Search Results - "Khan, Jalaluddin Azam"

Scale-up fermentation of Escherichia coli for the production of recombinant endoglucanase from Clostridium thermocellum by Shahzadi, Iram, Al-Ghamdi, Maryam A., Nadeem, Muhammad Shahid, Sajjad, Muhammad, Ali, Asif, Khan, Jalaluddin Azam, Kazmi, Imran

“…Endoglucanase (EC 3.2.1.4) catalysing the hydrolysis of β-1.4-glycosidic linkage of cellulose molecules is an enzyme of tremendous industrial importance. The…”
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Design, Synthesis, and Bioevaluation of Indole Core Containing 2‑Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A/B for the Treatment of Alzheimer Disease by Shahid Nadeem, Muhammad, Azam Khan, Jalaluddin, Kazmi, Imran, Rashid, Umer

“…In continuation of our previous study to identify multitarget inhibitors of cholinesterases (ChEs) and monoamine oxidase (MAOs) isoforms, we synthesized and…”
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Biochemical and in silico evaluation of a recombinant, glucose tolerant, and highly thermostable β-glucosidase from Thermococcus radiotolerans DSM-15228 by Albalawi, Hayam, Altayeb, Hisham N., Iftikhar, Saima, Al-Ghamdi, Mariam A.A., Khan, Jalaluddin Azam, Nadeem, Muhammad Shahid

“…[Display omitted] β-glucosidase (EC 3.2.1.21) catalyzing the β-glycosidic linkages in polysaccharides is a ubiquitous enzyme with great importance in biofuel…”
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Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domains by Shah, Luqman, Nadeem, Muhammad Shahid, Khan, Jalaluddin Azam, Zeyadi, Mustafa A, Zamzami, Mazin A, Mohammed, Kaleemuddin

“…Glutaminase (GLS) is an enzyme essential for amino acid metabolism; in particular, it acts as a catalyst in glutaminolysis, a reaction exploited by the…”
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COVID-19: Prospective Challenges and Potential Vaccines by Shahid Nadeem, Muhammad, Ali, Akbar, Al-Ghamdi, Maryam A, Depfenhart, Markus, Azam Khan, Jalaluddin, Zamzami, Mazin A, Nazia Murtaza, Bibi, Kazmi, Imran, Ur Rehman, Mujadid

“…RNA viruses exhibit an extraordinary ability to evolve in a changing environment and to switch from animal hosts to humans. The ongoing COVID-19 pandemic,…”
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Recombinant production and biochemical and in silico characterization of lactate dehydrogenase from Geobacillus thermodenitrificans DSM-465 by Nadeem, Muhammad Shahid, Al-Ghamdi, Maryam A., Khan, Jalaluddin Azam, Sadath, Saida, Al-Malki, Abdulaziz

“…Lactate dehydrogenase (LDH) is an enzyme of glycolytic pathway, ubiquitously found in living organisms. Increased glycolysis and LDH activity are associated…”
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Molecular characterisation in tongue squamous cell carcinoma reveals key variants potentially linked to clinical outcomes by Alsofyani, Abeer A, Dallol, Ashraf, Farraj, Suha A, Alsiary, Rawiah A, Samkari, Alaa, Alhaj-Hussain, Baraa T, Khan, Jalaluddin Azam, Al-Maghrabi, Jaudah, Al-Khayyat, Shadi S, Alkhatabi, Heba, Elaimi, Aisha, Buhmeida, Abdelbaset, Johargy, Ayman Khalid, Abuzenadah, Adel M, Azhar, Esam I, Al-Qahtani, Mohammed H

“…Oral tongue squamous cell carcinoma (OTSCC) is a highly aggressive malignancy characterized by frequent recurrence, poor survival with relatively few…”
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Prognostic potential of KLOTHO and SFRP1 promoter methylation in head and neck squamous cell carcinoma by Alsofyani, Abeer A., Alsiary, Rawiah A., Samkari, Alaa, Alhaj-Hussain, Baraa T., Khan, Jalaluddin Azam, Al-Maghrabi, Jaudah, Elaimi, Aisha, Al-Qahtani, Mohammed H., Abuzenadah, Adel M., Dallol, Ashraf

“…Hypermethylation in the CpG island promoter regions of tumor suppressors is known to play a significant role in the development of HNSCC and the detection of…”
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Fluoxetine and sertraline based multitarget inhibitors of cholinesterases and monoamine oxidase-A/B for the treatment of Alzheimer's disease: Synthesis, pharmacology and molecular modeling studies by Nadeem, Muhammad Shahid, Khan, Jalaluddin Azam, Rashid, Umer

“…For the potential therapy of Alzheimer's disease (AD), cholinesterases (ChE) and monoamine oxidase (MAO) are key enzymes that regulate the level of…”
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Synthesis, biological evaluation, molecular docking and dynamic simulation of novel benzofuran derivatives as potential agents against Alzheimer's disease by Nadeem, Muhammad Shahid, Hayat, Shawkat, Rahim, Fazal, Khan, Jalaluddin Azam, Ullah, Hayat, Taha, Muhammad, Gupta, Gaurav, Wadood, Abdul, Shah, Syed Adnan Ali, Kazmi, Imran, Iftikhar, Saima, Muhammad, Khushi

“…•Synthesis of benzofuran derivatives.•In vitro acetylcholinesterase and butyrylcholinesterase inhibitory activity.•Identification of a novel class of…”
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Protective Effect of Hirsutidin against Rotenone-Induced Parkinsonism via Inhibition of Caspase-3/Interleukins‑6 and 1β by Shahid Nadeem, Muhammad, Khan, Jalaluddin Azam, Al-Abbasi, Fahad A., AlGhamdi, Shareefa A., Alghamdi, Amira M., Sayyed, Nadeem, Gupta, Gaurav, Kazmi, Imran

“…A participant of the chemical family recognized as anthocyanins, hirsutidin is an O-methylated anthocyanidin. It is a natural substance, i.e., existing in…”
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Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domainsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ra04740e by Shah, Luqman, Nadeem, Muhammad Shahid, Khan, Jalaluddin Azam, Zeyadi, Mustafa A, Zamzami, Mazin A, Mohammed, Kaleemuddin

“…Glutaminase (GLS) is an enzyme essential for amino acid metabolism; in particular, it acts as a catalyst in glutaminolysis, a reaction exploited by the…”
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