Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis

The article describes a clinical case of a rare combination of hereditary pathology – Gaucher disease and latent tuberculosis infection in an 8-year-old child. The child was examined for tuberculosis due to disseminated small foci and calcination in the lung tissue detected by chest computed tomogra...

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Bibliographic Details
Published in:Tuberkulëz i bolezni lëgkikh Vol. 98; no. 10; pp. 47 - 51
Main Authors: Lozovskaya, M. E., Yarovaya, Yu. A., Vasilieva, E. В., Khamchieva, L. N., Mosina, A. V., Gavrilov, P. V.
Format: Journal Article
Language:English
Russian
Published: New Terra Publishing House 14-11-2020
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Summary:The article describes a clinical case of a rare combination of hereditary pathology – Gaucher disease and latent tuberculosis infection in an 8-year-old child. The child was examined for tuberculosis due to disseminated small foci and calcination in the lung tissue detected by chest computed tomography. The particular parameter of latent tuberculosis infection of this case was the positive results of IGRA tests (T-SPOT TB and QuantiFERON) with a negative response to the intradermal test with recombinant tuberculosis allergen. According to the examination results, the disseminated tuberculosis was not confirmed, diffuse lung damage was regarded as a manifestation of Gaucher disease, which was a rare sign of this pathology according to the published data.
ISSN:2075-1230
2542-1506
DOI:10.21292/2075-1230-2020-98-10-47-51