Search Results - "Khan, Abdul Q"
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Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids
Published in Biomedicine & pharmacotherapy (01-11-2021)“…Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of human diseases including cancer. In this line, now it has become…”
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Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies
Published in Cells (Basel, Switzerland) (05-08-2019)“…Recent biomedical discoveries have revolutionized the concept and understanding of carcinogenesis, a complex and multistep phenomenon which involves accretion…”
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3
Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products
Published in Molecular cancer (19-02-2018)“…Tyrosine kinases belong to a family of enzymes that mediate the movement of the phosphate group to tyrosine residues of target protein, thus transmitting…”
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Curcumin-Mediated Apoptotic Cell Death in Papillary Thyroid Cancer and Cancer Stem-Like Cells through Targeting of the JAK/STAT3 Signaling Pathway
Published in International journal of molecular sciences (09-01-2020)“…The constitutive activation of Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) signal transduction is well elucidated in…”
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5
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Published in Molecular cancer (12-03-2020)“…Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients…”
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6
Dynamic liquid biopsy components as predictive and prognostic biomarkers in colorectal cancer
Published in Journal of experimental & clinical cancer research (15-03-2022)“…Colorectal cancer (CRC) is one of the most common cancers worldwide. The diagnosis, prognosis and therapeutic monitoring of CRC depends largely on tissue…”
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Targeting deregulated oxidative stress in skin inflammatory diseases: An update on clinical importance
Published in Biomedicine & pharmacotherapy (01-10-2022)“…Skin, the largest vital organ of the human body, provides the first line of defense against biological, non-biological and xenobiotics exposure. Over the…”
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Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published in Biomedicine & pharmacotherapy (01-12-2021)“…Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options…”
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Exosomes: Emerging Diagnostic and Therapeutic Targets in Cutaneous Diseases
Published in International journal of molecular sciences (04-12-2020)“…Skin is the largest human organ and is continuously exposed to various exogenous and endogenous trigger factors affecting body homeostasis. A number of…”
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Pristimerin mediated anticancer effects and sensitization of human skin cancer cells through modulation of MAPK signaling pathways
Published in Biomedicine & pharmacotherapy (01-12-2022)“…Squamous cell carcinoma is a frequent skin cancer still demanding to understand the underlying mechanisms for better clinical outcomes. Pristimerin, a natural…”
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Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species
Published in Molecules (Basel, Switzerland) (09-03-2020)“…Sanguinarine (SNG), a natural compound with an array of pharmacological activities, has promising therapeutic potential against a number of pathological…”
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Differential response of the cynomolgus macaque gut microbiota to Shigella infection
Published in PloS one (05-06-2013)“…Little is known about the role of gut microbiota in response to live oral vaccines against enteric pathogens. We examined the effect of immunization with an…”
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Corrigendum: Curcumin-mediated degradation of S-phase kinase protein 2 induces cytotoxic effects in human papillomavirus-positive and negative squamous carcinoma cells
Published in Frontiers in oncology (28-09-2023)“…[This corrects the article DOI: 10.3389/fonc.2018.00399.]…”
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Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
Published in Frontiers in oncology (17-04-2019)“…Sanguinarine (SNG), a benzophenanthridine alkaloid, has displayed various anticancer abilities in several vivo and studies. However, the anticancer potential…”
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15
Curcumin-Mediated Degradation of S-Phase Kinase Protein 2 Induces Cytotoxic Effects in Human Papillomavirus-Positive and Negative Squamous Carcinoma Cells
Published in Frontiers in oncology (02-10-2018)“…S-phase kinase-associated protein2 (Skp2), a proto-oncoprotein, plays an important role in development and progression of human malignancies. Skp2 is…”
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Sanguinarine Triggers Apoptosis in Cutaneous Squamous Cell Carcinoma Cells through Reactive Oxygen Species-Dependent c-Jun N-Terminal Kinase Signaling Pathway
Published in Frontiers in bioscience (Landmark. Print) (23-01-2024)“…The benzophenanthridine Sanguinarine (Sng) is one of the most abundant root alkaloids with a long history of investigation and pharmaceutical applications. The…”
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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines
Published in Frontiers in pharmacology (16-07-2018)“…Therapeutic agents used in the treatment of cancer are known to develop resistance against cancer cells. Hence, there is a continuing need to investigate novel…”
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The impact of complications on a programme of enhanced recovery in colorectal surgery
Published in BMC surgery (16-08-2018)“…The advantages of Enhanced Recovery (ER) programmes are well known, in terms of improved overall experience of the patients, which associates with low…”
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Correction to: Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Published in Molecular cancer (29-12-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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20
Concomitant valgus hip osteotomy in operative fixation of displaced proximal femoral neck fractures
Published in Bone & joint open (08-05-2023)“…Total hip arthroplasty (THA) is considered the preferred treatment for displaced proximal femoral neck fractures. However, in many countries this option is…”
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