Search Results - "Khalil, Najeh Maissar"

Imbalanced testicular metabolism induced by thyroid disorders: New evidences from quantitative proteome by Nascimento Gomes, Samantha, do Carmo Corrêa, Deborah Elzita, de Oliveira, Isabela Medeiros, Bargi-Souza, Paula, Degraf Cavallin, Monica, Dobner Mariano, Danielle, Maissar Khalil, Najeh, Alves Figueiredo, David Livingstone, Romano, Marco Aurelio, de Oliveira, Claudio Alvarenga, Marino Romano, Renata

“…Thyroid dysfunctions, such as hypothyroidism and hyperthyroidism, are the second most prevalent endocrinopathies and are associated to reproductive disorders…”
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A stability-indicating high performance liquid chromatography method to determine apocynin in nanoparticles by de Oliveira, Juliana Kovalczuk, Ronik, Débora Fernanda Veres, Ascari, Jociani, Mainardes, Rubiana Mara, Khalil, Najeh Maissar

“…In this study, we developed and validated a fast, specific, sensitive, precise and stability-indicating high performance liquid chromatography（HPLC） method to…”
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Mucoadhesive nanoemulsion enhances brain bioavailability of luteolin after intranasal administration and induces apoptosis to SH-SY5Y neuroblastoma cells by Diedrich, Camila, Camargo Zittlau, Isabella, Schineider Machado, Christiane, Taise Fin, Margani, Maissar Khalil, Najeh, Badea, Ildiko, Mara Mainardes, Rubiana

“…[Display omitted] Neuroblastoma is the most frequently diagnosed extracranial solid tumor in children and accounts for 7 % of all childhood malignancies and…”
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Exploring the Role of Nanoparticles in Amphotericin B Delivery by Zaioncz, Soraia, Khalil, Najeh Maissar, Mainardes, Rubiana Mara

“…Amphotericin B (AmB) is the drug of choice in the treatment of invasive fungal infections and visceral leishmaniasis. Although AmB has a higher selectivity for…”
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Pharmacokinetics of curcumin-loaded PLGA and PLGA–PEG blend nanoparticles after oral administration in rats by Khalil, Najeh Maissar, Nascimento, Thuane Castro Frabel do, Casa, Diani Meza, Dalmolin, Luciana Facco, Mattos, Ana Cristina de, Hoss, Ivonete, Romano, Marco Aurélio, Mainardes, Rubiana Mara

“…[Display omitted] ► Curcumin was loaded in PLGA and PLGA–PEG blend nanoparticles. ► The nanoparticles prolonged extensively the curcumin release. ► All…”
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Bovine serum albumin-based nanoparticles containing the flavonoid rutin produced by nano spray drying by Pedrozo, Regiellen Cristina, Antônio, Emilli, Khalil, Najeh Maissar, Mainardes, Rubiana Mara

“…Rutin is a flavonoid compound obtained from different vegetables and fruits; specifically, it is found in the seeds of buckwheat and in fruit peels,…”
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Polyethylene Glycol-Stabilized Zein Nanoparticles Containing Gallic Acid by Wiggers, Heliton Augusto, Fin, Margani Taise, Khalil, Najeh Maissar, Mainardes, Rubiana Mara

“…Research background. Gallic acid is a polyphenol with antioxidant and antitumor activities; however, its use as a nutraceutical or drug is hindered by its low…”
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Nanoparticles as a Tool for Broadening Antifungal Activities by Renzi, Daniele Fernanda, de Almeida Campos, Laís, Miranda, Eduardo Hösel, Mainardes, Rubiana Mara, Abraham, Wolf-Rainer, Grigoletto, Diana Fortkamp, Khalil, Najeh Maissar

“…Fungal infections are diseases that are considered neglected although their infection rates have increased worldwide in the last decades. Thus, since the…”
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Application of a validated HPLC-PDA method for the determination of melatonin content and its release from poly(lactic acid) nanoparticles by Martins, Leiziani Gnatkowski, khalil, Najeh Maissar, Mainardes, Rubiana Mara

“…Melatonin is a natural hormone and with the advancement of age its production declines and thereby may result in some neurological disorders. Exogenous…”
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Curcumin antifungal and antioxidant activities are increased in the presence of ascorbic acid by Khalil, Omar Arafat Kdudsi, de Faria Oliveira, Olga Maria Mascarenhas, Vellosa, José Carlos Rebuglio, de Quadros, Andreza Urba, Dalposso, Loriangela Marceli, Karam, Thaysa Ksiaskiewcz, Mainardes, Rubiana Mara, Khalil, Najeh Maissar

