Search Results - "Khalili, Saeed"
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A cell ELISA based method for exosome detection in diagnostic and therapeutic applications
Published in Biotechnology letters (01-05-2019)“…Objective Exosomes are nano-scaled carriers of miRNA, mRNA and proteins which are secreted from viable cells. Exosome detection within serum, saliva and semen…”
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Specific egg yolk immunoglobulin as a promising non-antibiotic biotherapeutic product against Acinetobacter baumannii pneumonia infection
Published in Scientific reports (21-01-2021)“…Acinetobacter baumannii is a serious health threat with a high mortality rate. We have already reported prophylactic effects of IgYs raised against OmpA and…”
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Editorial: Recent advances in the development of vaccines against Acinetobacter baumannii
Published in Frontiers in immunology (31-05-2023)Get full text
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Hotspots for mutations in the SARS-CoV-2 spike glycoprotein: a correspondence analysis
Published in Scientific reports (08-12-2021)“…Spike glycoprotein (Sgp) is liable for binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the host receptors. Since Sgp is the main…”
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SARS-CoV-2 Proteome Harbors Peptides Which Are Able to Trigger Autoimmunity Responses: Implications for Infection, Vaccination, and Population Coverage
Published in Frontiers in immunology (10-08-2021)“…Autoimmune diseases (ADs) could occur due to infectious diseases and vaccination programs. Since millions of people are expected to be infected with SARS-CoV-2…”
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A unique antigen against SARS-CoV-2, Acinetobacter baumannii, and Pseudomonas aeruginosa
Published in Scientific reports (27-06-2022)“…The recent outbreak of COVID-19 has increased hospital admissions, which could elevate the risk of nosocomial infections, such as A. baumannii and P…”
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In silico Validation of Pseudomonas aeruginosa Exotoxin A Domain I Interaction with the Novel Human scFv Antibody
Published in Infectious disorders drug targets (2023)“…Pseudomonas (P.) aeruginosa is one of the leading causes of nosocomial infections. The pathogenicity of P. aeruginosa is related to its inherent antimicrobial…”
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Impact of SNPs, off-targets, and passive permeability on efficacy of BCL6 degrading drugs assigned by virtual screening and 3D-QSAR approach
Published in Scientific reports (06-12-2022)“…B-cell lymphoma 6 (BCL6) regulates various genes and is reported to be overexpressed in lymphomas and other malignancies. Thus, BCL6 inhibition or its tagging…”
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Distinctive Expression of MetastamiRs in Breast Cancer Mesenchymal Stem Cells Isolated from Solid Tumor
Published in Current stem cell research & therapy (01-01-2024)“…MSCs are a part of the tumor microenvironment, which secrete cytokines and chemokines. They can affect metastasis and the growth of tumors. metastamiRs are…”
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A general rule for uniqueness in self‐modeling curve resolution methods
Published in Journal of chemometrics (01-07-2020)“…Self‐modeling curve resolution (SMCR) techniques are widely applied for resolving chemical data to the pure‐component spectra and composition profiles. In most…”
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Deciphering crucial genes in coeliac disease by bioinformatics analysis
Published in Autoimmunity (Chur, Switzerland) (17-02-2020)“…Coeliac disease (CD) is a chronic autoimmune disease that is characterized by malabsorption in sensitive individuals. CD is triggered by the ingestion of…”
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In silico Approaches for the Design and Optimization of Interfering Peptides Against Protein-Protein Interactions
Published in Frontiers in molecular biosciences (28-04-2021)“…Large contact surfaces of protein-protein interactions (PPIs) remain to be an ongoing issue in the discovery and design of small molecule modulators. Peptides…”
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Clodronic Acid has Strong Inhibitory Interactions with the Urease Enzyme of Helicobacter pylori : Computer-aided Design and in vitro Confirmation
Published in Current computer-aided drug design (01-01-2024)“…(HP) infection could lead to various gastrointestinal diseases. Urease is the most important virulence factor of HP. It protects the bacterium against gastric…”
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Current understanding of epigenetics role in melanoma treatment and resistance
Published in Cancer cell international (12-10-2022)“…Melanoma is the most aggressive form of skin cancer resulting from genetic mutations in melanocytes. Several factors have been considered to be involved in…”
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Mesenchymal stromal cells improve salivary function and reduce lymphocytic infiltrates in mice with Sjögren's-like disease
Published in PloS one (07-06-2012)“…Non-obese diabetic (NOD) mice develop Sjögren's-like disease (SS-like) with loss of saliva flow and increased lymphocytic infiltrates in salivary glands (SGs)…”
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Non-adaptive Evolution of Trimeric Autotransporters in Brucellaceae
Published in Frontiers in microbiology (12-11-2020)“…species are Gram-negative, facultative intracellular pathogens. They are the main cause of brucellosis, which has led to a global health burden. Adherence of…”
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Paracrine effects of bone marrow soup restore organ function, regeneration, and repair in salivary glands damaged by irradiation
Published in PloS one (24-04-2013)“…There are reports that bone marrow cell (BM) transplants repaired irradiated salivary glands (SGs) and re-established saliva secretion. However, the mechanisms…”
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Tumor Necrosis Factor-α and Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome
Published in Mediators of Inflammation (01-01-2013)“…Obesity has become a worldwide health burden in the last two decades. Obesity has been associated with increased comorbidities, such as coronary artery…”
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Harnessing an Integrative In Silico Approach to Engage Highly Immunogenic Peptides in an Antigen Design Against Epsilon Toxin (ETX) of Clostridium perfringens
Published in International journal of peptide research and therapeutics (01-06-2021)“…Epsilon toxin (ETX) is one of four lethal toxins of Clostridium perfringens produced by types B and D of the pathogen. This pore-forming toxin is one of the…”
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Additive effect of metastamiR-193b and breast cancer metastasis suppressor 1 as an anti-metastatic strategy
Published in Breast cancer (Tokyo, Japan) (01-03-2019)“…Background It has been reported that enhancing the cellular levels of miR-193b as well as breast cancer-metastasis-suppressor-1 (BRMS1) protein is associated…”
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