Search Results - "Khadka, Prabhat"

Silver Ions Caused Faster Diffusive Dynamics of Histone-Like Nucleoid-Structuring Proteins in Live Bacteria by Sadoon, Asmaa A, Khadka, Prabhat, Freeland, Jack, Gundampati, Ravi Kumar, Manso, Ryan H, Ruiz, Mason, Krishnamurthi, Venkata R, Thallapuranam, Suresh Kumar, Chen, Jingyi, Wang, Yong

“…The antimicrobial activity and mechanism of silver ions (Ag ) have gained broad attention in recent years. However, dynamic studies are rare in this field…”
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Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair by Lu, Huiming, Shamanna, Raghavendra A., de Freitas, Jessica K., Okur, Mustafa, Khadka, Prabhat, Kulikowicz, Tomasz, Holland, Priscella P., Tian, Jane, Croteau, Deborah L., Davis, Anthony J., Bohr, Vilhelm A.

“…Pathway choice within DNA double-strand break (DSB) repair is a tightly regulated process to maintain genome integrity. RECQL4, deficient in Rothmund-Thomson…”
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Nuclear import of hTERT requires a bipartite nuclear localization signal mediated by Akt phosphorylation by Chung, Jeeyun, Khadka, Prabhat, Chung, In Kwon

“…Sustained cell proliferation requires telomerase to maintain functional telomeres that are essential for chromosome integrity and protection. Although nuclear…”
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Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation by Chung, Jeeyun, Khadka, Prabhat, Chung, In Kwon

“…Sustained cell proliferation requires telomerase to maintain functional telomeres that are essential for chromosome integrity and protection. Although nuclear…”
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New Insights into the Antimicrobial Mechanism of Silver Ions Revealed by Super-Resolution Fluorescence Microscopy by Khadka, Prabhat, Rao Krishnamurthi, Venkata, Alqahtany, Meaad, Wang, Yong

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Nanoscale reorganizations of histone-like nucleoid structuring proteins in Escherichia coli are caused by silver nanoparticles by Alqahtany, Meaad, Khadka, Prabhat, Niyonshuti, Isabelle, Krishnamurthi, Venkata Rao, Sadoon, Asmaa A, Challapalli, Sai Divya, Chen, Jingyi, Wang, Yong

“…Silver nanoparticles (AgNPs) and ions (Ag ) have recently gained broad attention due to their antimicrobial effects against bacteria and other microbes. In…”
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CHIP Promotes Human Telomerase Reverse Transcriptase Degradation and Negatively Regulates Telomerase Activity by Lee, Ji Hoon, Khadka, Prabhat, Baek, Seung Han, Chung, In Kwon

“…The maintenance of eukaryotic telomeres requires telomerase, which is minimally composed of a telomerase reverse transcriptase (TERT) and an associated RNA…”
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Silver Ions Caused Faster Diffusion of H-NS Proteins in Live E. coli by Weakening the Binding Between H-NS Proteins and DNA by Sadoon, Asmaa A., Khadka, Prabhat, Freeland, Jack, Gundampati, Ravi, Mason, Rayan, Ruiz, Mazon, Thallapuranam, Suresh K., Chen, Jing, Wang, Yong

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Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles by Lee, Ji Hoon, Jeong, Sun Ah, Khadka, Prabhat, Hong, Juyeong, Chung, In Kwon

“…Telomerase, a unique ribonucleoprotein complex that contains the telomerase reverse transcriptase (TERT), the telomerase RNA component (TERC) and the…”
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Quantitative Investigations Reveal New Antimicrobial Mechanism of Silver Nanoparticles and Ions by Khadka, Prabhat, Haque, Mohammad, Rao Krishnamurthi, Venkata, Niyonshuti, Isabelle, Chen, Jingyi, Wang, Yong

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RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins by Khadka, Prabhat, Croteau, Deborah L., Bohr, Vilhelm A.

“…A model of RecQ helicases function to strand unwinding or strand annealing. A model of RecQ helicases function to strand unwinding or strand annealing. (a) (▪)…”
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Human RECQL1 participates in telomere maintenance by Popuri, Venkateswarlu, Hsu, Joseph, Khadka, Prabhat, Horvath, Kent, Liu, Yie, Croteau, Deborah L., Bohr, Vilhelm A.

“…A variety of human tumors employ alternative and recombination-mediated lengthening for telomere maintenance (ALT). Human RecQ helicases, such as BLM and WRN,…”
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Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase by Lee, Ji Hoon, Lee, Yang Sin, Jeong, Sun Ah, Khadka, Prabhat, Roth, Jürgen, Chung, In Kwon

“…The maintenance of human telomeres requires the ribonucleoprotein enzyme telomerase, which is composed of telomerase reverse transcriptase (TERT), telomerase…”
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Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation by Jeong, Sun Ah, Kim, Kuglae, Lee, Ji Hoon, Cha, Jeong Seok, Khadka, Prabhat, Cho, Hyun-Soo, Chung, In Kwon

“…Telomeres are essential for chromosome integrity and protection, and their maintenance requires the ribonucleoprotein enzyme telomerase. Previously, we have…”
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Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation by Jeong, Sun Ah, Kim, Kuglae, Lee, Ji Hoon, Cha, Jeong Seok, Khadka, Prabhat, Cho, Hyun-Soo, Chung, In Kwon

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Human RECQL1 participates in telomere maintenance by Popuri, Venkateswarlu, Hsu, Joseph, Khadka, Prabhat, Horvath, Kent, Liu, Yie, Croteau, Deborah L, Bohr, Vilhelm A

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Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities by Khadka, Prabhat, Hsu, Joseph K., Veith, Sebastian, Tadokoro, Takashi, Shamanna, Raghavendra A., Mangerich, Aswin, Croteau, Deborah L., Bohr, Vilhelm A.

“…Poly(ADP-ribose) (PAR) polymerase 1 (PARP1) catalyzes the poly(ADP-ribosyl)ation (PARylation) of proteins, a posttranslational modification which forms the…”
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DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres by Khadka, Prabhat, Lee, Ji Hoon, Baek, Seung Han, Oh, Sue Young, Chung, In Kwon

“…Human telomeres associate with shelterin, a six-protein complex that protects chromosome ends from being recognized as sites of DNA damage. The shelterin…”
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