Use of the Indigo CAT RX aspiration system during percutaneous coronary intervention

Background The use of the Indigo CAT RX Aspiration System (Penumbra Inc.) during percutaneous coronary intervention has received limited study. Methods We retrospectively examined the clinical, angiographic, and procedural characteristics, outcomes, and follow‐up of patients who underwent mechanical...

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Published in:	Catheterization and cardiovascular interventions Vol. 103; no. 5; pp. 695 - 702
Main Authors:	Peng, Sydney, Rempakos, Athanasios, Mastrodemos, Olga C., Rangan, Bavana V., Alexandrou, Michaella, Allana, Salman, Al‐Ogaili, Ahmed, Mutlu, Deniz, Karacsonyi, Judit, Bergstedt, Seth, Khalid, Muhmmad S., Stanberry, Larissa, Brilakis, Emmanouil S.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01-04-2024
Subjects:	Angioplasty aspiration thrombectomy Cerebral infarction Congestive heart failure Myocardial infarction Patients penumbra percutaneous coronary intervention Stroke Thrombolysis penumbra percutaneous coronary intervention aspiration thrombectomy
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Summary:	Background The use of the Indigo CAT RX Aspiration System (Penumbra Inc.) during percutaneous coronary intervention has received limited study. Methods We retrospectively examined the clinical, angiographic, and procedural characteristics, outcomes, and follow‐up of patients who underwent mechanical aspiration thrombectomy with the Indigo CAT RX system (Penumbra Inc.) at a large tertiary care hospital between January 2019 and April 2023. Results During the study period, 83 patients (85 lesions) underwent thrombectomy with the Indigo CAT RX. Mean patient age was 64.9 ± 14.48 years and 31.2% were women. The most common presentations were ST‐segment elevation myocardial infarction (MI) (66.2%) and non‐ST‐segment elevation MI (26.5%). A final thrombolysis in MI flow grade of 3 and final myocardial blush grade of 3 were achieved in 76% and 46% of the cases, respectively. Technical success was achieved in 88.9% of the cases that included Indigo CAT RX treatment only, compared with 57.1% of the cases that also included manual aspiration. There were no device‐related serious adverse events. At 30‐day postprocedure, the incidence of major adverse cardiac events (composite of cardiovascular death, recurrent MI, cardiogenic shock, new or worsening New York Heart Association Class IV heart failure, stroke) was 8.5%: 1.3% stroke (postprocedure, in‐hospital), 1.3% MI, 6.1% cardiac death, and 7.5% developed cardiogenic shock. Conclusions Use of the Indigo CAT RX system is associated with high technical success and acceptable risk of complications, including stroke.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1522-1946 1522-726X
DOI:	10.1002/ccd.30994