Search Results - "Khalaf, Noura El Adle"
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Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling
Published in Biomedicine & pharmacotherapy (01-02-2023)“…Hepatocellular carcinoma (HCC) is the third foremost cause of cancer-related deaths. HCC has a very bad prognosis because it is asymptomatic in the early…”
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Diacetylrhein, an anthraquinone antiarthritic agent, suppresses dextran sodium sulfate-induced inflammation in rats: A possible mechanism for a protective effect against ulcerative colitis
Published in Biomedicine & pharmacotherapy (01-10-2022)“…Ulcerative colitis (UC) is a chronic inflammatory life-threatening and premalignant disorder with no cure that even might end up with surgical removal of a…”
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Pimitespib, an HSP90 inhibitor, augments nifuroxazide-induced disruption in the IL-6/STAT3/HIF-1α autocrine loop in rats with bleomycin-challenged lungs: Evolutionary perspective in managing pulmonary fibrosis
Published in Biomedicine & pharmacotherapy (01-09-2022)“…Idiopathic pulmonary fibrosis is a fatal lung disorder in which the etiology and pathogenesis are still unobvious. Effective treatments are urgently needed…”
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Nicardipine-chitosan nanoparticles alleviate thioacetamide-induced acute liver injury by targeting NFκB/NLRP3/IL-1β signaling in rats: Unraveling new roles beyond calcium channel blocking
Published in International immunopharmacology (15-11-2024)“…[Display omitted] •NCD-ChNPs prolong NCD circulation and residence time.•NCD-ChNPs enhance hepatic localization of NCD.•NCD-ChNps show pH-sensitive release,…”
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Clopidogrel combats neuroinflammation and enhances learning behavior and memory in a rat model of Alzheimer's disease
Published in Pharmacology, biochemistry and behavior (01-08-2020)“…Alzheimer's disease (AD) is a progressive neurodegenerative disease. Multiple molecular mechanisms have been employed in its pathogenesis such as Amyloid β…”
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