Search Results - "Khammari, Amir"

The Skin Microbiome: A New Actor in Inflammatory Acne by Dréno, Brigitte, Dagnelie, Marie Ange, Khammari, Amir, Corvec, Stéphane

“…Our understanding of the role of Cutibacterium acnes in the pathophysiology of acne has recently undergone a paradigm shift: rather than C. acnes…”
Get full text

Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab by Martens, Alexander, Wistuba-Hamprecht, Kilian, Geukes Foppen, Marnix, Yuan, Jianda, Postow, Michael A, Wong, Phillip, Romano, Emanuela, Khammari, Amir, Dreno, Brigitte, Capone, Mariaelena, Ascierto, Paolo A, Di Giacomo, Anna Maria, Maio, Michele, Schilling, Bastian, Sucker, Antje, Schadendorf, Dirk, Hassel, Jessica C, Eigentler, Thomas K, Martus, Peter, Wolchok, Jedd D, Blank, Christian, Pawelec, Graham, Garbe, Claus, Weide, Benjamin

“…To identify baseline peripheral blood biomarkers associated with clinical outcome following ipilimumab treatment in advanced melanoma patients. Frequencies of…”
Get full text

Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne by Dreno, Brigitte, Martin, Richard, Moyal, Dominique, Henley, Jessica B., Khammari, Amir, Seité, Sophie

“…Propionibacterium acnes (P. acnes), the sebaceous gland and follicular keratinocytes are considered the three actors involved in the development of acne. This…”
Get full text

Increases in Absolute Lymphocytes and Circulating CD4+ and CD8+ T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab by Martens, Alexander, Wistuba-Hamprecht, Kilian, Yuan, Jianda, Postow, Michael A, Wong, Phillip, Capone, Mariaelena, Madonna, Gabriele, Khammari, Amir, Schilling, Bastian, Sucker, Antje, Schadendorf, Dirk, Martus, Peter, Dreno, Brigitte, Ascierto, Paolo A, Wolchok, Jedd D, Pawelec, Graham, Garbe, Claus, Weide, Benjamin

“…To investigate changes of peripheral blood biomarkers and their impact on clinical outcome following treatment with ipilimumab in advanced melanoma patients…”
Get full text

Bacterial extracellular vesicles: A new way to decipher host‐microbiota communications in inflammatory dermatoses by Dagnelie, Marie‐Ange, Corvec, Stéphane, Khammari, Amir, Dréno, Brigitte

“…Bacterial extracellular vesicles (EVs) are bilayered lipid membrane structures, bearing integral proteins and able to carry diverse cargo outside the cell to…”
Get full text

Decrease in Diversity of Propionibacterium acnes Phylotypes in Patients with Severe Acne on the Back by Dagnelie, Marie-Ange, Corvec, Stéphane, Saint-Jean, Mélanie, Bourdès, Valérie, Nguyen, Jean-Michel, Khammari, Amir, Dréno, Brigitte

“…Propionibacterium acnes, a major member of normal skin microbiota, is subdivided into 6 phylotypes: IA1, IA2, IB, IC, II and III. This study investigated P…”
Get full text

Nanosecond electron pulses in the analytical electron microscopy of a fast irreversible chemical reaction by Sinha, Shyam K., Khammari, Amir, Picher, Matthieu, Roulland, Francois, Viart, Nathalie, LaGrange, Thomas, Banhart, Florian

“…We show how the kinetics of a fast and irreversible chemical reaction in a nanocrystalline material at high temperature can be studied using nanosecond…”
Get full text

Chemotherapy efficacy after first-line immunotherapy in 18 advanced melanoma patients by Saint-Jean, Mélanie, Fronteau, Clémentine, Peuvrel, Lucie, Khammari, Amir, Varey, Emilie, Quéreux, Gaëlle, Dréno, Brigitte

“…In BRAF wild type advanced melanoma, immune checkpoint blockers such as anti-PD1 (anti-programmed cell death 1) are usually continued beyond progression for a…”
Get full text

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion by Fenouille, Nina, Tichet, Mélanie, Dufies, Maeva, Pottier, Anaïs, Mogha, Ariane, Soo, Julia K, Rocchi, Stéphane, Mallavialle, Aude, Galibert, Marie-Dominique, Khammari, Amir, Lacour, Jean-Philippe, Ballotti, Robert, Deckert, Marcel, Tartare-Deckert, Sophie

“…During progression of melanoma, malignant melanocytes can be reprogrammed into mesenchymal-like cells through a process similar to epithelial-mesenchymal…”
Get full text

Double Positive CD4CD8 αβ T Cells: A New Tumor-Reactive Population in Human Melanomas by Desfrançois, Juliette, Moreau-Aubry, Agnès, Vignard, Virginie, Godet, Yann, Khammari, Amir, Dréno, Brigitte, Jotereau, Francine, Gervois, Nadine

“…Background Double positive (DP) CD4CD8 Tαβ cells have been reported in normal individuals as well as in different pathological conditions including…”
Get full text

TLR-2 Recognizes Propionibacterium acnes CAMP Factor 1 from Highly Inflammatory Strains by Lheure, Coralie, Grange, Philippe Alain, Ollagnier, Guillaume, Morand, Philippe, Désiré, Nathalie, Sayon, Sophie, Corvec, Stéphane, Raingeaud, Jöel, Marcelin, Anne-Geneviève, Calvez, Vincent, Khammari, Amir, Batteux, Frédéric, Dréno, Brigitte, Dupin, Nicolas

