Search Results - "Khalil, Jawad S"

Coronin 1 Is Required for Integrin β2 Translocation in Platelets by Riley, David R J, Khalil, Jawad S, Pieters, Jean, Naseem, Khalid M, Rivero, Francisco

“…Remodeling of the actin cytoskeleton is one of the critical events that allows platelets to undergo morphological and functional changes in response to…”
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Biochemical and immunocytochemical characterization of coronins in platelets by Riley, David R. J., Khalil, Jawad S., Naseem, Khalid M., Rivero, Francisco

“…Rapid reorganization of the actin cytoskeleton in response to receptor-mediated signaling cascades allows platelets to transition from a discoid shape to a…”
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Protein Kinase A Regulates Platelet Phosphodiesterase 3A through an A-Kinase Anchoring Protein Dependent Manner by Khalil, Jawad S, Law, Robert, Raslan, Zaher, Cheah, Lih T, Hindle, Matthew S, Aburima, Ahmed A, Kearney, Mark T, Naseem, Khalid M

“…Platelet activation is critical for haemostasis, but if unregulated can lead to pathological thrombosis. Endogenous platelet inhibitory mechanisms are mediated…”
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Alterations in Platelet Alpha-Granule Secretion and Adhesion on Collagen under Flow in Mice Lacking the Atypical Rho GTPase RhoBTB3 by Berger, Martin, Lutz, David R J, Lutz, Julia, Khalil, Jawad S, Aburima, Ahmed, Naseem, Khalid M, Rivero, Francisco

“…Typical Rho GTPases, such as Rac1, Cdc42, and RhoA, act as molecular switches regulating various aspects of platelet cytoskeleton reorganization. The loss of…”
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The membrane-associated fraction of cyclase associate protein 1 translocates to the cytosol upon platelet stimulation by Joshi, Pooja, Riley, David R. J., Khalil, Jawad S., Xiong, Huajiang, Ji, Wei, Rivero, Francisco

“…Platelets undergo profound shape changes upon adhesion to damaged blood vessel walls that are mediated by reorganisation of the actin cytoskeleton in response…”
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Inhibition of Arginine Methylation Impairs Platelet Function by Marsden, Alistair James, Riley, David R. J, Barry, Antonia, Khalil, Jawad S, Guinn, Barbara-ann, Kemp, Neil T, Rivero, Francisco, Beltran-Alvarez, Pedro

“…Protein arginine methyltransferases (PRMTs) catalyze the transfer of methyl groups to arginine residues in proteins. PRMT inhibitors are novel, promising drugs…”
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