Search Results - "Khaleel I. Assaf"

The Chaotropic Effect as an Assembly Motif in Chemistry by Assaf, Khaleel I., Nau, Werner M.

“…Following up on scattered reports on interactions of conventional chaotropic ions (for example, I−, SCN−, ClO4−) with macrocyclic host molecules, biomolecules,…”
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Applications of Cucurbiturils in Medicinal Chemistry and Chemical Biology by Das, Debapratim, Assaf, Khaleel I., Nau, Werner M.

“…The supramolecular chemistry of cucurbit[ n ]urils (CB n ) has been rapidly developing to encompass diverse medicinal applications, including drug formulation…”
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Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications by Lazar, Alexandra I, Biedermann, Frank, Mustafina, Kamila R, Assaf, Khaleel I, Hennig, Andreas, Nau, Werner M

“…Cucurbit­[n]­urils (CBn, n = 7, 8) serve as artificial receptors for steroids (21 tested), including the hormones testosterone and estradiol as well as…”
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High-affinity host-guest chemistry of large-ring cyclodextrins by Assaf, Khaleel I, Gabel, Detlef, Zimmermann, Wolfgang, Nau, Werner M

“…The host-guest chemistry of large-ring cyclodextrins (LRCDs) has been largely unexplored due to the lack of suitable guest molecules that bind with significant…”
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High-Affinity Binding of Metallacarborane Cobalt Bis(dicarbollide) Anions to Cyclodextrins and Application to Membrane Translocation by Assaf, Khaleel I, Begaj, Barbara, Frank, Angelina, Nilam, Mohamed, Mougharbel, Ali S, Kortz, Ulrich, Nekvinda, Jan, Grüner, Bohumír, Gabel, Detlef, Nau, Werner M

“…Metallacarboranes are a class of inorganic boron clusters that have recently been recognized as biologically active compounds. Herein, we report on the…”
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Dodecaborate-Functionalized Anchor Dyes for Cyclodextrin-Based Indicator Displacement Applications by Assaf, Khaleel I, Suckova, Olga, Al Danaf, Nader, von Glasenapp, Victoria, Gabel, Detlef, Nau, Werner M

“…A new type of water-soluble anchor dyes, that is, dyes which carry an auxiliary unit for strong binding to macrocyclic host molecules, has been synthesized. It…”
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HYDROPHOBE Challenge: A Joint Experimental and Computational Study on the Host–Guest Binding of Hydrocarbons to Cucurbiturils, Allowing Explicit Evaluation of Guest Hydration Free-Energy Contributions by Assaf, Khaleel I, Florea, Mara, Antony, Jens, Henriksen, Niel M, Yin, Jian, Hansen, Andreas, Qu, Zheng-wang, Sure, Rebecca, Klapstein, Dieter, Gilson, Michael K, Grimme, Stefan, Nau, Werner M

“…The host–guest complexation of hydrocarbons (22 guest molecules) with cucurbit[7]­uril was investigated in aqueous solution using the indicator displacement…”
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Selective Detection of Nitroexplosives Using Molecular Recognition within Self-Assembled Plasmonic Nanojunctions by Chio, Weng-I Katherine, Peveler, William J, Assaf, Khaleel I, Moorthy, Suresh, Nau, Werner M, Parkin, Ivan P, Olivo, Malini, Lee, Tung-Chun

“…We demonstrate that the reproducibility of sensors for nitroaromatics based on surface-enhanced Raman spectroscopy (SERS) can be significantly improved via a…”
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Cinnamaldehyde-cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity by Al Tbakhi, Bayan, Nsairat, Hamdi, Alshaer, Walhan, Al-Kadash, Abdulfattah, Helal, Wissam, Alrawashdeh, Lubna, Day, Anthony, Assaf, Khaleel I, Hassouneh, Rola, Odeh, Fadwa, Al Bawab, Abeer

“…This study aimed to clarify the physico-chemical properties of cucurbit[7]uril (CB[7]) and cinnamaldehyde (Cinn) inclusion complexes (CB[7]-Cinn) and their…”
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Precise supramolecular control of surface coverage densities on polymer micro- and nanoparticles by Zhang, Shuai, Domínguez, Zoe, Assaf, Khaleel I, Nilam, Mohamed, Thiele, Thomas, Pischel, Uwe, Schedler, Uwe, Nau, Werner M, Hennig, Andreas

