Search Results - "Khalil, Michael"
-
1
Serum neurofilament light levels in normal aging and their association with morphologic brain changes
Published in Nature communications (10-02-2020)“…Neurofilament light (NfL) protein is a marker of neuro-axonal damage and can be measured not only in cerebrospinal fluid but also in serum, which allows for…”
Get full text
Journal Article -
2
Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients
Published in Journal of neuroinflammation (20-01-2022)“…Comprehensive data on the cerebrospinal fluid (CSF) profile in patients with COVID-19 and neurological involvement from large-scale multicenter studies are…”
Get full text
Journal Article -
3
Redox State of Human Serum Albumin in Multiple Sclerosis: A Pilot Study
Published in International journal of molecular sciences (13-12-2022)“…Like in many other pathologies, oxidative stress is involved in the development of neurodegenerative disorders. Human serum albumin (HSA) is the main protein…”
Get full text
Journal Article -
4
Consensus guidelines for lumbar puncture in patients with neurological diseases
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2017)“…Abstract Introduction Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic workup of several neurological brain diseases…”
Get full text
Journal Article -
5
Low-frequency MR elastography reveals altered deep gray matter viscoelasticity in multiple sclerosis
Published in NeuroImage clinical (01-01-2024)“…[Display omitted] •Low-frequency MRE reveals altered deep gray matter viscoelasticity in MS patients.•Thalamic viscoelasticity is changed in MS independent of…”
Get full text
Journal Article -
6
Serum Neurofilament Light Chain as Biomarker for Cladribine-Treated Multiple Sclerosis Patients in a Real-World Setting
Published in International journal of molecular sciences (01-02-2023)“…Serum neurofilament light chain (sNfL) is an intensely investigated biomarker in multiple sclerosis (MS). The aim of this study was to explore the impact of…”
Get full text
Journal Article -
7
Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview
Published in Alzheimer's & dementia (01-10-2022)“…Introduction The current practice of quantifying cerebrospinal fluid (CSF) biomarkers as an aid in the diagnosis of Alzheimer's disease (AD) varies from center…”
Get full text
Journal Article -
8
Higher education moderates the effect of T2 lesion load and third ventricle width on cognition in multiple sclerosis
Published in PloS one (27-01-2014)“…Previous work suggested greater intellectual enrichment might moderate the negative impact of brain atrophy on cognition. This awaits confirmation in…”
Get full text
Journal Article -
9
CD19+IgD+CD27- Naïve B Cells as Predictors of Humoral Response to COVID 19 mRNA Vaccination in Immunocompromised Patients
Published in Frontiers in immunology (07-12-2021)“…Immunocompromised patients are considered high-risk and prioritized for vaccination against COVID-19. We aimed to analyze B-cell subsets in these patients to…”
Get full text
Journal Article -
10
An AI Based Automatic Translator for Ancient Hieroglyphic Language - From Scanned Images to English Text
Published in IEEE access (01-01-2023)“…Recent advancements in the fields of Machine Learning and Deep Learning made a huge transformation in other fields that are not related to Computer Science. In…”
Get full text
Journal Article -
11
Patterns of antibody binding to aquaporin-4 isoforms in neuromyelitis optica
Published in PloS one (05-05-2010)“…Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself with optic neuritis and longitudinally extensive transverse myelitis. Serum…”
Get full text
Journal Article -
12
Coenzyme A fueling with pantethine limits autoreactive T cell pathogenicity in experimental neuroinflammation
Published in Journal of neuroinflammation (05-11-2024)“…Abstract Background Immune cell metabolism governs the outcome of immune responses and contributes to the development of autoimmunity by controlling lymphocyte…”
Get full text
Journal Article -
13
Multimodal assessment of white matter tracts in amyotrophic lateral sclerosis
Published in PloS one (02-06-2017)“…Several quantitative magnetic resonance imaging (MRI) techniques have been proposed to investigate microstructural tissue changes in amyotrophic lateral…”
Get full text
Journal Article -
14
Vitamin D-An Effective Antioxidant in an Animal Model of Progressive Multiple Sclerosis
Published in Nutrients (26-07-2023)“…Vitamin D (VD) is the most discussed antioxidant supplement for multiple sclerosis (MS) patients and many studies suggest correlations between a low VD serum…”
Get full text
Journal Article -
15
Guidance for use of neurofilament light chain as a cerebrospinal fluid and blood biomarker in multiple sclerosis management
Published in EBioMedicine (01-03-2024)“…Neurofilament light chain (NfL) is a long-awaited blood biomarker that can provide clinically useful information about prognosis and therapeutic efficacy in…”
Get full text
Journal Article -
16
Sex Differences under Vitamin D Supplementation in an Animal Model of Progressive Multiple Sclerosis
Published in Nutrients (01-02-2024)“…A central role for vitamin D (VD) in immune modulation has recently been recognized linking VD insufficiency to autoimmune disorders that commonly exhibit…”
Get full text
Journal Article -
17
Incidence of Developmental Venous Anomalies in Patients With Multiple Sclerosis: A 3 Tesla MRI Study
Published in Frontiers in neurology (29-03-2022)“…There is evidence of involvement of the venous system in multiple sclerosis (MS). If this bears also an association with the frequency and extent of…”
Get full text
Journal Article -
18
Digital optical tomography system for dynamic breast imaging
Published in Journal of Biomedical Optics (01-07-2011)“…Diffuse optical tomography has shown promising results as a tool for breast cancer screening and monitoring response to chemotherapy. Dynamic imaging of the…”
Get full text
Journal Article -
19
Evidence of polygenic regulation of the physiological presence of neurofilament light chain in human serum
Published in Frontiers in neurology (08-03-2023)“…The measurement of neurofilament light chain (NfL) in blood is a promising biomarker of neurological injury and disease. We investigated the genetic factors…”
Get full text
Journal Article -
20
Periventricular magnetisation transfer abnormalities in early multiple sclerosis
Published in NeuroImage clinical (01-01-2022)“…[Display omitted] •Periventricular-MTR gradients are present from the earliest stage of MS and become steeper in advanced disease.•Lower MTR in…”
Get full text
Journal Article