Search Results - "Khadir, Abdelkrim"
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Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management
Published in Nutrients (01-12-2017)“…Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as…”
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Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes
Published in Scientific reports (30-06-2020)“…Spexin is a novel neuropeptide playing an emerging role in metabolic diseases such as obesity and diabetes via involvement in energy homeostasis and food…”
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Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes
Published in Scientific reports (02-08-2021)“…The neuropeptide urocortin 3 (UCN3) has a beneficial effect on metabolic disorders, such as obesity, diabetes, and cardiovascular disease. It has been reported…”
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Fetuin-A levels are increased in the adipose tissue of diabetic obese humans but not in circulation
Published in Lipids in health and disease (22-12-2018)“…The hepatokine fetuin-A is linked to obesity and type 2 diabetes, but its presence and expression in adipose tissue remain unclear. In this study, we aimed to…”
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Fetuin-a expression profile in mouse and human adipose tissue
Published in Lipids in health and disease (12-03-2020)“…Fetuin-A (Fet-A) was one of the first hepatokines to be reportedly linked to metabolic diseases. Fet-A was also suggested to be an adipokine, but its…”
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PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases
Published in PloS one (14-01-2020)“…Cardiovascular disease (CVD) risks persist in patients despite treatment. CVD susceptibility also varies with sex and ethnicity and is not entirely explained…”
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Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity
Published in International journal of molecular sciences (17-03-2020)“…Epoxide hydrolase 2 (EPHX2) is an emerging therapeutic target in several immunometabolic disorders. EPHX2 metabolizes anti-inflammatory epoxyeicosatrienoic…”
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Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity
Published in PloS one (24-09-2013)“…Sedentary lifestyle and excessive energy intake are prominent contributors to obesity; a major risk factors for the development of insulin resistance, type 2…”
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
Published in Frontiers in endocrinology (Lausanne) (06-02-2018)“…Heat shock protein 60 (HSP60) is a key protein in the crosstalk between cellular stress and inflammation. However, the status of HSP60 in diabetes and obesity…”
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10
The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors
Published in Molecular and Cellular Biology (01-11-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise
Published in Frontiers in endocrinology (Lausanne) (06-11-2019)“…Urocortin3 (UCN3) regulates metabolic functions and is involved in cellular stress response. Although UCN3 is expressed in human adipose tissue, the…”
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MAP kinase phosphatase DUSP1 is overexpressed in obese humans and modulated by physical exercise
Published in American journal of physiology: endocrinology and metabolism (01-01-2015)“…Chronic low-grade inflammation and dysregulation of the stress defense system are cardinal features of obesity, a major risk factor for the development of…”
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DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise
Published in PloS one (24-07-2013)“…Obesity is a major risk factor for a myriad of disorders such as insulin resistance and diabetes. The mechanisms underlying these chronic conditions are…”
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Urocortin Neuropeptide Levels Are Impaired in the PBMCs of Overweight Children
Published in Nutrients (18-01-2022)“…The corticotropin-releasing hormone (CRH) and urocortins (UCNs) have been implicated in energy homeostasis and the cellular stress response. However, the…”
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15
Gender-Specific Association of Oxidative Stress and Inflammation with Cardiovascular Risk Factors in Arab Population
Published in Mediators of Inflammation (01-01-2015)“…Background. The impact of gender difference on the association between metabolic stress and cardiovascular disease (CVD) remains unclear. We have investigated,…”
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Physical Exercise Reduces the Expression of RANTES and Its CCR5 Receptor in the Adipose Tissue of Obese Humans
Published in Mediators of Inflammation (01-01-2014)“…RANTES and its CCR5 receptor trigger inflammation and its progression to insulin resistance in obese. In the present study, we investigated for the first time…”
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Complement C5b-9 Membrane Attack Complex Increases Expression of Endoplasmic Reticulum Stress Proteins in Glomerular Epithelial Cells
Published in The Journal of biological chemistry (01-11-2002)“…In the passive Heymann nephritis (PHN) model of membranous nephropathy, complement C5b-9 induces glomerular epithelial cell (GEC) injury, proteinuria, and…”
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Complement Activates the c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase in Glomerular Epithelial Cells
Published in The Journal of immunology (1950) (01-09-2002)“…In the rat passive Heymann nephritis model of membranous nephropathy, complement C5b-9 induces sublethal glomerular epithelial cell (GEC) injury and…”
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The actin cytoskeleton facilitates complement-mediated activation of cytosolic phospholipase A2
Published in American journal of physiology. Renal physiology (01-03-2004)“…Cytosolic PLA(2)-alpha (cPLA(2)) and metabolites of arachidonic acid (AA) are key mediators of complement-dependent glomerular epithelial cell (GEC) injury…”
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Association of obesity with down-regulation of heat shock protein 40 expression and evidence that exercise retrieves its normal expression
Published in BMC proceedings (01-06-2012)“…Doc number: P1…”
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