Search Results - "Khalili Ghomi, Minoo"

New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: design, synthesis, in vitro inhibition, and molecular dynamic simulation by Dastyafteh, Navid, Noori, Milad, Nazari Montazer, Mohammad, Zomorodian, Kamiar, Yazdanpanah, Somayeh, Iraji, Aida, Khalili Ghomi, Minoo, Javanshir, Shahrzad, Asadi, Mehdi, Dianatpour, Mehdi, Biglar, Mahmood, Larijani, Bagher, Amanlou, Massoud, Mahdavi, Mohammad

“…To identify potent urease inhibitors, in the current study, a series of thioxothiazolidinyl-acetamides were designed and synthesized. The prepared compounds…”
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[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as new therapeutic candidates against urease positive microorganisms: design, synthesis, pharmacological evaluations, and in silico studies by Khalili Ghomi, Minoo, Noori, Milad, Nazari Montazer, Mohammad, Zomorodian, Kamiar, Dastyafteh, Navid, Yazdanpanah, Somayeh, Sayahi, Mohammad Hosein, Javanshir, Shahrzad, Nouri, Abbas, Asadi, Mehdi, Badali, Hamid, Larijani, Bagher, Irajie, Cambyz, Iraji, Aida, Mahdavi, Mohammad

“…Regarding the important role of the urease enzyme as a virulence factor in urease-positive microorganisms in this study, new series of…”
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Aryl-quinoline-4-carbonyl hydrazone bearing different 2-methoxyphenoxyacetamides as potent α-glucosidase inhibitors; molecular dynamics, kinetic and structure–activity relationship studies by Hamedifar, Haleh, Mirfattahi, Mahroo, Khalili Ghomi, Minoo, Azizian, Homa, Iraji, Aida, Noori, Milad, Moazzam, Ali, Dastyafteh, Navid, Nokhbehzaim, Ali, Mehrpour, Katayoun, Javanshir, Shahrzad, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Larijani, Bagher, Hajimiri, Mir Hamed, Mahdavi, Mohammad

“…Regarding the important role of α-glucosidase enzyme in the management of type 2 diabetes mellitus, the current study was established to design and synthesize…”
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Synthesis and bioactivities evaluation of quinazolin-4(3H)-one derivatives as α-glucosidase inhibitors by Moheb, Mahshid, Iraji, Aida, Dastyafteh, Navid, Khalili Ghomi, Minoo, Noori, Milad, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Rasekh, Fatemeh, Larijani, Bagher, Zomorodian, Kamiar, Sadat-Ebrahimi, Seyed Esmaeil, Mahdavi, Mohammad

“…The development of new antidiabetes agents is necessary to obtain optimal glycemic control and overcome its complications. Different quinazolin-4(3 H )-one…”
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Synthesis, in vitro potency of inhibition, enzyme kinetics and in silico studies of quinoline-based α-glucosidase inhibitors by Ghomi, Minoo Khalili, Dastyafteh, Navid, Montazer, Mohammad Nazari, Noori, Milad, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Hashemi, Seyedeh Mahdieh, Mahdavi, Mohammad

“…Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate. One effective therapeutic approach for controlling…”
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Synthesis and structure–activity relationship studies of benzimidazole-thioquinoline derivatives as α-glucosidase inhibitors by Moghadam Farid, Sara, Noori, Milad, Nazari Montazer, Mohammad, Khalili Ghomi, Minoo, Mollazadeh, Marjan, Dastyafteh, Navid, Irajie, Cambyz, Zomorodian, Kamiar, Mirfazli, Seyedeh Sara, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Larijani, Bagher, Iraji, Aida, Mahdavi, Mohammad

“…In this article, different s-substituted benzimidazole-thioquinoline derivatives were designed, synthesized, and evaluated for their possible α-glucosidase…”
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Synthesis, in vitro inhibitor screening, structure–activity relationship, and molecular dynamic simulation studies of novel thioquinoline derivatives as potent α-glucosidase inhibitors by Forozan, RasaDokht, Ghomi, Minoo Khalili, Iraji, Aida, Montazer, Mohammad Nazari, Noori, Milad, Dastyafteh, Navid, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Sadat-Ebrahimi, Seyed Esmaeil, Larijani, Bagher, Javanshir, Shahrzad, Mahdavi, Mohammad

