Search Results - "Khal, J."

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    Increased expression of proteasome subunits in skeletal muscle of cancer patients with weight loss by Khal, J., Hine, A.V., Fearon, K.C.H., Dejong, C.H.C., Tisdale, M.J.

    “…Atrophy of skeletal muscle is common in patients with cancer and results in increased morbidity and mortality. In order to design effective therapy the…”
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    Journal Article
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    Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia by KHAL, J, WYKE, S. M, RUSSELL, S. T, HINE, A. V, TISDALE, M. J

    Published in British journal of cancer (03-10-2005)
    “…Muscle protein degradation is thought to play a major role in muscle atrophy in cancer cachexia. To investigate the importance of the ubiquitin-proteasome…”
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  4. 4

    Induction of protein catabolism in myotubes by 15( )-hydroxyeicosatetraenoic acid through increased expression of the ubiquitin-proteasome pathway by WHITEHOUSE, A. S, KHAL, J, TISDALE, M. J

    Published in British journal of cancer (18-08-2003)
    “…The potential role of 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE) as an intracellular signal for increased protein catabolism and induction of the…”
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    Downregulation of muscle protein degradation in sepsis by eicosapentaenoic acid (EPA) by Khal, Jwan, Tisdale, Michael J.

    “…Eicosapentaenoic acid (EPA) has been shown to attenuate muscle atrophy in cancer, starvation and hyperthermia by downregulating the increased expression of the…”
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    Minimally invasive prostate cancer detection test using FISH probes by Tinawi-Aljundi R, Knuth ST, Gildea M, Khal J, Hafron J, Kernen K, Di Loreto R, Aurich-Costa J

    Published in Research and reports in urology (01-07-2016)
    “…Rima Tinawi-Aljundi,1 Shannon T Knuth,2 Michael Gildea,2 Joshua Khal,2 Jason Hafron,1 Kenneth Kernen,1 Robert Di Loreto,1 Joan Aurich-Costa2 1Pathology and…”
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    Downregulation of ubiquitin-dependent protein degradation in murine myotubes during hyperthermia by eicosapentaenoic acid by Smith, Helen J., Khal, Jwan, Tisdale, Michael J.

    “…Muscle atrophy in a number of acute wasting conditions is associated with an increased activity and expression of the ubiquitin–proteasome proteolytic pathway…”
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    Signalling pathways in the induction of proteasome expression by proteolysis-inducing factor in murine myotubes by Wyke, Stacey M., Khal, Jwan, Tisdale, Michael J.

    Published in Cellular signalling (2005)
    “…The mechanism by which the tumour product proteolysis-inducing factor (PIF) induced increased expression of the ubiquitin–proteasome proteolytic pathway was…”
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