published in Neurology (09-04-2019)“…Abstract only…”
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A novel cause of chronic viral meningoencephalitis: C ache Valley virus
Published in Annals of neurology (01-07-2017)“…Objective Immunodeficient patients are particularly vulnerable to neuroinvasive infections that can be challenging to diagnose. Metagenomic next generation…”
Get full text
Journal Article