Search Results - "Khalidah Nasser"

Molecular modelling and dynamic simulations of sequestosome 1 (SQSTM1) missense mutations linked to Paget disease of bone by Shaik, Noor Ahmad, Nasser, Khalidah K., Alruwaili, Muteb Muidh, Alallasi, Sami Raja, Elango, Ramu, Banaganapalli, Babajan

“…The Paget disease (PDB; OMIM is 167250) is a chronic bone disease caused by pathogenic mutations in Sequestome1/p62 (SQSTM1) gene. This study has aimed to…”
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Identification of miRNA–mRNA–TFs regulatory network and crucial pathways involved in asthma through advanced systems biology approaches by Shaik, Noor Ahmad, Nasser, Khalidah, Mohammed, Arif, Mujalli, Abdulrahman, Obaid, Ahmad A, El-Harouni, Ashraf A, Elango, Ramu, Banaganapalli, Babajan

“…Asthma is a life-threatening and chronic inflammatory lung disease that is posing a true global health challenge. The genetic basis of the disease is fairly…”
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Exploring celiac disease candidate pathways by global gene expression profiling and gene network cluster analysis by Banaganapalli, Babajan, Mansour, Haifa, Mohammed, Arif, Alharthi, Arwa Mastoor, Aljuaid, Nada Mohammed, Nasser, Khalidah Khalid, Ahmad, Aftab, Saadah, Omar I., Al-Aama, Jumana Yousuf, Elango, Ramu, Shaik, Noor Ahmad

“…Celiac disease (CeD) is a gastrointestinal autoimmune disorder, whose specific molecular basis is not yet fully interpreted. Therefore, in this study, we…”
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Identification of a de novo LRP1 mutation in a Saudi family with Tetralogy of Fallot by Alrayes, Nuha, Mallah, Bayan A, Issa, Noha M., Banaganapalli, Babajan, Ahmad Shaik, Noor, Nasser, Khalidah K., Alshehri, Bandar Ali, Bhuiyan, Zahurul A., Bdier, Amnah Y., Al-Aama, Jumana Y.

“…[Display omitted] •A novel heterozygous de novo mutation in LRP1 was identified.•LRP1 variant was predicted to be pathogenic, resulting in potential changes in…”
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Molecular insights into the coding region mutations of low‐density lipoprotein receptor adaptor protein 1 (LDLRAP1) linked to familial hypercholesterolemia by Shaik, Noor A., Al‐Qahtani, Faten, Nasser, Khalidah, Jamil, Kaiser, Alrayes, Nuha Mohammad, Elango, Ramu, Awan, Zuhier Ahmed, Banaganapalli, Babajan

“…Background Familial hypercholesterolemia (FH) is a lipid disorder caused by pathogenic mutations in LDLRAP1 gene. The present study has aimed to deepen our…”
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Dissecting the Role of NF-κb Protein Family and Its Regulators in Rheumatoid Arthritis Using Weighted Gene Co-Expression Network by Sabir, Jamal S M, El Omri, Abdelfatteh, Banaganapalli, Babajan, Al-Shaeri, Majed A, Alkenani, Naser A, Sabir, Mumdooh J, Hajrah, Nahid H, Zrelli, Houda, Ciesla, Lukasz, Nasser, Khalidah K, Elango, Ramu, Shaik, Noor Ahmad, Khan, Muhummadh

“…Rheumatoid arthritis (RA) is a chronic synovial autoinflammatory disease that destructs the cartilage and bone, leading to disability. The functional…”
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Molecular differential analysis of uterine leiomyomas and leiomyosarcomas through weighted gene network and pathway tracing approaches by Sahly, Nora Naif, Banaganapalli, Babajan, Sahly, Ahmed N., Aligiraigri, Ali H., Nasser, Khalidah K., Shinawi, Thoraia, Mohammed, Arif, Alamri, Abdulhakeem S., Bondagji, Nabeel, Elango, Ramu, Shaik, Noor Ahmad

“…Uterine smooth muscular neoplastic growths like benign leiomyomas (UL) and metastatic leiomyosarcomas (ULMS) share similar clinical symptoms, radiological and…”
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Computational Protein Phenotype Characterization of IL10RA Mutations Causative to Early Onset Inflammatory Bowel Disease (IBD) by Al-Abbasi, Fahad A, Mohammed, Kaleemuddin, Sadath, Saida, Banaganapalli, Babajan, Nasser, Khalidah, Shaik, Noor A

“…The deleterious amino acid substitution mutations in IL-10 receptor alpha gene are most frequently reported in several autoimmune diseases including early…”
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Genotype-protein phenotype characterization of NOD2 and IL23R missense variants associated with inflammatory bowel disease: A paradigm from molecular modelling, dynamics, and docking simulations by Nasser, Khalidah Khalid, Shinawi, Thoraia

“…Inflammatory bowel disease (IBD) is a gastrointestinal disease with an underlying contribution of genetic, microbial, environment, immunity factors. The coding…”
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Novel MYO1D Missense Variant Identified Through Whole Exome Sequencing and Computational Biology Analysis Expands the Spectrum of Causal Genes of Laterality Defects by Alsafwani, Rabab Said, Nasser, Khalidah K., Shinawi, Thoraia, Banaganapalli, Babajan, ElSokary, Hanan Abdelhalim, Zaher, Zhaher F., Shaik, Noor Ahmad, Abdelmohsen, Gaser, Al-Aama, Jumana Yousuf, Shapiro, Adam J., O. Al-Radi, Osman, Elango, Ramu, Alahmadi, Turki

“…Laterality defects (LDs) or asymmetrically positioned organs are a group of rare developmental disorders caused by environmental and/or genetic factors…”
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Quality of life in children with Down syndrome and its association with parent and child demographic characteristics: Parent‐reported measures by Alrayes, Nuha, Issa, Noha M., Alghubayshi, Omar Y., Al‐Amaa, Jumana Y., Alsabban, Ashwaq Hassan, Al Shaer, Dalal Sameer, Alyoubi, Reem Abdullah, Nasser, Khalidah K., Alkhiary, Yaser M.

