Search Results - "Khalil, E A G"

Efficacy of killed whole-parasite vaccines in the prevention of leishmaniasis—A meta-analysis by Noazin, Sassan, Khamesipour, Ali, Moulton, Lawrence H, Tanner, Marcel, Nasseri, Kiumarss, Modabber, Farrokh, Sharifi, Iraj, Khalil, E.A.G, Bernal, Ivan Dario Velez, Antunes, Carlos M.F, Smith, Peter G

“…Abstract Despite decades of investigation in countries on three continents, an efficacious vaccine against Leishmania infections has not been developed…”
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Immunological stimulation for the treatment of leishmaniasis: a modality worthy of serious consideration by Musa, Ahmed Mudawi, Noazin, Sassan, Khalil, E.A.G., Modabber, Farrokh

“…Instead of relying on drugs to reduce the parasite burden of leishmaniasis, and waiting for the effector immune response to develop in time to control the…”
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Blindness following visceral leishmaniasis: a neglected post-kala-azar complication by Khalil, E A G, Musa, A M, Younis, B M, Elfaki, M E E, Zijlstra, E E, Elhassan, A M

“…Visceral leishmaniasis (VL) is an important cause of morbidity and mortality that affects multiple organs. Post-kala-azar ocular involvement is a serious…”
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IFNG and IFNGR1 gene polymorphisms and susceptibility to post-kala-azar dermal leishmaniasis in Sudan by Salih, M A, Ibrahim, M E, Blackwell, J M, Miller, E N, Khalil, E A G, ElHassan, A M, Musa, A M, Mohamed, H S

“…Post-kala-azar dermal leishmanaisis (PKDL) in Sudan is associated with elevated interferon-gamma (IFN-gamma). To study interferon-gamma pathways in PKDL, we…”
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Treatment-Based Strategy for the Management of Post-Kala-Azar Dermal Leishmaniasis Patients in the Sudan by Musa, Ahmed Mudawi, Khalil, Eltahir Awad Gasim, Younis, B. M., Elfaki, Mona Elfaki Eltahir, Elamin, M. Y., Adam, A. O. A., Mohamed, H. A. A., Dafalla, M. M. M., Abuzaid, A. A., El Hassan, Ahmed Mohamed

“…Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that affects more than 50% of successfully treated visceral leishmaniasis (VL) patients in Sudan…”
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Leishmania donovani: Genetic diversity of isolates from Sudan characterized by PCR-based RAPD by Hamad, S.H., Khalil, E.A.G., Musa, A.M., Ibrahim, M.E., Younis, B.M., Elfaki, M.E.E., El-Hassan, A.M.

“…Drug unresponsiveness in patients with visceral leishmaniasis (VL) is a problem in many endemic areas . This study aimed to determine genetic diversity of…”
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Epidemiology and clinical manifestations of Leishmania donovani infection in two villages in an endemic area in eastern Sudan by Khalil, E. A. G., Zijlstra, E. E., Kager, P. A., El Hassan, A. M.

“…We conducted a longitudinal study in an endemic area for visceral leishmaniasis (VL) in eastern Sudan to compare the epidemiology and clinical spectrum of…”
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Diagnosis of tuberculous lymphadenitis by FNAC, microbiological methods and PCR: a comparative study by Aljafari, A. S., Khalil, E. A. G., Elsiddig, K. E., El Hag, I. A., Ibrahim, M. E., Elsafi, M. E. M. O., Hussein, A. M., Elkhidir, I. M., Sulaiman, G. S., Elhassan, A. M.

“…Despite its usefulness in the diagnosis of tuberculous lymphadenitis, fine needle aspiration cytology (FNAC) faces several limitations, and its sensitivity and…”
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The development of post‐kala‐azar dermal leishmaniasis (PKDL) is associated with acquisition of Leishmania reactivity by peripheral blood mononuclear cells (PBMC) by Gasim, S., Elhassan, A. M., Kharazmi, A., Khalil, E. A. G., Ismail, A., Theander, T. G.

“…PKDL develops in about 50% of Sudanese patients treated for visceral leishmaniasis (kala‐azar). Patients with kala‐azar were entered into this study and…”
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Subtotal laparoscopic cholecystectomy influences the rate of conversion in patients with difficult laparoscopic cholecystectomy: Case series by Abdelrahim, W.E, Elsiddig, Kamal E, Wahab, A.A, Saad, M, Saeed, H, Khalil, E.A.G

“…Abstract Objectives This study aimed to show that subtotal laparoscopic cholecystectomy (SLC) is a safe procedure that reduces the rate of conversion in…”
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Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan by Khalil, EAG, Hassan, AMEl, Zijlstra, EE, Mukhtar, MM, Ghalib, HW, Musa, Breyma, Ibrahim, ME, Kamil, Areeg A, Elsheikh, M, Babiker, A, Modabber, F

“…Visceral leishmaniasis is a major cause of morbidity and mortality in the Sudan. Drug treatment is expensive, and drug resistance is becoming increasingly…”
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Diagnosing visceral leishmaniasis with the recombinant K39 strip test: experience from the Sudan by Zijlstra, E. E., Nur, Y., Desjeux, P., Khalil, E. A. G., El‐Hassan, A. M., Groen, J.

