Search Results - "Khalifa, Nasrin E."
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Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells
Published in Frontiers in pharmacology (28-06-2023)“…Among numerous triterpenoids of the Cucurbitaceae family, Cucurbitacin-B (Cur-B) is being explored for its pharmacological attributes. Reports from previous…”
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Corrigendum: Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells
Published in Frontiers in pharmacology (29-09-2023)“…[This corrects the article DOI: 10.3389/fphar.2023.1206981.]…”
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Synthesis and evaluation of pyridine-3-carboxamide analogs as effective agents against bacterial wilt in tomatoes
Published in Scientific reports (15-05-2024)“…This study focused on developing novel pyridine-3-carboxamide analogs to treat bacterial wilt in tomatoes caused by Ralstonia solanacearum . The analogs were…”
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A comprehensive assessment of phytochemicals from Phyla nodiflora (L.) Greene as a potential enzyme inhibitor, and their biological potential: An in-silico, in-vivo, and in-vitro approach
Published in Arabian journal of chemistry (01-11-2023)“…This work explored Phyla nodiflora (L.) Greene as a potential source of the bioactive medicinal agent. In this aspect, methanol (PN-M) and dichloromethane…”
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Green Synthesis of Zinc Oxide Nanoparticles Using Cymbopogon citratus Extract and Its Antibacterial Activity
Published in ACS omega (05-09-2023)“…Excessive use of antimicrobial medications including antibiotics has led to the emerging menace of antimicrobial resistance, which, as per the World Health…”
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Development and Optimization of Erythromycin Loaded Transethosomes Cinnamon Oil Based Emulgel for Antimicrobial Efficiency
Published in Gels (06-02-2023)“…Erythromycin (EM) is a macrolide antibiotic that is frequently used to treat skin bacterial infections. It has a short half-life (1-1.5 h), instability in…”
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Formulation and Evaluation of Amikacin Sulfate Loaded Dextran Nanoparticles against Human Pathogenic Bacteria
Published in Pharmaceutics (28-03-2023)“…Amikacin sulfate-loaded dextran sulfate sodium nanoparticles were formulated, lyophilized (LADNP), and then analyzed. The LADNP had a -20.9 ± 8.35 mV zeta…”
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Chemical Composition, Antibacterial Activity and In Vitro Anticancer Evaluation of Ochradenus baccatus Methanolic Extract
Published in Medicina (Kaunas, Lithuania) (10-03-2023)“…belongs to the family Resedaceae. It is widely spread in Saudi Arabia and other countries in Southwest Asia. is extensively used in traditional medicine as an…”
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Ginger Extract-Loaded Sesame Oil-Based Niosomal Emulgel: Quality by Design to Ameliorate Anti-Inflammatory Activity
Published in Gels (01-11-2022)“…Ginger, a natural plant belonging to the Zingeberaceae family, has been reported to have reasonable anti-inflammatory effects. The current study aimed to…”
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Metformin Therapy and Breast Cancer Incidence in the Ha'il Region
Published in Healthcare (Basel) (20-01-2023)“…Metformin is a drug used to treat patients with type 2 diabetes, especially those who suffer from obesity. It is also used in the treatment of women with…”
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The complex role of MEG3: An emerging long non-coding RNA in breast cancer
Published in Pathology, research and practice (01-11-2023)“…MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse biological processes, particularly breast cancer (BC) development. Within…”
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Deciphering the toxicological and computational assessment of Verbascum yemenese.: Integrating phytochemistry and bioinformatics tools
Published in Food and chemical toxicology (01-11-2024)“…This study explores the phytochemical composition and biological activities of Verbascum yemenense, a plant known for its medicinal properties. The plant…”
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Pyroptosis-related non-coding RNAs emerging players in atherosclerosis pathology
Published in Pathology, research and practice (01-03-2024)“…Globally, atherosclerosis a persistent inflammatory condition of the artery walls continues to be the primary cause of cardiovascular illness and death. The…”
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Repurposing of anisomycin and oleandomycin as a potential anti-(SARS-CoV-2) virus targeting key enzymes using virtual computational approaches
Published in Cellular and Molecular Biology (04-02-2022)“…Despite the accelerated emerging of vaccines, development against the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) drugs discovery is still in…”
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Integrative approach to the biochemical, and toxicological fingerprinting of Polygonum glabrum.: A computational and experimental synergy for a medicinal food plant
Published in Food bioscience (01-08-2024)“…In this work, the biological and chemical fingerprints of methanol and DCM extracts from an important Polygonum species (Polygonum glabrum) was investigated…”
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Chemical Composition, Antibacterial Activity and IIn Vitro/I Anticancer Evaluation of IOchradenus baccatus/I Methanolic Extract
Published in Medicina (Kaunas, Lithuania) (01-03-2023)“…Background and Objectives: Ochradenus baccatus belongs to the family Resedaceae. It is widely spread in Saudi Arabia and other countries in Southwest Asia. O…”
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ARTEMETHER LOADED ETHYLCELLULOSE NANOSUSPENSIONS: EFFECTS OF FORMULATION VARIABLES, PHYSICAL STABILITY AND DRUG RELEASE PROFILE
Published in International journal of pharmacy and pharmaceutical sciences (01-06-2017)“…Objective: The aim of this study was to explore the individual and joint effects of drug: ethylcellulose ratio, content of tween 80 and chloroform: water…”
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Lapachol and (α/β)-lapachone as inhibitors of SARS-CoV-2 Main Protease (Mpro) and hACE-2: ADME properties, docking and dynamic simulation approaches
Published in Pharmacognosy Magazine (01-07-2022)“…Background: Tabebuia impetiginosa is an important medicinal plant rich in lapachol, α-lapachone, and β-lapachone known to possess several biological…”
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