“…New series of thioquinoline structures bearing phenylacetamide 9a – p were designed, synthesized and the structure of all derivatives was confirmed using…”
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Evaluation of novel 2-(quinoline-2-ylthio)acetamide derivatives linked to diphenyl-imidazole as α-glucosidase inhibitors: Insights from in silico, in vitro, and in vivo studies on their anti-diabetic properties by Khalili Ghomi, Minoo, Noori, Milad, Mirahmad, Maryam, Iraji, Aida, Sadr, Ahmad Shahir, Dastyafteh, Navid, Asili, Pooria, Gholami, Mahdi, Javanshir, Shahrzad, Lotfi, Maryam, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Asadi, Mehdi, Nasli-Esfahani, Ensieh, Palimi, Mahdie, Larijani, Bagher, Meshkatalsadat, Mohammad Hadi, Mahdavi, Mohammad

“…The inhibition of the α-glucosidase enzyme is crucial for targeting type 2 diabetes mellitus (DM). This study introduces a series of synthetic analogs based on…”
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Phenyl-quinoline derivatives as lead structure of cholinesterase inhibitors with potency to reduce the GSK-3β level targeting Alzheimer's disease by Noori, Milad, Dastyafteh, Navid, Safapoor, Sajedeh, Khalili Ghomi, Minoo, Tanideh, Romina, Zomorodian, Kamiar, Hamedifar, Haleh, Dara, Mahintaj, Zare, Shahrokh, Irajie, Cambyz, Javanshir, Shahrzad, Rastegar, Hossein, Panahi, Nikoo, Larijani, Bagher, Mahdavi, Mohammad, Hajimiri, Mir H., Iraji, Aida

“…Alzheimer's disease (AD) is a neurodegenerative disorder that leads to cognitive decline and memory loss. Unfortunately, there is no effective treatment for…”
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Thioquinoline derivatives conjugated to thiosemicarbazide as potent tyrosinase inhibitors with anti-melanogenesis properties by Noori, Milad, Sabourian, Reyhaneh, Tasharoie, Ali, Safavi, Maliheh, Iraji, Aida, Khalili Ghomi, Minoo, Dastyafteh, Navid, Irajie, Cambyz, Zarenezhad, Elham, Mostafavi Pour, Seyyed Mehrdad, Rasekh, Fatemeh, Larijani, Bagher, Amini, Mohsen, Hajimahmoodi, Mannan, Mahdavi, Mohammad

“…In the present study, a series of aryl-substituted thioqunoline conjugated to thiosemicarbazide were rationally designed and synthesized. The formation of…”
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Alpha-glucosidase inhibitory and hypoglycemic effects of imidazole-bearing thioquinoline derivatives with different substituents: In silico, in vitro, and in vivo evaluations by Azmi, Anita, Noori, Milad, Khalili Ghomi, Minoo, Nazari Montazer, Mohammad, Iraji, Aida, Dastyafteh, Navid, Oliyaei, Najmeh, Khoramjouy, Mona, Rezaei, Zahra, Javanshir, Shahrzad, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Asadi, Mehdi, Faizi, Mehrdad, Mahdavi, Mohammad

“…[Display omitted] •A series of imidazole bearing different substituted thioquinolines were synthesized as α-glucosidase inhibitors.•All derivatives exhibited…”
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Synthesis, ADMT prediction, and in vitro and in silico α-glucosidase inhibition evaluations of new quinoline-quinazolinone-thioacetamides by Safapoor, Sajedeh, Halimi, Mohammad, Ghomi, Minoo Khalili, Noori, Milad, Dastyafteh, Navid, Javanshir, Shahrzad, Hosseini, Samanesadat, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Nasli-Esfahani, Ensieh, Larijani, Bagher, Fakhrioliaei, Azadeh, Dekamin, Mohammad G, Mohammadi-Khanaposhtani, Maryam, Mahdavi, Mohammad

“…In this work, a new series of quinoline-quinazolinone-thioacetamide derivatives 9a-p were designed using a combination of effective pharmacophores of the…”
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Method for the synthesis of chromenopyrimidine-fused azoles by copper-catalyzed intramolecular hetero-Diels–Alder reaction by Ghomi, Minoo Khalili, Alizadeh, Naeimeh, Moazzam, Ali, Hosseini, Samanesadat, Bahadorikhalili, Saeed, Larijani, Bagher, Mahdavi, Mohammad

