Search Results - "Khadir, Abdelkrim"

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    Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management by Alkhatib, Ahmad, Tsang, Catherine, Tiss, Ali, Bahorun, Theeshan, Arefanian, Hossein, Barake, Roula, Khadir, Abdelkrim, Tuomilehto, Jaakko

    Published in Nutrients (01-12-2017)
    “…Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as…”
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    Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes by Khadir, Abdelkrim, Kavalakatt, Sina, Madhu, Dhanya, Devarajan, Sriraman, Abubaker, Jehad, Al-Mulla, Fahd, Tiss, Ali

    Published in Scientific reports (30-06-2020)
    “…Spexin is a novel neuropeptide playing an emerging role in metabolic diseases such as obesity and diabetes via involvement in energy homeostasis and food…”
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    Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes by Kavalakatt, Sina, Khadir, Abdelkrim, Madhu, Dhanya, Koistinen, Heikki A., Al-Mulla, Fahd, Tuomilehto, Jaakko, Abubaker, Jehad, Tiss, Ali

    Published in Scientific reports (02-08-2021)
    “…The neuropeptide urocortin 3 (UCN3) has a beneficial effect on metabolic disorders, such as obesity, diabetes, and cardiovascular disease. It has been reported…”
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    Fetuin-A levels are increased in the adipose tissue of diabetic obese humans but not in circulation by Khadir, Abdelkrim, Kavalakatt, Sina, Madhu, Dhanya, Hammad, Maha, Devarajan, Sriraman, Tuomilehto, Jaakko, Tiss, Ali

    Published in Lipids in health and disease (22-12-2018)
    “…The hepatokine fetuin-A is linked to obesity and type 2 diabetes, but its presence and expression in adipose tissue remain unclear. In this study, we aimed to…”
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    Fetuin-a expression profile in mouse and human adipose tissue by Khadir, Abdelkrim, Kavalakatt, Sina, Madhu, Dhanya, Tiss, Ali

    Published in Lipids in health and disease (12-03-2020)
    “…Fetuin-A (Fet-A) was one of the first hepatokines to be reportedly linked to metabolic diseases. Fet-A was also suggested to be an adipokine, but its…”
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    PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases by Khadir, Abdelkrim, Madhu, Dhanya, Kavalakatt, Sina, Cherian, Preethi, Alarouj, Monira, Bennakhi, Abdullah, Abubaker, Jehad, Tiss, Ali, Elkum, Naser

    Published in PloS one (14-01-2020)
    “…Cardiovascular disease (CVD) risks persist in patients despite treatment. CVD susceptibility also varies with sex and ethnicity and is not entirely explained…”
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    Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity by Khadir, Abdelkrim, Kavalakatt, Sina, Madhu, Dhanya, Cherian, Preethi, Al-Mulla, Fahd, Abubaker, Jehad, Tiss, Ali

    “…Epoxide hydrolase 2 (EPHX2) is an emerging therapeutic target in several immunometabolic disorders. EPHX2 metabolizes anti-inflammatory epoxyeicosatrienoic…”
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    Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity by Abu-Farha, Mohamed, Tiss, Ali, Abubaker, Jehad, Khadir, Abdelkrim, Al-Ghimlas, Fahad, Al-Khairi, Irina, Baturcam, Engin, Cherian, Preethi, Elkum, Naser, Hammad, Maha, John, Jeena, Kavalakatt, Sina, Warsame, Samia, Behbehani, Kazem, Dermime, Said, Dehbi, Mohammed

    Published in PloS one (24-09-2013)
    “…Sedentary lifestyle and excessive energy intake are prominent contributors to obesity; a major risk factors for the development of insulin resistance, type 2…”
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    Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese by Khadir, Abdelkrim, Kavalakatt, Sina, Cherian, Preethi, Warsame, Samia, Abubaker, Jehad Ahmed, Dehbi, Mohammed, Tiss, Ali

