Determining the relationship between SARS-CoV-2 infection, dopamine, and COVID-19 complications

There is compelling evidence that aged, immunosuppressed, and chronically ill patients are a high-risk group for increased mortality upon infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study investigated the contribution of morbidities and related prescribe...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Taibah University Medical Sciences Vol. 15; no. 6; pp. 550 - 553
Main Authors: Khalefah, Muad M., Khalifah, Ayman M.
Format: Journal Article
Language:English
Published: Saudi Arabia Elsevier Ltd 01-12-2020
Taibah University
Elsevier
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There is compelling evidence that aged, immunosuppressed, and chronically ill patients are a high-risk group for increased mortality upon infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study investigated the contribution of morbidities and related prescribed medications to COVID-19 associated mortality. Based on the various recently reported clinical scenarios a theoretical framework was designed to shed light on the mode of infection of the central nervous system by SARS-CoV-2 and possible management options. Dopamine-release mechanisms in the central nervous system may play a major role in the entry and propagation of coronaviruses. This study emphasizes the need for a thorough and urgent investigation of the dopamine-release pathways in the central nervous system. These efforts will help find a definitive cure for the pandemic coronavirus disease (COVID-19).
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1658-3612
1658-3612
DOI:10.1016/j.jtumed.2020.10.006