Search Results - "Khajuria, Rajiv K"
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Tobacco smoke condensate-induced senescence in endothelial cells was ameliorated by colchicine treatment via suppression of NF-κB and MAPKs P38 and ERK pathways activation
Published in Cell communication and signaling (03-04-2024)“…Smoking is the major cause of cardiovascular diseases and cancer. It induces oxidative stress, leading to DNA damage and cellular senescence. Senescent cells…”
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Patient-Derived Tumor Organoids for Guidance of Personalized Drug Therapies in Recurrent Glioblastoma
Published in International journal of molecular sciences (12-06-2022)“…An obstacle to effective uniform treatment of glioblastoma, especially at recurrence, is genetic and cellular intertumoral heterogeneity. Hence, personalized…”
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Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
Published in Cell (22-03-2018)“…Blood cell formation is classically thought to occur through a hierarchical differentiation process, although recent studies have shown that lineage commitment…”
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DTI fiber tractography of cerebro-cerebellar pathways and clinical evaluation of ataxia in childhood posterior fossa tumor survivors
Published in Journal of neuro-oncology (2017)“…Pediatric posterior fossa (PF) tumor survivors experience long-term motor deficits. Specific cerebrocerebellar connections may be involved in incidence and…”
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Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease
Published in Nature communications (07-05-2020)“…Graft versus host disease (GvHD) is the main complication of allogeneic hematopoietic stem cell transplantation (HSCT). Here we report studies of a patient…”
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Emerging cellular and gene therapies for congenital anemias
Published in American journal of medical genetics. Part C, Seminars in medical genetics (01-12-2016)“…Congenital anemias comprise a group of blood disorders characterized by a reduction in the number of peripherally circulating erythrocytes. Various genetic…”
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Tobacco smoke condensate-induced senescence in endothelial cells was ameliorated by colchicine treatment via suppression of NF-κB and MAPKs P38 and ERK pathways activation
Published in Cell communication and signaling (03-04-2024)“…Smoking is the major cause of cardiovascular diseases and cancer. It induces oxidative stress, leading to DNA damage and cellular senescence. Senescent cells…”
Get full text
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Identification of Somatic Mutations in Expanded T Cell Clones of Patients with Chronic Graft-Versus-Host Disease (GVHD)
Published in Blood (08-12-2017)“…Background: GVHD is the main complication in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Chronic GVHD (cGVHD) develops in 60-80 % of…”
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Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis
Published in American journal of human genetics (04-08-2016)“…Circulating blood cell counts and indices are important indicators of hematopoietic function and a number of clinical parameters, such as blood oxygen-carrying…”
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