“…► Curcumin and ascorbic acid were associated. ► Antifungal activity of isolated and associated compounds was analysed. ► Antioxidant activity of isolated and…”
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Exploring Cationic Guar Gum: Innovative Hydrogels and Films for Enhanced Wound Healing by Dallabrida, Kamila Gabrieli, Braz, Willer Cezar, Marchiori, Crisleine, Alves, Thainá Mayer, Cruz, Luiza Stolz, Trindade, Giovanna Araujo de Morais, Machado, Patrícia, da Rosa, Lucas Saldanha, Khalil, Najeh Maissar, Rego, Fabiane Gomes de Moraes, Fajardo, André Ricardo, Ferreira, Luana Mota, Sari, Marcel Henrique Marcondes, Reolon, Jéssica Brandão

“…This study developed and characterized hydrogels (HG-CGG) and films (F-CGG) based on cationic guar gum (CGG) for application in wound healing. HG-CGG (2% / )…”
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Optimized Chitosan-Coated Gliadin Nanoparticles Improved the Hesperidin Cytotoxicity over Tumor Cells by Kelte Filho, Irineo, Machado, Christiane Schineider, Diedrich, Camila, Karam, Thaysa Ksiaskiewcz, Nakamura, Celso Vataru, Khalil, Najeh Maissar, Mainardes, Rubiana Mara

“…Abstract Hesperidin is a natural compound which is found in citric fruits and presents antitumor and antimicrobial activities. However, the in vivo efficacy of…”
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Zidovudine-loaded PLA and PLA-PEG blend nanoparticles: influence of polymer type on phagocytic uptake by polymorphonuclear cells by Mainardes, Rubiana Mara, Gremião, Maria Palmira Daflon, Brunetti, Iguatemy Lourenço, da Fonseca, Luiz Marcos, Khalil, Najeh Maissar

“…Mononuclear (macrophages) and polymorphonuclear leucocytes cells play an important role in the immunopathogenesis of acquired immunodeficiency syndrome…”
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Nanotechnology-Based Approaches for Voriconazole Delivery Applied to Invasive Fungal Infections by de Almeida Campos, Laís, Fin, Margani Taise, Santos, Kelvin Sousa, de Lima Gualque, Marcos William, Freire Cabral, Ana Karla Lima, Khalil, Najeh Maissar, Fusco-Almeida, Ana Marisa, Mainardes, Rubiana Mara, Mendes-Giannini, Maria José Soares

“…Invasive fungal infections increase mortality and morbidity rates worldwide. The treatment of these infections is still limited due to the low bioavailability…”
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Nanotechnological strategies for the treatment of neglected diseases by Khalil, Najeh Maissar, de Mattos, Ana Cristina, Carraro, Talita Cristina Moraes Moreira, Ludwig, Daniel Brustolin, Mainardes, Rubiana Mara

“…Neglected diseases are prevalent in less developed countries and are associated with high levels of mortality and/or morbidity. The drugs used in clinical…”
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Resveratrol-Loaded Polymeric Nanoparticles: Validation of an HPLC-PDA Method to Determine the Drug Entrapment and Evaluation of Its Antioxidant Activity by da Rocha Lindner, Gabriela, Mainardes, Rubiana Mara, Khalil, Najeh Maissar

“…Poly(lactic acid) (PLA) and PLA-poly(ethylene glycol) (PLA-PEG) nanoparticles containing resveratrol (RVT) were developed, and their antioxidant activity was…”
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Effect of the Isocoumarin Paepalantine on the Luminol and Lucigenin Amplified Chemiluminescence of Rat Neutrophils by Kitagawa, Rodrigo Rezende, Raddi, Maria Stella Gonçalves, Khalil, Najeh Maissar, Vilegas, Wagner, Fonseca, Luiz Marcos da

“…Paepalantine (9,10-dihydroxy-5,7-dimethoxy-1H-naphto(2,3c)pyran-1-one), a natural isocoumarin isolated from the capitula of Paepalanthus bromelioides…”
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PHBV/PCL Microparticles for Controlled Release of Resveratrol: Physicochemical Characterization, Antioxidant Potential, and Effect on Hemolysis of Human Erythrocytes by Farago, Paulo Vitor, Mainardes, Rubiana Mara, Khalil, Najeh Maissar, Stulzer, Hellen Karine, Michel, Milton Domingos, de Oliveira, Viviane Matoso, Riekes, Manoela Klüppel, Mendes, Jessica Bitencourt Emilio, Zawadzki, Sônia Faria

“…Microparticles of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and poly(ε-caprolactone) (PCL) containing resveratrol were successfully prepared by…”
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A stability-indicating HPLC-PDA method for the determination of ferulic acid in chitosan-coated poly(lactide-co-glycolide) nanoparticles by Lima, Isabela Angeli de, Khalil, Najeh Maissar, Mainardes, Rubiana Mara

“…The development and validation of a simple and efficient method for the quantification of ferulic acid in poly (D,L-lactide-co-glycolide) (PLGA) nanoparticles…”
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Development and validation of an HPLC method for the determination of fluorouracil in polymeric nanoparticles by Mattos, Ana Cristina de, Khalil, Najeh Maissar, Mainardes, Rubiana Mara

“…The objective of this work was to develop and validate a rapid high performance liquid chromatography (HPLC) method for the quantitative analysis of…”
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