“…Background This study aims to explore the association between the quality of life (QoL) in children with Down syndrome (DS) and its relationship with…”
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SHH Signaling as a Key Player in Endometrial Cancer: Unveiling the Correlation with Good Prognosis, Low Proliferation, and Anti-Tumor Immune Milieu by Snijesh, V P, Krishnamurthy, Shivakumar, Bhardwaj, Vipul, Punya, K M, Niranjana Murthy, Ashitha S, Almutadares, Mahmoud, Habhab, Wisam Tahir, Nasser, Khalidah Khalid, Banaganapalli, Babajan, Shaik, Noor Ahmad, Albaqami, Walaa F

“…Endometrial Cancer (EC) is one of the most common gynecological malignancies. Despite its prevalence, molecular pathways, such as the Sonic Hedgehog (SHH)…”
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Bioinformatics insights into the genes and pathways on severe COVID-19 pathology in patients with comorbidities by Mujalli, Abdulrahman, Alghamdi, Kawthar Saad, Nasser, Khalidah Khalid, Al-Rayes, Nuha, Banaganapalli, Babajan, Shaik, Noor Ahmad, Elango, Ramu

“…Coronavirus disease (COVID-19) infection is known for its severe clinical pathogenesis among individuals with pre-existing comorbidities. However, the…”
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A comparative mRNA- and miRNA transcriptomics reveals novel molecular signatures associated with metastatic prostate cancers by Shinawi, Thoraia, Nasser, Khalidah Khalid, Moradi, Fatima Amanullah, Mujalli, Abdulrahman, Albaqami, Walaa F., Almukadi, Haifa S., Elango, Ramu, Shaik, Noor Ahmad, Banaganapalli, Babajan

“…Background: Prostate cancer (PC) is a fatally aggressive urogenital cancer killing millions of men, globally. Thus, this study aims to identify key miRNAs,…”
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Copy Number Variants in 30 Saudi Pediatric Patients with Neurodevelopmental Disorders: From Unknown Significance to Diagnosis by Alotibi, Raniah Saleem, Al Eissa, Mariam M, Aloraini, Taghrid, Nasser, Khalidah Khalid, Al Shammari, Muneera J, Alqahtani, Amerh S

“…Background: Structural variants (SVs), such as copy number variants (CNVs), insertions, deletions, inversions, and translocations, contribute significantly to…”
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Genome-Wide Association Study-Guided Exome Rare Variant Burden Analysis Identifies IL1R1 and CD3E as Potential Autoimmunity Risk Genes for Celiac Disease by Mansour, Haifa, Banaganapalli, Babajan, Nasser, Khalidah Khalid, Al-Aama, Jumana Yousuf, Shaik, Noor Ahmad, Saadah, Omar Ibrahim, Elango, Ramu

“…Celiac disease (CeD) is a multifactorial autoimmune enteropathy characterized by the overactivation of the immune system in response to dietary gluten. The…”
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Identification of a Rare Exon 19 Skipping Mutation in ALMS1 Gene in Alström Syndrome Patients From Two Unrelated Saudi Families by Saadah, Omar I, Banaganapalli, Babajan, Kamal, Naglaa M, Sahly, Ahmed N, Alsufyani, Hadeel A, Mohammed, Arif, Ahmad, Aftab, Nasser, Khalidah Khalid, Al-Aama, Jumana Y, Shaik, Noor Ahmad, Elango, Ramu

“…Alström syndrome (AS) is a very rare childhood disorder characterized by cardiomyopathy, progressive hearing loss and blindness. Inherited genetic variants of…”
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Molecular profiling of lamellar ichthyosis pathogenic missense mutations on the structural and stability aspects of TGM1 protein by Nasser, Khalidah Khalid, Banaganapalli, Babajan, Shinawi, Thoraia, Elango, Ramu, Shaik, Noor Ahmad

“…Lamellar ichthyosis (LI) is a rare inherited disease where affected infants present a extensive skin scaling characterized by hyperkeratosis. Inherited…”
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Identification of miRNA–mRNA–TFs regulatory network and crucial pathways involved in asthma through advanced systems biology approaches by Noor Ahmad Shaik, Khalidah Nasser, Arif Mohammed, Abdulrahman Mujalli, Ahmad A. Obaid, Ashraf A. El‐Harouni, Ramu Elango, Babajan Banaganapalli

“…Asthma is a life-threatening and chronic inflammatory lung disease that is posing a true global health challenge. The genetic basis of the disease is fairly…”
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Whole exome sequencing of a Saudi family and systems biology analysis identifies CPED1 as a putative causative gene to Celiac Disease by Bokhari, Hifaa A., Shaik, Noor Ahmad, Banaganapalli, Babajan, Nasser, Khalidah Khalid, Ageel, Hossain Ibrahim, Al Shamrani, Ali Saad, Rashidi, Omran M., Al Ghubayshi, Omar Yaseen, Shaik, Jilani, Ahmad, Aftab, Alrayes, Nuha Mohammad, Al-Aama, Jumana Yousuf, Elango, Ramu, Saadah, Omar Ibrahim

“…Celiac disease (CD) is a gastrointestinal disorder whose genetic basis is not fully understood. Therefore, we studied a Saudi family with two CD affected…”
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