Cocaine-Related Aortic Dissection: what do we know?

Cocaine-Related Aortic Dissection: what do we know?

Cocaine use is known to be associated with an increased risk for vascular diseases. It is likely to trigger or increase the risk for an aortic dissection. We conducted an analysis of 45 cases of cocaine-related aortic dissection to further characterize the clinical features and outcomes of this pati...

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Bibliographic Details
Published in:Revista brasileira de cirurgia cardiovascular Vol. 35; no. 5; pp. 764 - 769
Main Authors: Greve, Dustin, Funke, Joana, Khairi, Tiam, Montagner, Matteo, Starck, Christoph, Falk, Volkmar, Sá, Michel Pompeu B O, Kurz, Stephan D
Format: Journal Article
Language:English
Published: Brazil Sociedade Brasileira de Cirurgia Cardiovascular 01-01-2020
Subjects:
Acute coronary syndromes
Aneurysm
Aneurysm, Dissecting - chemically induced
Aortic Aneurysm, Thoracic
Aortic dissection
CARDIAC & CARDIOVASCULAR SYSTEMS
Case reports
Cocaine
Cocaine - adverse effects
Cocaine-Related Disorders
Cocaine-Related Disorders - complications
Coronary vessels
Dissection
Heart surgery
Hospital Mortality
Humans
Hypertension
Male
Mortality
Nervous system
Patients
Population
Retrospective Studies
Review
Smoking
SURGERY
Treatment Outcome
Vascular Surgical Procedures
Dissection. Cocaine-Related Disorders. Aortic Aneurysm
Thoracic. Vascular Surgical Procedures. Treatment Outcome
Aneurysm
Vascular Surgical Procedures
Treatment Outcome
Cocaine-Related Disorders
Aortic Aneurysm, Thoracic
Dissection
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Summary:Cocaine use is known to be associated with an increased risk for vascular diseases. It is likely to trigger or increase the risk for an aortic dissection. We conducted an analysis of 45 cases of cocaine-related aortic dissection to further characterize the clinical features and outcomes of this patient cohort. Our study cohort of 45 patients consisted of 11 cases from our institutional database and 34 published case reports. The observed cases of acute aortic dissection related to cocaine use showed a high proportion of young (41.3±8.67 years) and male (88.9%) patients. Most of the cases (75%) were classified as Stanford type A. Also, in 75% of the cases, cocaine use was prevalent for more than one year. Median time from last cocaine use to onset of symptoms was one hour. In-hospital mortality was 21.4%, while additional 11.9% of the cases died before arriving at the hospital. Acute aortic dissection related to cocaine use occurs in predominantly young male patients and has a dismal outcome when compared to all comer series.
ISSN:1678-9741
0102-7638
1678-9741
DOI:10.21470/1678-9741-2020-0333