“…Propionibacterium acnes (P. acnes) is an anaerobic, Gram-positive bacteria encountered in inflammatory acne lesions, particularly in the pilosebaceous…”
Get full text

Phase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients by Dréno, Brigitte, Khammari, Amir, Fortun, Agnès, Vignard, Virginie, Saiagh, Soraya, Beauvais, Tiffany, Jouand, Nicolas, Bercegay, Sylvain, Simon, Sylvain, Lang, François, Labarrière, Nathalie

“…Adoptive cell transfer (ACT) of tumor-specific T lymphocytes represents a relevant therapeutic strategy to treat metastatic melanoma patients. Ideal T-cells…”
Get full text

Quantitative monitoring of circulating tumor DNA predicts response of cutaneous metastatic melanoma to anti-PD1 immunotherapy by Herbreteau, Guillaume, Vallée, Audrey, Knol, Anne-Chantal, Théoleyre, Sandrine, Quéreux, Gaelle, Varey, Emilie, Khammari, Amir, Dréno, Brigitte, Denis, Marc G

“…Immunotherapies have changed the medical management of metastatic melanoma. However, the early detection of patients who do not respond to these treatments is…”
Get full text

Transcriptomic features of tumour-infiltrating CD4lowCD8high double positive αβ T cells in melanoma by Parrot, Tiphaine, Oger, Romain, Allard, Mathilde, Desfrançois, Juliette, Raingeard de la Blétière, Diane, Coutolleau, Anne, Preisser, Laurence, Khammari, Amir, Dréno, Brigitte, Delneste, Yves, Guardiola, Philippe, Fradin, Delphine, Gervois, Nadine

“…Peripheral CD4 + CD8 + double positive (DP) T cells are a phenotypically and functionally heterogeneous population depending on their origin and pathologic…”
Get full text

In vitro modulation of TLR-2, CD1d and IL-10 by adapalene on normal human skin and acne inflammatory lesions by Tenaud, Isabelle, Khammari, Amir, Dreno, Brigitte

“…The anti‐inflammatory mechanisms of adapalene, a synthetic retinoid used for the treatment of acne patients, are partially understood. They seem particularly…”
Get full text

An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial by Charles, Julie, Chaperot, Laurence, Hannani, Dalil, Bruder Costa, Juliana, Templier, Isabelle, Trabelsi, Sabiha, Gil, Hugo, Moisan, Anaick, Persoons, Virginie, Hegelhofer, Harald, Schir, Edith, Quesada, Jean-Louis, Mendoza, Christophe, Aspord, Caroline, Manches, Olivier, Coulie, Pierre G., Khammari, Amir, Dreno, Brigitte, Leccia, Marie-Thérèse, Plumas, Joel

“…The efficacy of immune checkpoint inhibitors has been shown to depend on preexisting antitumor immunity; thus, their combination with cancer vaccines is an…”
Get full text

Histopathological aspects of cutaneous erythematous‐papular eruptions induced by immune checkpoint inhibitors for the treatment of metastatic melanoma by Perret, Raul E., Josselin, Nicolas, Knol, Anne‐Chantal, Khammari, Amir, Cassecuel, Julie, Peuvrel, Lucie, Dreno, Brigitte

“…Background Immune checkpoint blockade therapy (ICBT) for the treatment of melanoma has led to an important improvement of overall survival in advanced stage…”
Get full text

Emergence of High-Avidity Melan-A-Specific Clonotypes as a Reflection of Anti-PD-1 Clinical Efficacy by Simon, Sylvain, Vignard, Virginie, Varey, Emilie, Parrot, Tiphaine, Knol, Anne-Chantal, Khammari, Amir, Gervois, Nadine, Lang, Francois, Dreno, Brigitte, Labarriere, Nathalie

“…Therapeutic strategies using anti-PD-1-blocking antibodies reported unparalleled effectiveness for melanoma immunotherapy, but deciphering immune responses…”
Get full text

PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy by Simon, Sylvain, Voillet, Valentin, Vignard, Virginie, Wu, Zhong, Dabrowski, Camille, Jouand, Nicolas, Beauvais, Tiffany, Khammari, Amir, Braudeau, Cécile, Josien, Régis, Adotevi, Olivier, Laheurte, Caroline, Aubin, François, Nardin, Charles, Rulli, Samuel, Gottardo, Raphael, Ramchurren, Nirasha, Cheever, Martin, Fling, Steven P, Church, Candice D, Nghiem, Paul, Dreno, Brigitte, Riddell, Stanley R, Labarriere, Nathalie

“…BackgroundClinical benefit from programmed cell death 1 receptor (PD-1) inhibitors relies on reinvigoration of endogenous antitumor immunity. Nonetheless,…”
Get full text

Circulating Tumor DNA Early Kinetics Predict Response of Metastatic Melanoma to Anti-PD1 Immunotherapy: Validation Study by Herbreteau, Guillaume, Vallée, Audrey, Knol, Anne-Chantal, Théoleyre, Sandrine, Quéreux, Gaëlle, Varey, Emilie, Khammari, Amir, Dréno, Brigitte, Denis, Marc G

“…The ability of early (first weeks of treatment) ctDNA kinetics to identify primary resistance to anti-PD1 immunotherapies was evaluated with a validation…”
Get full text