“…One-pot efficient copper-catalyzed approach for the synthesis of tetracyclic chromeno[4',3':4,5]pyrimido[1,2- b ]indazolone and chromeno[4,3- d…”
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Design, synthesis, in vitro, and in silico enzymatic evaluations of thieno[2,3-b]quinoline-hydrazones as novel inhibitors for α-glucosidase by Noori, Milad, Rastak, Mryam, Halimi, Mohammad, Ghomi, Minoo Khalili, Mollazadeh, Mrjan, Mohammadi-Khanaposhtani, Maryam, Sayahi, Mohammad Hosein, Rezaei, Zahra, Mojtabavi, Somayeh, Ali Faramarzi, Mohammad, Larijani, Bagher, Biglar, Mahmood, Amanlou, Massoud, Mahdavi, Mohammad

“…Design, synthesis, in vitro, and in silico enzymatic evaluations of thieno[2,3-b]quinoline-hydrazones as novel inhibitors for α-glucosidase. [Display omitted]…”
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Copper supported modified magnetic carrageenan as a bio-based catalyst for the synthesis of novel scaffolds bearing the 1,2,3-triazole unit through the click reaction by Khaleghi, Nima, Esmkhani, Maryam, Noori, Milad, Dastyafteh, Navid, Ghomi, Minoo Khalili, Mahdavi, Mohammad, Sayahi, Mohammad Hosein, Javanshir, Shahrzad

“…The ongoing work delineates the design of a novel library of 1,2,3-triazole-attached phenylacetamides through molecular hybridization of propargyl and…”
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Isoindolinedione-Benzamide Pyridinium Derivatives for Targeting Alzheimer’s Disease by Noori, Milad, Khalili Ghomi, Minoo, Dastyafteh, Navid, Oliyaei, Najmeh, Hamedifar, Haleh, Javanshir, Shahrzad, Tanideh, Nader, Sattarinezhad, Elahe, Sattari, Fateme, Haghani, Masoud, Rahmani, Hojjat, Larijani, Bagher, Mahdavi, Mohammad, Hajimiri, Mir H., Iraji, Aida

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Synthesis and bioactivities evaluation of quinazolin-4-one derivatives as [alpha]-glucosidase inhibitors by Moheb, Mahshid, Iraji, Aida, Dastyafteh, Navid, Khalili Ghomi, Minoo, Noori, Milad, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Rasekh, Fatemeh, Larijani, Bagher, Zomorodian, Kamiar, Sadat-Ebrahimi, Seyed Esmaeil, Mahdavi, Mohammad

“…The development of new antidiabetes agents is necessary to obtain optimal glycemic control and overcome its complications. Different quinazolin-4(3H)-one…”
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Synthesis, ADMT prediction, and and α-glucosidase inhibition evaluations of new quinoline-quinazolinone-thioacetamides by Safapoor, Sajedeh, Halimi, Mohammad, Ghomi, Minoo Khalili, Noori, Milad, Dastyafteh, Navid, Javanshir, Shahrzad, Hosseini, Samanesadat, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Nasli-Esfahani, Ensieh, Larijani, Bagher, Fakhrioliaei, Azadeh, Dekamin, Mohammad G, Mohammadi-Khanaposhtani, Maryam, Mahdavi, Mohammad

“…In this work, a new series of quinoline-quinazolinone-thioacetamide derivatives 9a-p were designed using a combination of effective pharmacophores of the…”
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Synthesis, α‐glucosidase Inhibition, in silico Pharmacokinetic, and Docking Studies Of Thieno[2,3‐b]Quinoline‐Acetamide Derivatives as New Anti‐Diabetic Agents by Mohammadi‐Khanaposhtani, Maryam, Noori, Milad, Valizadeh, Yousef, Dastyafteh, Navid, Ghomi, Minoo Khalili, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Hosseini, Samanesadat, Biglar, Mahmood, Larijani, Bagher, Rastegar, Hossein, Hamedifar, Haleh, Mirzazadeh, Roghieh, Mahdavi, Mohammad

“…In this work, novel anti‐α‐glucosidase agents, thieno[2,3‐b]quinoline‐acetamide derivatives 5 a–m have been designed and synthesized. These compounds were…”
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