Search Results - "Khairuddin, Sharafuddin"

Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives by Strekalova, Tatyana, Liu, Yanzhi, Kiselev, Daniel, Khairuddin, Sharafuddin, Chiu, Jennifer Lok Yu, Lam, Justin, Chan, Ying-Shing, Pavlov, Dmitrii, Proshin, Andrey, Lesch, Klaus-Peter, Anthony, Daniel C., Lim, Lee Wei

“…Rationale The chronic mild stress (CMS) paradigm was first described almost 40 years ago and has become a widely used model in the search for antidepressant…”
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Dysregulation of the orexinergic system: A potential neuropeptide target in depression by Khairuddin, Sharafuddin, Aquili, Luca, Heng, Boon Chin, Hoo, Tze Lok Cecil, Wong, Kah Hui, Lim, Lee Wei

“…•Dysregulation of orexinergic function is implicated in the pathophysiology of•depression.•Hypo- and hyperactivity of orexin induce pro- or antidepressant-like…”
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Hericium erinaceus potentially rescues behavioural motor deficits through ERK-CREB-PSD95 neuroprotective mechanisms in rat model of 3-acetylpyridine-induced cerebellar ataxia by Chong, Pit Shan, Khairuddin, Sharafuddin, Tse, Anna Chung Kwan, Hiew, Lih Fhung, Lau, Chun Lok, Tipoe, George Lim, Fung, Man-Lung, Wong, Kah Hui, Lim, Lee Wei

“…Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although several studies have demonstrated the neuroprotective effects of…”
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Hericium erinaceus Promotes Anti-Inflammatory Effects and Regulation of Metabolites in an Animal Model of Cerebellar Ataxia by Chau, Sze Chun, Chong, Pit Shan, Jin, Hongkai, Tsui, Ka Chun, Khairuddin, Sharafuddin, Tse, Anna Chung Kwan, Lew, Sze Yuen, Tipoe, George Lim, Lee, Chi Wai, Fung, Man-Lung, Wong, Kah Hui, Lim, Lee Wei

“…Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although previous study demonstrated the neuroprotective effects of ( ), the…”
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Antidepressant-like effects of transcorneal electrical stimulation in rat models by Yu, Wing Shan, Tse, Anna Chung-Kwan, Guan, Li, Chiu, Jennifer Lok Yu, Tan, Shawn Zheng Kai, Khairuddin, Sharafuddin, Agadagba, Stephen Kugbere, Lo, Amy Cheuk Yin, Fung, Man-Lung, Chan, Ying-Shing, Chan, Leanne Lai Hang, Lim, Lee Wei

“…Given that visual impairment is bi-directionally associated with depression, we examined whether transcorneal electrical stimulation (TES), a non-invasive…”
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Prelimbic Cortical Stimulation Induces Antidepressant-like Responses through Dopaminergic-Dependent and -Independent Mechanisms by Khairuddin, Sharafuddin, Lim, Wei Ling, Aquili, Luca, Tsui, Ka Chun, Tse, Anna Chung-Kwan, Jayalath, Shehani, Varma, Ruhani, Sharp, Trevor, Benazzouz, Abdelhamid, Steinbusch, Harry, Blokland, Arjan, Temel, Yasin, Lim, Lee Wei

“…High-frequency stimulation (HFS) is a promising therapy for patients with depression. However, the mechanisms underlying the HFS-induced antidepressant-like…”
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A Decade of Progress in Deep Brain Stimulation of the Subcallosal Cingulate for the Treatment of Depression by Khairuddin, Sharafuddin, Ngo, Fung Yin, Lim, Wei Ling, Aquili, Luca, Khan, Naveed Ahmed, Fung, Man-Lung, Chan, Ying-Shing, Temel, Yasin, Lim, Lee Wei

“…Major depression contributes significantly to the global disability burden. Since the first clinical study of deep brain stimulation (DBS), over 446 patients…”
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Sex-Specific ADHD-like Behaviour, Altered Metabolic Functions, and Altered EEG Activity in Sialyltransferase ST3GAL5-Deficient Mice by Strekalova, Tatyana, Veniaminova, Ekaterina, Svirin, Evgeniy, Kopeikina, Ekaterina, Veremeyko, Tatyana, Yung, Amanda W Y, Proshin, Andrey, Tan, Shawn Zheng Kai, Khairuddin, Sharafuddin, Lim, Lee Wei, Lesch, Klaus-Peter, Walitza, Susanne, Anthony, Daniel C, Ponomarev, Eugene D

“…A deficiency in GM3-derived gangliosides, resulting from a lack of lactosylceramide-alpha-2,3-sialyltransferase (ST3GAL5), leads to severe neuropathology,…”
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Behavioural responses of anxiety in aversive and non-aversive conditions between young and aged Sprague-Dawley rats by Hiew, Lih Fhung, Khairuddin, Sharafuddin, Aquili, Luca, Koh, Junhao, Fung, Man-Lung, Lim, Wei Ling, Lim, Lee Wei

“…•Aged and young animals display different severity of anxiety when tested in behavioural assays modified with aversive & non-aversive conditions.•Aged animals…”
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IHericium erinaceus/I Promotes Anti-Inflammatory Effects and Regulation of Metabolites in an Animal Model of Cerebellar Ataxia by Chau, Sze Chun, Chong, Pit Shan, Jin, Hongkai, Tsui, Ka Chun, Khairuddin, Sharafuddin, Tse, Anna Chung Kwan, Lew, Sze Yuen, Tipoe, George Lim, Lee, Chi Wai, Fung, Man-Lung, Wong, Kah Hui, Lim, Lee Wei

“…Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although previous study demonstrated the neuroprotective effects of Hericium…”
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Tetratricopeptide repeat domain 9A modulates anxiety-like behavior in female mice by Lim, Lee Wei, Shrestha, Smeeta, Or, Yu Zuan, Tan, Shawn Zheng Kai, Chung, Hwa Hwa, Sun, Yang, Lim, Chew Leng, Khairuddin, Sharafuddin, Lufkin, Thomas, Lin, Valerie Chun Ling

“…Tetratricopeptide repeat domain 9A (TTC9A) expression is abundantly expressed in the brain. Previous studies in TTC9A knockout (TTC9A −/− ) mice have indicated…”
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Electrical stimulation rescues dopaminergic degeneration in dorsal raphe nucleus and enhanced hippocampal neurogenesis of vulnerable depressive rats by Sharafuddin, Khairuddin, Wei Ling, Lim, William Wai Lun, Fung, Yasin, Temel, Lee Wei, Lim

“…Abstract only…”
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