“…We report herein the controlled surface functionalization of micro- and nanoparticles by supramolecular host-guest interactions. Our idea is to exploit the…”
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Investigation of isomeric flavanol structures in black tea thearubigins using ultraperformance liquid chromatography coupled to hybrid quadrupole/ion mobility/time of flight mass spectrometry by Yassin, Ghada H., Grun, Christian, Koek, Jean H., Assaf, Khaleel I., Kuhnert, Nikolai

“…Ultra performance liquid chromatography (UPLC) when coupled to ion mobility (IMS)/orthogonal acceleration time of flight mass spectrometry is a suitable…”
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Binary and Ternary Complexes of Cucurbit[8]uril with Tryptophan, Phenylalanine, and Tyrosine: A Computational Study by El-Barghouthi, Musa I, Bodoor, Khaled, Abuhasan, Osama M, Assaf, Khaleel I, Al Hourani, Baker Jawabrah, Rawashdeh, Abdel Monem M

“…Selective binding of amino acids, peptides, and proteins by synthetic molecules and elucidation of the geometry and dynamics of the resulting complexes and…”
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Biomaterials for CO2 Harvesting: From Regulatory Functions to Wet Scrubbing Applications by Assaf, Khaleel I, Qaroush, Abdussalam K, Mustafa, Farah M, Alsoubani, Fatima, Pehl, Thomas M, Troll, Carsten, Rieger, Bernhard, Eftaiha, Ala’a F

“…A new series of 2-aminoethyl-benzene-based biomaterials, namely, dopamine (DOP), tyramine (TYR), phenylethylamine (PEA), and epinephrine (EPN), dissolved in…”
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Synthesis, Crystal Structure, Spectroscopic and Computational Studies of 2-{1-[2-(1,3-Dimethyl-4-nitro-1H-pyrazol-5-yl)hydrazono]ethyl}pyridine by A. Abu-Safieh, Kayed, S. Abushamleh, Ahmad, A. Khanfar, Monther, I. Assaf, Khaleel, A. Salameh, Bader, J. Alwahsh, Nisreen

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Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to [gamma]-Cyclodextrin by Assaf, Khaleel I, Ural, Merve S, Pan, Fangfang, Georgiev, Tony, Simova, Svetlana, Rissanen, Kari, Gabel, Detlef, Nau, Werner M

“…Dodecaborate anions of the type B12X122- and B12X11Y2- (X=H, Cl, Br, I and Y=OH, SH, NH3+, NR3+) form strong (Ka up to 106Lmol-1, for B12Br122-) inclusion…”
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Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin by Assaf, Khaleel I., Ural, Merve S., Pan, Fangfang, Georgiev, Tony, Simova, Svetlana, Rissanen, Kari, Gabel, Detlef, Nau, Werner M.

“…Dodecaborate anions of the type B12X122− and B12X11Y2− (X=H, Cl, Br, I and Y=OH, SH, NH3+, NR3+) form strong (Ka up to 106 L mol−1, for B12Br122−) inclusion…”
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Boron clusters as broadband membrane carriers by Barba-Bon, Andrea, Salluce, Giulia, Lostalé-Seijo, Irene, Assaf, Khaleel. I., Hennig, Andreas, Montenegro, Javier, Nau, Werner M.

“…The membrane translocation of hydrophilic substances constitutes a challenge for their application as therapeutic compounds and labelling probes 1 – 4 . To…”
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Dispersion Interactions in Condensed Phases and inside Molecular Containers by Assaf, Khaleel I, Nau, Werner M

“…ConspectusThe past decade has seen significant progress in the understanding and appreciation of the importance of London dispersion interactions (LDIs) in…”
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A Fluorescein-Substituted Perbrominated Dodecaborate Cluster as an Anchor Dye for Large Macrocyclic Hosts and Its Application in Indicator Displacement Assays by Zhang, Jinling, Gabel, Detlef, Assaf, Khaleel I., Nau, Werner M.

“…Perhalogenated boron clusters derived from B12Br12 2–, a superchaotropic dianion with a globular icosahedral shape, serve as inorganic cavity binders for…”
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Deep Inside Cucurbiturils: Physical Properties and Volumes of their Inner Cavity Determine the Hydrophobic Driving Force for Host-Guest Complexation by Nau, Werner M., Florea, Mara, Assaf, Khaleel I.

“…Cucurbit[n]urils (CBn) bind guest molecules through a combination of electrostatic interactions with the carbonyl rims and hydrophobic interactions with the…”
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