    Published in Frontiers in endocrinology (Lausanne) (06-02-2018)
    “…Heat shock protein 60 (HSP60) is a key protein in the crosstalk between cellular stress and inflammation. However, the status of HSP60 in diabetes and obesity…”
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    Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise by Kavalakatt, Sina, Khadir, Abdelkrim, Madhu, Dhanya, Hammad, Maha, Devarajan, Sriraman, Abubaker, Jehad, Al-Mulla, Fahd, Tuomilehto, Jaakko, Tiss, Ali

    Published in Frontiers in endocrinology (Lausanne) (06-11-2019)
    “…Urocortin3 (UCN3) regulates metabolic functions and is involved in cellular stress response. Although UCN3 is expressed in human adipose tissue, the…”
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    DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise by Abubaker, Jehad, Tiss, Ali, Abu-Farha, Mohamed, Al-Ghimlas, Fahad, Al-Khairi, Irina, Baturcam, Engin, Cherian, Preethi, Elkum, Naser, Hammad, Maha, John, Jeena, Kavalakatt, Sina, Khadir, Abdelkrim, Warsame, Samia, Dermime, Said, Behbehani, Kazem, Dehbi, Mohammed

    Published in PloS one (24-07-2013)
    “…Obesity is a major risk factor for a myriad of disorders such as insulin resistance and diabetes. The mechanisms underlying these chronic conditions are…”
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    Urocortin Neuropeptide Levels Are Impaired in the PBMCs of Overweight Children by Kavalakatt, Sina, Khadir, Abdelkrim, Kochumon, Shihab, Madhu, Dhanya, Devarajan, Sriraman, Hammad, Maha, Alam-Eldin, Nada, Warsame, Samia, Al-Kandari, Hessa, AlMahdi, Maria, Ahmad, Rasheed, Koistinen, Heikki A, Tuomilehto, Jaakko, Al-Mulla, Fahd, Abubaker, Jehad, Tiss, Ali

    Published in Nutrients (18-01-2022)
    “…The corticotropin-releasing hormone (CRH) and urocortins (UCNs) have been implicated in energy homeostasis and the cellular stress response. However, the…”
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    Gender-Specific Association of Oxidative Stress and Inflammation with Cardiovascular Risk Factors in Arab Population by Dehbi, Mohammed, Behbehani, Kazem, Kavalakatt, Sina, Tiss, Ali, Khadir, Abdelkrim, Elkum, Naser

    Published in Mediators of Inflammation (01-01-2015)
    “…Background. The impact of gender difference on the association between metabolic stress and cardiovascular disease (CVD) remains unclear. We have investigated,…”
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    Complement C5b-9 Membrane Attack Complex Increases Expression of Endoplasmic Reticulum Stress Proteins in Glomerular Epithelial Cells by Cybulsky, Andrey V, Takano, Tomoko, Papillon, Joan, Khadir, Abdelkrim, Liu, Jianhong, Peng, Hongwei

    Published in The Journal of biological chemistry (01-11-2002)
    “…In the passive Heymann nephritis (PHN) model of membranous nephropathy, complement C5b-9 induces glomerular epithelial cell (GEC) injury, proteinuria, and…”
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    Complement Activates the c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase in Glomerular Epithelial Cells by Peng, Hongwei, Takano, Tomoko, Papillon, Joan, Bijian, Krikor, Khadir, Abdelkrim, Cybulsky, Andrey V

    Published in The Journal of immunology (1950) (01-09-2002)
    “…In the rat passive Heymann nephritis model of membranous nephropathy, complement C5b-9 induces sublethal glomerular epithelial cell (GEC) injury and…”
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    The actin cytoskeleton facilitates complement-mediated activation of cytosolic phospholipase A2 by Cybulsky, Andrey V, Takano, Tomoko, Papillon, Joan, Khadir, Abdelkrim, Bijian, Krikor, Le Berre, Ludmilla

    “…Cytosolic PLA(2)-alpha (cPLA(2)) and metabolites of arachidonic acid (AA) are key mediators of complement-dependent glomerular epithelial cell (GEC) injury…”
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