“…We compared a strip test employing recombinant K39 (rK39) antigen and protein A/colloidal gold as read‐out agents with the rK39 ELISA for IgM and IgG…”
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Socio-cultural aspects of leprosy among the Masalit and Hawsa tribes in the Sudan by EL HASSAN, L. A, KHALIL, E. A. G, EL-HASSAN, A. M

“…Social and cultural factors influencing knowledge, attitudes and practices (KAP) towards leprosy in two communities in eastern Sudan were studied to determine…”
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Dichotomy of protective cellular immune responses to human visceral leishmaniasis by Khalil, E. A. G., Ayed, N. B., Musa, A. M., Ibrahim, M. E., Mukhtar, M. M., Zijlstra, E. E., Elhassan, I. M., Smith, P. G., Kieny, P. M., Ghalib, H. W., Zicker, F., Modabber, F., Elhassan, A. M.

“…Summary Healing/protective responses in human visceral leishmaniasis (VL) are associated  with  stimulation/production  of  Th1  cytokines,  such  as …”
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Genetic susceptibility to visceral leishmaniasis in The Sudan: linkage and association with IL4 and IFNGR1 by MOHAMED, H. S, IBRAHIM, M. E, MILLER, E. N, PEACOCK, C. S, KHALIL, E. A. G, CORDELL, H. J, HOWSON, J. M. M, EL HASSAN, A. M, BEREIR, R. E. H, BLACKWELL, J. M

“…Longitudinal studies in Sudan show ethnic differences in incidence and clinical phenotypes associated with Leishmania donovani. Immunologically, bias in type 1…”
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Post-kala-azar dermal leishmaniasis in the Sudan: clinical presentation and differential diagnosis by Zijlstra, E.E., Khalil, E.A.G., Kager, P.A., El-Hassan, A.M.

“…Post‐kala‐azar dermal leishmaniasis (PKDL) is a common complication following kala‐azar (visceral leishmaniasis). In a prospective study in a village in the…”
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High levels of plasma IL‐10 and expression of IL‐10 by keratinocytes during visceral leishmaniasis predict subsequent development of post‐kala‐azar dermal leishmaniasis by GASIM, S, ELHASSAN, A. M, KHALIL, E. A. G, ISMAIL, A, KADARU, A. M. Y, KHARAZMI, A, THEANDER, T. G

“…Some patients develop post‐kala‐azar dermal leishmaniasis (PKDL) after they have been treated for the systemic infection kala‐azar (visceral leishmaniasis). It…”
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rK39 enzyme-linked immunosorbent assay for diagnosis of Leishmania donovani infection by Zijlstra, E E, Daifalla, N S, Kager, P A, Khalil, E A, El-Hassan, A M, Reed, S G, Ghalib, H W

“…The rK39 enzyme-linked immunosorbent assay (ELISA) was compared with the direct agglutination test (DAT) for Leishmania donovani infection in the Sudan. rK39…”
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Alum-precipitated autoclaved Leishmania major plus bacille Calmette-Guérrin, a candidate vaccine for visceral leishmaniasis: safety, skin-delayed type hypersensitivity response and dose finding in healthy volunteers by Kamil, A.A., Khalil, E.A.G., Musa, A.M., Modabber, F., Mukhtar, M.M., Ibrahim, M.E., Zijlstra, E.E., Sacks, D., Smith, P.G., Zicker, F., El-Hassan, A.M.

“…In a previous efficacy study, autoclaved Leishmania major (ALM) + bacille Calmette—Guérrin (BCG) vaccine was shown to be safe, but not superior to BCG alone,…”
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Surrogate markers of subtle renal injury in patients with visceral leishmaniasis by Khalil, E. A. G., al-Hasan, Ahmad Muhammad, al-Faki, M. E. E., Yunus, B. M., Musa, Ahmad Madwi, al-Nujumi, N. A. A.

“…Sudanese Visceral Leishmaniasis (VL) is a disease of children that is characterized by fever, hepatosplenomegaly, lymphadenopathy, pancytopenia, and renal…”
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