Search Results - "Khadrawy, Yasser"
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Antidepressant effects of curcumin-coated iron oxide nanoparticles in a rat model of depression
Published in European journal of pharmacology (05-10-2021)“…The antidepressant effect of curcumin-coated iron oxide nanoparticles (Cur-IONPs) was investigated in the current study using depression rat model induced by…”
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2
Electrophysiological and neurochemical evaluation of the adverse effects of REM sleep deprivation and epileptic seizures on rat's brain
Published in Life sciences (1973) (15-05-2021)“…The current study aims to investigate the impact of paradoxical (REM) sleep deprivation and/or epileptic seizures on rat's cortical brain tissues. Animals were…”
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Dose-dependent biological toxicity of green synthesized silver nanoparticles in rat’s brain
Published in Scientific reports (31-12-2022)“…Metal nanoparticles, in general, and silver nanoparticles (AgNPs), in particular, have been the focus of numerous studies over the last two decades. Recently,…”
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4
Protective effect of curcumin nanoparticles against cardiotoxicity induced by doxorubicin in rat
Published in Biochimica et biophysica acta. Molecular basis of disease (01-05-2020)“…The present study designed to investigate the protective effect of curcumin nanoparticles (CUR-NPs) on the cardiotoxicity induced by doxorubicin. Rats were…”
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Protective effect of nanocurcumin against neurotoxicity induced by doxorubicin in rat’s brain
Published in Neurotoxicology (Park Forest South) (01-07-2021)“…[Display omitted] •Doxorubicin increased cortical dopamine.•Doxorubicin reduced the activities of acetylcholinesterase and monoamine oxidase.•Doxorubicin…”
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Antidepressant and antioxidant effects of transcranial irradiation with 830-nm low-power laser in an animal model of depression
Published in Lasers in medical science (01-04-2022)“…The present study aimed at investigating the antidepressant and antioxidant actions of near-infrared (NIR) laser at a wavelength of 830 nm and power of 100 mW…”
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Neuroprotective effect of PPAR alpha and gamma agonists in a mouse model of amyloidogenesis through modulation of the Wnt/beta catenin pathway via targeting alpha- and beta-secretases
Published in Progress in neuro-psychopharmacology & biological psychiatry (08-03-2020)“…The present study was conducted to evaluate the efficacy of fenofibrate and pioglitazone in a mouse model of amyloidogenesis induced by amyloidβ (βA) peptide…”
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Antioxidant activity and hepatoprotective effects of whey protein and Spirulina in rats
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-05-2011)“…Abstract Objectives The aims of the present study were to evaluate the antioxidant, radical scavenging, and metal-chelating activity of whey protein…”
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Effect of caffeine-chitosan nanoparticles and α-lipoic acid on the cardiovascular changes induced in rat model of obesity
Published in International immunopharmacology (10-03-2024)“…[Display omitted] •Treatment with α-LA and/or Caf-CNs ameliorate the adverse effects of obesity on the myocardium.•The ability of α-LA and/or Caf-CNs to…”
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The effect of bisphenol A on some oxidative stress parameters and acetylcholinesterase activity in the heart of male albino rats
Published in Cytotechnology (Dordrecht) (01-01-2015)“…Bisphenol A (BPA) is an endocrine disrupting chemical used on a wide range in industry. Several studies reported that BPA may cause cardiovascular disorders in…”
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Therapeutic effects of alpha lipoic acid and/or caffeine-loaded chitosan nanoparticles on memory impairment and neurochemical changes in high-fat diet-induced obese rats
Published in Physiology & behavior (01-12-2024)“…•Obesity impaired memory and induced oxidative stress and neuroinflammation.•Obesity reduced cortical and hippocampal dopamine and hippocampal 5-HT.•Obesity…”
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Effect of alpha-lipoic acid and caffeine-loaded chitosan nanoparticles on obesity and its complications in liver and kidney in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-2023)“…The present work investigated the effect of α-lipoic acid (ALA) and caffeine-loaded chitosan nanoparticles (CAF-CS NPs) on obesity and its hepatic and renal…”
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Evaluation of the Therapeutic Effect of Curcumin-Conjugated Zinc Oxide Nanoparticles on Reserpine-Induced Depression in Wistar Rats
Published in Biological trace element research (01-06-2024)“…Depression, a devastating brain illness, necessitates the exploration of novel antidepressant treatments. We evaluated the antidepressant effects of free…”
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Evaluation of antioxidant and anti-inflammatory efficacy of caffeine in rat model of neurotoxicity
Published in Nutritional neuroscience (02-11-2019)“…Objective: The present study aims to investigate the neuroprotective effect of caffeine against aluminum chloride (AlCl 3 )-induced neurotoxicity in rats…”
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The Behavioral and Neurochemical Changes Induced by Boldenone and/or Tramadol in Adult Male Rats
Published in Neurochemical research (01-05-2023)“…Boldenone and tramadol are abused among large sectors of adolescents. Therefore, the behavioral changes concerned with memory and cognitive functions and…”
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Electrocortical and Biochemical Evaluation of Antidepressant Efficacy of Formulated Nanocurcumin
Published in Applied biochemistry and biotechnology (01-03-2019)“…The present study aims to evaluate the antidepressant efficacy of curcumin nanoparticles on rat model of depression induced by reserpine. Rats were divided…”
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Thymoquinone-encapsulated chitosan nanoparticles coated with polysorbate 80 as a novel treatment agent in a reserpine-induced depression animal model
Published in Physiology & behavior (01-08-2020)“…•The antidepressant effect of different formulations of free and loaded Thymoquinone was evaluated.•The prepared formulations were characterized for size,…”
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Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy
Published in Iranian journal of basic medical sciences (01-01-2021)“…The present study aims to investigate the pathological mechanisms mediating the effect of paradoxical sleep deprivation (PSD) for 48 hr on the spontaneous…”
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The Effect of Curcumin Nanoparticles on Cisplatin-Induced Cardiotoxicity in Male Wistar Albino Rats
Published in Cardiovascular toxicology (01-06-2021)“…The cardiotoxicity of chemotherapeutic drugs as cisplatin has become a major issue in recent years. The present study investigates the efficacy of curcumin…”
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Effect of curcumin nanoparticles on streptozotocin-induced male Wistar rat model of Alzheimer’s disease
Published in Metabolic brain disease (01-02-2022)“…Alzheimer’s disease (AD) is a progressive neurodegenerative disease that afflicts millions of people all over the world. Intracerebroventricular (ICV)…”
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