Search Results - "Khalansky, A S"
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Morphological and molecular-biological features of glioblastoma progression in tolerant and susceptible to hypoxia Wistar rats
Published in Scientific reports (04-08-2023)“…Hypoxia is a major pathogenetic factor in many cancers. Individual resistance to suboptimal oxygen availability is subject to broad variation and its possible…”
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Comparative Morphological and Molecular Genetic Characteristics of Cell and Tissue Strains of Experimental Rat Glioma 10-17-2 (Astrid-17)
Published in Bulletin of experimental biology and medicine (01-05-2024)“…In order to obtain models of gliomas of varying degrees of malignancy, we performed morphological and molecular genetic study of a tissue strain of glioma…”
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The Effect of Therapy Regimen on Antitumor Efficacy of the Nanosomal Doxorubicin against Rat Glioblastoma 101.8
Published in Bulletin of experimental biology and medicine (01-03-2024)“…One of the key problems of glioblastoma treatment is the low effectiveness of chemotherapeutic drugs. Incorporation of doxorubicin into PLGA nanoparticles…”
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Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma
Published in Toxicology letters (25-01-2002)“…Polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles (NP) were shown to enable the transport of a number of drugs including the anti-tumour antibiotic…”
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5
Terahertz dielectric spectroscopy and solid immersion microscopy of ex vivo glioma model 101.8: brain tissue heterogeneity
Published in Biomedical optics express (01-08-2021)“…Terahertz (THz) technology holds strong potential for the intraoperative label-free diagnosis of brain gliomas, aimed at ensuring their gross-total resection…”
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Combination of nanosomal form of doxorubicin, interferon alpha, and nitroglycerin in the threatment of 101.8 glioblastoma in Wistar rats
Published in Антибиотики и Химиотерапия (02-01-2022)“…The search for effective approaches to the treatment of patients with glioblastoma is one of the difficult tasks of neurooncology; standard methods of therapy…”
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7
Multiplication and Isolation of Hepatitis C Virus in the NGUK-1 Rat Neurinoma Neural Cells
Published in Bulletin of experimental biology and medicine (01-12-2009)“…Hepatitis C virus (HCV) strains were isolated from human sera in vitro. NGUK-1 rat neurinoma neural cells [1] were selected as the experimental model of HCV…”
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Nitric oxide donor nitrosorbide potentiates the antitumor effect of doxorubicin against experimental glioblastoma
Published in Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko (2022)“…Doxorubicin is a well-known antitumor drug that is not employed for chemotherapy of brain tumors. Indeed, doxorubicin does not penetrate across the blood-brain…”
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Chemotherapy of glioblastoma in rats using doxorubicin‐loaded nanoparticles
Published in International journal of cancer (01-05-2004)“…Glioblastomas belong to the most aggressive human cancers with short survival times. Due to the blood‐brain barrier, they are mostly inaccessible to…”
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10
Efficient systemic therapy of rat glioblastoma by nanoparticle-bound doxorubicin is due to antiangiogenic effects
Published in Clinical neuropathology (01-05-2009)“…The objective of this study was to investigate the therapeutic effects of doxorubicin bound to polysorbate-coated nanoparticles that had previously been shown…”
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Biodistribution of polysorbate 80-coated doxorubicin-loaded [14C]-poly(butyl cyanoacrylate) nanoparticles after intravenous administration to glioblastoma-bearing rats
Published in Journal of drug targeting (01-01-2006)“…It was recently shown that doxorubicin (DOX) bound to polysorbate-coated nanoparticles (NP) crossed the intact blood-brain barrier (BBB), and thus reached…”
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Neurochordins of higher vertebrates: similarities in P-epitope-bearing polypeptide composition and a study of P-epitope expression in cultured neural tissue cells
Published in Neuroscience letters (09-12-1991)“…Neurochordins are a family of high Mr P-epitope-bearing neural tissue glycoproteins. Comparison of SDS-agarose electrophoretic patterns of extracts from human,…”
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Potentiating Effect of Nitric Oxide Donor on Antitumor Activity of Doxorubicin in Glioblastoma-Bearing Rats
Published in Антибиотики и Химиотерапия (01-05-2020)“…The objective of the study was to investigate the influence of the NO donor nitroglycerin (NG) on the antitumour effect of doxorubicin (Dox) in rats with the…”
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14
Specific binding of [3H]diazepam in mouse glioblastoma: the influence of clonazepam and Ro 5-4864 on [3H]diazepam binding
Published in Neuroscience letters (21-12-1984)“…The reversible specific binding of [3H]diazepam was observed by a radioligand method in homogenates of cultured cells of mouse glioblastoma. It was…”
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